Conventional drug delivery systems for cancer therapy have faced various challenges, including side effects and inadequate drug release behavior, which require addressing. Recently, targeted nanocarriers have attracted considerable attention to overcome these challenges. Stimuli-responsive chitosan combined with lipid-based carriers (CLBCs) provides an innovative targeted system that can release its encapsulated drug in response to stimuli, such as pH and temperature, in the tumor site.
View Article and Find Full Text PDFThe biopolymer chitosan, which is derived from chitin, has shown great promise for tissue regeneration and regulated drug delivery. Its broad-spectrum antibacterial action, low toxicity, biocompatibility, and many other attributes make it appealing for use in biomedical applications. Crucially, chitosan may be synthesized into a range of forms that can be customized to provide desired results, such as hydrogels, membranes, scaffolds, and nanoparticles.
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