Publications by authors named "Tian-Shu He"
The atomic-level dispersion of noble metals in porous materials is prospective for highly efficient catalyst systems but is still inscrutable. Inspired by sandwich compounds, platinum (Pt) atoms were rationally confined within a metal-organic framework (MOF) through pore space partition by conjugate interactions between Pt and parallel-distributed aromatic pore partitioners, forming 1D infinite Pt arrays. By regulating the distance between adjacent aromatic rings from 7 to 4.
View Article and Find Full Text PDFSystematic analysis of the adverse effects of commonly used clinical tetracycline drugs based on the FAERS database.
Expert Opin Drug Saf
August 2025
Article Synopsis
- Tetracyclines are widely used antibacterial drugs, but their adverse effects (AEs) had not been systematically analyzed until this study, which utilized the FDA's FAERS database from 2004 to 2023.
- The research identified 15,020 cases and calculated signal values for various AEs linked to different tetracycline drugs, with notable findings such as doxycycline causing gastrointestinal issues and minocycline linked to skin pigmentation changes.
- The study highlighted previously unreported AEs like ototoxicity, along with psychiatric effects from doxycycline and concerns related to tumors from minocycline, suggesting that awareness of these risks should be increased among healthcare providers and patients.