Publications by authors named "Hyojee Joung"

Background: Soy and isoflavones have been linked to various health benefits, but their associations with all-cause and cause-specific mortality remain unclear.

Objectives: We examined the associations of dietary intakes of isoflavones, soy protein, and soy foods with mortality risk in a population-based cohort study.

Methods: We included 39,286 adults aged ≥ 19 y from the Korea National Health and Nutrition Examination Survey (2007-2015).

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Background: The association between dietary soy and isoflavone intake and mortality remains inconclusive. This study aimed to examine the relationships of dietary intakes of isoflavones, soy protein, and soy foods with all-cause, cancer, and cardiovascular disease (CVD) mortality in Korean adults.

Methods: This prospective cohort study included 118,450 Korean adults aged 40-79 years from the Health Examinees Study (2004-2013).

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The role of isoflavones in breast cancer, particularly their relationship with inflammatory markers, remains underexplored. We hypothesized that higher intakes of soy and isoflavones are inversely associated with inflammatory markers in breast cancer survivors. This cross-sectional study included 432 breast cancer survivors (mean age: 52 years).

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Background/objectives: Isoflavones are estrogen-like compounds found in plants and their health effects remain equivocal. We investigated dietary isoflavone intake and its associated factors in Korean breast cancer survivors, with a comparison to cancer-free women.

Subjects/methods: The usual dietary intake of breast cancer survivors (n = 981, mean age 52 yrs) in 9 hospitals between 2012 and 2019 was assessed using 3-day food records or food frequency questionnaires (FFQs).

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Background/objectives: Despite the increasing intake of animal-based protein and the growing number of single-person households (SPHs) in Korean populations, no studies have analyzed the relationship of protein intake by source with metabolic syndrome (MetS) according to household type. This study examined the association between protein intake (plant- and animal-based sources) and MetS risk factors in SPH and multi-person households (MPHs) among Korean adults.

Method: A total of 12,022 participants aged 30-64 years (SPH: 982; MPH: 11,040) were selected from the 2016-2021 Korea National Health and Nutrition Examination Survey.

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Background/objectives: Perceived diet quality (PDQ) has been suggested as an easy-to-use dietary assessment tool. However, its practicality and efficiency are still questionable. This study aimed to gauge the utility of PDQ as an alternative dietary assessment tool among Korean adults by examining PDQ and its associated factors.

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Context: Increasing global kimchi consumption has prompted interest in its health impact. However, comprehensive reviews of the influence of kimchi on cardiometabolic risk factors, especially meta-analyses, remain limited.

Objective: This review assessed the impact of fermented kimchi consumption on cardiometabolic risk factors by systematically reviewing human intervention and prospective cohort studies, and conducting a meta-analysis of intervention studies.

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Background/objectives: We investigated the effects of ultraprocessed food (UPF) consumption on metabolic disorders (e.g., adiposity, metabolic associated steatotic liver disease [MASLD], and insulin resistance) in children and adolescents with obesity to improve dietary guidelines and public health strategies.

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Article Synopsis
  • Mitochondrial dysfunction is linked to obesity and diabetes, with environmental pollutants possibly increasing diabetes risk through dioxin-like substances that affect mitochondrial health and lung function.
  • A study of 1371 adults from the Korean Genome Epidemiologic Study found that dioxin-like mitochondria inhibitor substances (MIS) were associated with body mass index (BMI) and lung function, indicating a complex relationship between these factors.
  • Results suggested that higher levels of MIS negatively impacted mitochondrial function, which subsequently affected both BMI and lung health, emphasizing the need for better understanding of mitochondrial health in the context of metabolic disorders and aging.
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Objectives: Although the prevalence of metabolic syndrome has increased among Koreans, the specific health benefits of the Korean Healthy Diet score remain unexplored. This study aimed to evaluate the association between the Korean Healthy Diet score and metabolic syndrome and to identify the optimal cutoff of the Korean Healthy Diet score for reducing metabolic syndrome prevalence.

Methods: This cross-sectional study used data from 11,403 participants of the seventh and eighth Korea National Health and Nutrition Examination Survey.

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Article Synopsis
  • The study investigated the link between dietary intake and exposure to endocrine-disrupting chemicals (EDCs) among middle-aged Koreans, focusing on surrogate biomarkers like aryl hydrocarbon receptor ligands (AhRL) and mitochondrial function indicators (MIS-ATP and MIS-ROS).
  • Results indicated that fish consumption was positively correlated with higher AhRL levels, suggesting increased EDC exposure, while cruciferous vegetables showed a negative association with AhRL levels and a positive correlation with MIS-ATP levels.
  • Overall, higher fish intake appears to increase the risk of EDC-related bioactivity, contrasting with some protective effects of consuming cruciferous vegetables against high AhRL levels.
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Dietary biomarkers in urine remain elusive when evaluating diet-induced oxidative stress and inflammation. In our previous study, we conducted a randomized controlled crossover trial to compare the short-term (4-weeks) effects of the balanced Korean diet (BKD) with Western diets, including the 2010 dietary guidelines for Americans (2010 DGA) and typical American diet (TAD), on various metabolic indices in obese Korean adults. Building on this work, the current research focuses on the impact of these dietary interventions on oxidative stress (d-ROMs and BAP) and inflammation (CRP, TNF-α, IL-6, IL-1β, MCP-1) biomarkers in serum, and the concurrent urine metabolomes.

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Background: According to previous studies, stress and job burnout among medical personnel increased during the COVID-19 pandemic. This study analyzed the effect of the experience of COVID-19 response work on the intention of municipal hospital staffs to leave their workplaces during the pandemic.

Methods: The 3556 employees who had worked for more than 1 year at one of the eight Seoul Municipal Hospitals that either provided inpatient treatment for quarantined COVID-19 patients or operated as screening clinics were taken as the study population.

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Purpose: Our study was performed to observe children with obesity by using accelerometers and identify their differences in blood lipid levels, insulin resistance, and adipokines based on their physical activity levels.

Methods: 197 obese children were classified into three groups based on their physical activity levels over a period of 7 days, using the average counts per minute: Sedentary Time (ST), Light Physical Activity (LPA), and Moderate to Vigorous Intensity Physical Activity (MVPA). Blood lipids, including triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C), were analyzed.

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Article Synopsis
  • The study aimed to assess how skin carotenoid status (SCS) changes in response to different carotenoid intake levels through whole-diet interventions, focusing on its potential as a dietary biomarker.
  • Eighty participants aged 20 to 49 were divided into two groups: one on a high-carotenoid diet and the other on a control diet for six weeks, with SCS and blood carotenoid levels measured during and after the intervention.
  • Results showed that the high-carotenoid group experienced a significantly greater increase in SCS compared to the control group, indicating that SCS could effectively monitor carotenoid intake from fruits and vegetables.
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The increasing prevalence of obesity is a serious concern in Korea. However, there is currently no available food-frequency questionnaire (FFQ) for examining the dietary patterns of adults with obesity. This study aimed to develop a semi-quantitative FFQ tailored to Korean adults with obesity.

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We aimed to examine the association between dietary isoflavone intake and the risk of breast cancer recurrence and summarize evidence on the role of dietary isoflavone intake in breast cancer prognosis. This prospective study included 592 breast cancer survivors who completed a dietary assessment. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox proportional hazards models.

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Resonance Raman spectroscopy (RRS) has been used as a reference method for measuring skin carotenoid levels (SCL), which indicate vegetable and fruit intake. However, RRS is not an easy-to-use method in SCL measurement due to its complicated implementation. In this study, a commercial spectrophotometer based on reflection spectroscopy (RS), which is relatively simple and inexpensive, was evaluated to confirm usability compared with RRS in measuring SCL.

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Background: Dyslipidemia is a major risk factor for cardiovascular diseases and appropriate intake of amino acids may be helpful for the management of dyslipidemia. However, evidence of an association between amino acid intake and dyslipidemia in Korean adults is limited.

Objective: The purpose of this study was to investigate how the incidence of dyslipidemia in Korean adults is associated with the consumption of amino acids, essential and nonessential types, as well as the sources of these amino acids from food.

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Despite consistent evidence that greater consumption of fruits and vegetables (FV) is associated with significant reductions in chronic disease morbidity and mortality, the majority of adults in the United States consume less than the amounts recommended by public health agencies. As such, there is a critical need to design and implement effective programs and policies to facilitate increases in FV consumption for the prevention of these diseases. To accomplish this, an accurate, inexpensive, and convenient method for estimating the dietary FV intake is required.

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Scope: Animal protein intake among Koreans has recently increased. However, there is limited evidence on the association of meat and fish/seafood intake and mortality.

Methods And Results: This study uses three representative prospective cohorts in Korea and 134,586 eligible participants are selected.

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Blood carotenoid concentration measurement is considered the gold standard for fruit and vegetable (F&V) intake estimation; however, this method is invasive and expensive. Recently, skin carotenoid status (SCS) measured by optical sensors has been evaluated as a promising parameter for F&V intake estimation. In this cross-sectional study, we aimed to validate the utility of resonance Raman spectroscopy (RRS)-assessed SCS as a biomarker of F&V intake in Korean adults.

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Background And Aims: Cardiovascular disease (CVD) and hypertension are the main causes of global death. We aimed to investigate the independent and combined effects of smoking and alcohol consumption on CVD risk among Koreans with elevated blood pressure (BP).

Methods And Results: Adults aged 20-65 years with elevated BP and without pre-existing CVDs were selected from the National Health Insurance Service-National Sample Cohort version 2.

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Objectives: Antioxidants are common dietary compounds with multiple health benefits. This study aimed to identify the association between dietary antioxidant consumption and the incidence of type 2 diabetes (T2D) mellitus (defined using the Korean Diabetes Association criteria) in South Korean adults.

Design: Baseline and follow-up data from the Health Examinees (HEXA) study, a large-scale community-based genomic cohort study conducted in South Korea SETTING: A South Korean community.

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The associations of lifestyle and environment with metabolic syndrome (MetS) and cardiovascular disease have recently resulted in increased attention in research. This study aimed to examine interactive associations among carbohydrate and fat intake, physical environment (i.e.

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