Exploring the Chemopreventive and Antioxidant Effects of Spearmint Leaf Hydroethanolic Extract in HPV16-transgenic Mice.

Background/aim: Human papillomavirus (HPV) is the most common sexually transmitted infectious agent and, in cases of persistent infection, may cause cancer. This study evaluated the toxicological and antitumor properties of extract (MSE) in KP14HPV16 mice, which carry HPV16 oncogenes.

Materials And Methods: Thirty-three female FVB/n mice (), including 17 HPV-transgenic and 16 wild-type (WT) mice, were divided into six groups.