Heliyon
February 2025
[This corrects the article DOI: 10.1016/j.heliyon.
View Article and Find Full Text PDFBackground: Some women experience menstrual disorders such as polymenorrhea, oligomenorrhea, and menorrhagia, which are not only influenced by biological factors but also by lifestyle and psychosocial factors. Understanding menstrual disorders is essential for women's health and quality of life.
Objectives: To identify policies that are needed to prevent menstrual disorders, we investigated the prevalence and risk factors of menstrual disorders in this study.
Objectives: Humidifier disinfectants (HDs) were sold in Korea from 1994 until their recall in 2011. We examined the incidence patterns of 8 respiratory diseases before and after the HD recall and estimated the attributable risk in the Korean population.
Methods: Using National Health Insurance data from 2002 to 2019, we performed age-cohort-period and differences-in-diffference analyses (comparing periods before vs.
In South Korea, a Human Biomonitoring (HBM) program, known as the Korean National Environmental Health Survey (KoNEHS), was launched in 2009. This study aims to provide an overview of environmental chemical exposures in South Korea based on data from the KoNEHS cycle 4 (2018-2020). To ensure population representativeness, Koreans aged 3 years and older were recruited from 426 sites across the country.
View Article and Find Full Text PDFEnviron Epidemiol
October 2024
Background: Evidence linking environmental toxicants to sleep quality is growing; however, these associations during pregnancy remain unclear. We examined the associations of repeated measures of urinary phthalates in early and late pregnancy with multiple markers of sleep quality among pregnant women.
Methods: The study population included 2324 pregnant women from the Korean Children's Environmental Health Study.
Polyhexamethylene guanidine phosphate (PHMG-p) is a major component in humidifier disinfectants, which cause life-threatening lung injuries. However, to our knowledge, no published studies have investigated associations between PHMG-p dose and lung damage severity with long-term follow-up. Therefore, we evaluated longitudinal dose-dependent changes in lung injuries using repeated chest computed tomography (CT).
View Article and Find Full Text PDFBackground: Particulate air pollution and residential greenness are associated with sleep quality in the general population; however, their influence on maternal sleep quality during pregnancy has not been assessed.
Objective: This cross-sectional study investigated the individual and interactive effects of exposure to particulate matter (PM) air pollution and residential greenness on sleep quality in pregnant women.
Methods: Pregnant women (n = 4933) enrolled in the Korean Children's Environmental Health Study with sleep quality information and residential address were included.
Background: Exposure to perfluoroalkyl substances (PFAS) may increase the risk of liver disease by disrupting cholesterol and lipid synthesis/metabolism, leading to higher liver-enzyme concentrations. However, most studies assessing association between PFAS and liver enzymes focused on individual PFAS. Moreover, PFAS concentrations differ based on sex and obesity status, and it remains unclear whether these factors affect associations with liver function.
View Article and Find Full Text PDFEmerging evidence suggest that long-term exposure to air pollution may induce adverse effects on the central nervous system. However, no study explored the associations in large industrial complex (IC) areas which are one of the major contributors to air pollution. Therefore, we aimed to investigate the pollution status and the association between residential proximity and incidence of neurological diseases near two major ICs characterized as multi-purposed ICs in Korea.
View Article and Find Full Text PDFParabens are used as a preservative in several consumer products including cosmetics, personal care products, and medicinal products. These chemicals have been suspected for estrogenicity and potential adverse endocrine outcomes in humans. For the first time, exposure profiles and potential sources of major parabens are investigated for a nationally representative population of children and adolescents of Korea.
View Article and Find Full Text PDFThe Asbestos Injury Relief Act in Korea requires that asbestos exposure be assessed through clinical examination and chest computed tomography (CT). However, a more specific measurement of asbestos characteristics in the lung tissue may be appropriate. We aimed to investigate the asbestos burden and characterize asbestos fibers in patients with lung cancer and ultimately assess the relationship between occupational and environmental asbestos exposure and lung cancer in Korea.
View Article and Find Full Text PDFEnviron Anal Health Toxicol
June 2020
A mixture of 5-chloro-2-methylisothiazol-3(2H)-one/2-methylisothiazol-3(2H)-one (CMIT/MIT) had been used as an active ingredient in humidifier disinfectants (HDs). Owing to its high reactivity, the atmospheric concentration of CMIT/MIT, following its use in HD, would be lower than expected assuming that it is removed by ventilation only. In order to evaluate the exposure concentration of CMIT/MIT used as an HD, room-scale chamber studies were conducted under plausible use of three different HD doses at air change rates (ACR) of 0.
View Article and Find Full Text PDFEnviron Int
April 2020
Background: The Mothers and Children's Environmental Health study (MOCEH) is a multi-centric prospective birth cohort study investigating effects of various environmental pollutants like heavy metals, endocrine disruptors, air pollutants, nutrition and lifestyle on birth outcomes, growth and development, health and disease of children. In this study, we report all the outcomes from the MOCEH study describing the different environmental pollutants affecting children's health and disease.
Methods: In MOCEH study, 1,751 pregnant women in their first trimester were recruited at 3 centers from 2006 to 2010 in South Korea.
Sci Total Environ
July 2019
Background: Neighborhood greenness appears to be beneficial to human health. However, there are few studies on the relationship between greenness of children's residential communities and their neurobehavioral health.
Objective: In this cross-sectional study, we examined the association between neighborhood greenness of children's residential area and their neurobehavioral health.
The Korean CHildren's ENvironmental health Study (Ko-CHENS) is a nationwide prospective birth cohort showing the correlation between the environmental exposures and the health effects to prevent the environmental diseases in children, and it provides the guidelines for the environmental hazardous factors, applying the life-course approach to the environmental-health management system. The Ko-CHENS consists of 5000 Core and 65,000 Main Cohorts. The children in the Core Cohort are followed up at 6 months, every year before their admission into the elementary school, and every 3 years from the first year after this admission.
View Article and Find Full Text PDFSci Total Environ
December 2018
Perfluoroalkyl acids (PFAAs) have been widely used in human environment, and their exposure among general population has been frequently reported. However, extent of PFAAs exposure and their potential effects among children are not well characterized. In this study, children of between 3 and 18 years of age (n = 150) were recruited in Seoul and Gyeonggi, Korea, and the serum levels of 16 PFAAs along with lipids and thyroid hormones were measured.
View Article and Find Full Text PDFInt J Environ Res Public Health
September 2017
Exposure to harmful environmental factors is particularly detrimental to younger children. We investigated the relationship between environmental tobacco smoke (ETS) exposure in pre-schoolers at home and the level of high-sensitivity C-reactive protein (hs-CRP), a predictive factor for cardiovascular disease. This study was conducted in 2014 and was based on the data of preschool children from the Korean Environmental Health Survey in Children and Adolescents (2012 to 2014), a nationally representative sample.
View Article and Find Full Text PDFSci Total Environ
December 2017
The present study assessed the associations of heavy metal concentrations in pregnant women with the concentrations in their children during early childhood. This study is a part of the Mothers' and Children's Environmental Health (MOCEH) study, a Korean multi-center prospective birth cohort study of 1751 pregnant women who were recruited from 2006 to 2010. We completed the follow-up of children who were 5years-old in 2016.
View Article and Find Full Text PDFBest Pract Res Clin Obstet Gynaecol
November 2017
Fibroid uterus can be managed medically, surgically, or through non-extirpative procedures, depending on the clinical situation. Myomectomy may be beneficial, especially to those desiring to preserve the uterus and/or fertility, with outcomes comparable to those of hysterectomy, with a laparoscopic approach being favored when feasible. For definitive therapy, hysterectomy can be pursued where the surgical approach should be individualized.
View Article and Find Full Text PDFBackground: Studies examining prenatal exposure to mobile phone use and its effect on child neurodevelopment show different results, according to child's developmental stages.
Objectives: To examine neurodevelopment in children up to 36 months of age, following prenatal mobile phone use and radiofrequency radiation (RFR) exposure, in relation to prenatal lead exposure.
Methods: We analyzed 1198 mother-child pairs from a prospective cohort study (the Mothers and Children's Environmental Health Study).
Background: Phthalates and bisphenol A (BPA) have been used extensively in many consumer products, resulting in widespread exposure in the general population. Studies have suggested associations between exposure to phthalates and BPA, and serum thyroid hormone levels, but confirmation on larger human populations is warranted.
Methods: Data obtained from nationally representative Korean adults (n=6003) recruited for the second round of the Korean National Environmental Health Survey (KoNEHS), 2012-2014, were employed.
Robotic-assisted surgery has seen a rapid development and integration in the field of gynecology. Since the approval of the use of robot for gynecological surgery and considering its several advantages over conventional laparoscopy, it has been widely incorporated especially in the field of reproductive surgery. Uterine fibroids are the most common benign tumors of the female reproductive tract.
View Article and Find Full Text PDFSemin Reprod Med
January 2017
Surgical approaches to endometriosis patients with chronic pelvic pain are multimodal and require individualization. Laparoscopic approaches are preferred over laparotomy when conservatively treating endometriosis via excision or ablation/fulguration of lesions. The available data support cystectomy over fenestration or fulguration for endometriomas; however, there may be associated decreases in ovarian reserve with endometrioma treatment.
View Article and Find Full Text PDFInt J Hyg Environ Health
March 2017
National biomonitoring program can offer solid scientific evidence on exposure profiles of environmental chemicals at a national level, and provide a snapshot of changing exposure level over time. Therefore, several countries have maintained such programs for developing environmental health policies. The Korean National Environmental Health Survey (KoNEHS) was designed to understand the level of human exposure to environmental chemicals by time and location, and to identify possible sources of such exposure.
View Article and Find Full Text PDFInt J Environ Res Public Health
September 2016
From a public health perspective, there is growing concern about dietary mercury intake as the most important source of mercury exposure. This study was performed to estimate dietary mercury exposure and to analyze the association between mercury intake and blood mercury levels in Koreans. The study subjects were 553 adults, comprising a 10% representative subsample of the Korean National Environmental Health Survey (KoNEHS) 2012-2014, who completed a health examination, a face-to-face interview, and a three-day food record.
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