Publications by authors named "Tingfei Gu"
Anastomotic leakage (AL) is a major complication of colorectal surgery that can lead to abdominal infection and systemic inflammatory response. Meanwhile, the microbiota and immune microenvironment at the anastomosis are closely related to the formation of AL. Presently, a considerable volume of research is directed towards investigating the colorectal microenvironment in AL.
View Article and Find Full Text PDFObjectives: This study aimed to assess the surgical quality, safety, and healthcare utilization associated with gastric cancer surgery in China, using international studies for benchmarking.
Design: A prospective registered study was conducted utilizing data from the Prevalence of Abdominal Complications After Gastroenterological Surgery study, comprised of 1859 patients without postoperative complications (non-POC group) and 412 patients with at least one POC group. Baseline characteristics, surgical outcomes, and healthcare utilization were compared between groups, and results were further contextualized through a review of international multicenter studies.
Article Synopsis
- * A study involving 330 patients showed that proximal gastrectomy (PG) and total gastrectomy (TG) had similar short-term and long-term survival rates, with no significant differences noted in postop recovery.
- * PG might provide better overall survival for tumors under 4 cm in diameter, while TG is preferred for larger tumors; further studies are needed to confirm these results for clinical use.
Genomic characterization of peritoneal lavage cytology-positive gastric cancer.
Chin J Cancer Res
February 2024
Article Synopsis
- Positive peritoneal lavage cytology (CY1) in gastric cancer signifies a poor prognosis due to the high likelihood of peritoneal metastasis, but its underlying mechanisms and treatment options are still unclear.
- A study analyzed genetic data from 17 CY1 and 31 matched CY0 gastric cancer patients to identify important driver and marker genes associated with these conditions through whole exome sequencing.
- The results indicated no significant genetic differences between CY1 and CY0, suggesting that CY1 may be more of a progression stage of CY0 rather than a distinct subtype, which could influence future treatment strategies and clinical trials.
Background: Pregnancy anemia is a global health concern. However, to our knowledge, there still has little consensus on the reference value of hemoglobin levels. Particularly, little evidence from China was accessible in most existing guidelines.
View Article and Find Full Text PDFAn Evaluation of Exposure to 18 Toxic and/or Essential Trace Elements Exposure in Maternal and Cord Plasma during Pregnancy at Advanced Maternal Age.
Int J Environ Res Public Health
November 2022
Pregnant women of advanced maternal age (AMA) are vulnerable to exposure to the surrounding environment. Assessment of trace elements in pregnant women living in specific areas is important for biomonitoring. However, exposure levels and variation patterns during pregnancy remains controversial and attracts extensive public concern.
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