Anatomical-Based Diagnosis and Filler Injection Techniques: Nasolabial Folds.

Nasolabial folds significantly impact facial appearance and are a common aesthetic concern. This article reviews anatomic considerations and filler injection techniques for treating these folds, with a focus on the Korean population. The dermal filler used in this study is Maili hyaluronic acid filler (Sinclair Pharma), derived from a novel proprietary manufacturing technology known as OxiFree™ technology (Kylane Laboratoires , Switzerland).

Hyaluronic acid filler injection for upper body aesthetic contouring.

The demand for non-surgical upper body enhancement continues to grow, particularly among men seeking improved muscular definition without the risks of surgery or functional compromise. This case report presents a novel protocol using high G-prime hyaluronic acid (HA) fillers (Sedifill; Maypharm, Seoul, Republic of Korea) to contour the pectoralis major, deltoid, biceps, and brachioradialis in a 41-year-old male with moderate subcutaneous adiposity (BMI: 25 kg/m²; body fat: 21 %). A total of 134 mL of filler was injected subcutaneously using a layered technique with dynamic assessment and feathering to enhance muscle visibility while integrating with surrounding fat.

Anatomical-Based Diagnosis and Filler Injection Techniques: Perioral Wrinkles.

This study focuses on anatomically based diagnosis and filler injection techniques for managing perioral wrinkles, which present unique challenges due to complex vascular anatomy and diverse wrinkle types. Key perioral wrinkles include vertical lip wrinkles (smoker's lines), oblique lip-chin creases, labiomental creases, central chin creases, and marionette lines. Effective treatment requires understanding the underlying anatomy and careful procedural planning.

Combination Therapy With Poly D-L Lactic Acid and Autologous Fat Transplantation for Infraorbital Rejuvenation.

Background: Multiple approaches exist for treating infraorbital hollowing, including hyaluronic acid fillers and autologous fat transfer. However, traditional single-modality treatments often present limitations such as the Tyndall effect or unpredictable fat retention rates.

Objective: To evaluate the efficacy and safety of a novel combination therapy using poly-D,L-lactic acid (PDLLA) with autologous fat transplantation for infraorbital rejuvenation.

Correction of Facial Asymmetry Using Dermal Fillers: Understanding the Role of Facial Rotation.

Facial asymmetry is a common challenge in esthetic medicine, requiring a comprehensive understanding of three-dimensional rotation patterns-X, Y, and Z axes-that significantly influence treatment outcomes. Traditional correction methods often overlook these rotational dynamics. This manuscript presents a case study of a 38-year-old Asian male patient with facial asymmetry, treated with hyaluronic acid (HA) fillers using a novel approach incorporating facial rotation concepts.

Treatment of Postinflammatory Hyperpigmentation Following Acne With Microneedling and Panax Ginseng-Derived Exosomes.

This case report evaluated the efficacy of microneedling therapy system (MTS) combined with topical exosome therapy for the treatment of postinflammatory hyperpigmentation (PIH) following acne. Two patients were included in the study: a 32-year-old woman with scattered PIH on her forehead, cheeks, nose, and perioral area, and a 37-year-old man with hyperpigmentation on both cheeks. Both patients underwent 3 sessions of MTS spaced 3 weeks apart, followed by the immediate application of a topical exosome (P198 RECORE SB PLUS, P198 ExoNature, Primoris International Co.

Hypothetical Role of Multiwavelength Diode Laser (755, 808, and 1064 nm) in Addressing Bony Resorption in Facial Aging: A Clinical Commentary.

Background: Facial aging involves not only soft tissue laxity but also progressive bony resorption, particularly in the maxilla and mandible. Current non-invasive aesthetic modalities primarily target soft tissues, neglecting skeletal changes that contribute to volume loss and structural descent.

Objective: To propose the hypothetical role of multiwavelength diode laser (MWDL) in stimulating osteogenesis via controlled thermal delivery to the periosteum, offering a novel, non-invasive strategy for counteracting facial bone resorption.

Alternative Laser Treatment Protocol for Bruise Management.

Background: Post-procedural ecchymosis can last up to two weeks and diminish patient satisfaction. Laser-assisted clearance is documented with pulsed-dye devices, but data on 1064-nm picosecond/nanosecond platforms remain sparse.

Objective: To evaluate a staged 1064-nm laser protocol for accelerating bruise resolution after dermal filler injections.

Anatomical Consideration for Double Chin Thread Lifting.

Background: Thread lifting is a popular minimally invasive option for correcting submental fullness. Given the complex anatomy and multifactorial causes of double chin deformity, anatomical understanding is critical for safe and effective treatment. This study outlines key anatomical considerations and procedural strategies for optimal outcomes in double chin thread lifting.

Shoulder Aesthetics: A Novel Synergy of Calcium Hydroxylapatite Fillers and Neuromodulators.

Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.

The Efficacy of Combined Exosome (Exodew) and Microneedling Treatment for Facial Pore Reduction and Skin Texture Improvement.

Background: Enlarged facial pores are a common aesthetic concern that worsens with age due to increased sebum production, reduced skin elasticity, and photoaging. Although microneedling is known to stimulate collagen production, the combined use of stem cell-derived exosome therapy for pore reduction has not been thoroughly investigated.

Methods: A case series was conducted at a private aesthetic clinic between January and June 2024.

The Efficacy of Combined Microneedling and Topical Poly-d,l-lactic Acid (Juvelook) Application for Facial Pore Reduction and Skin Texture Improvement.

Background: Enlarged facial pores are a common cosmetic concern influenced by factors such as age, genetics, and increased sebaceous activity. Despite the availability of numerous treatment modalities, results are often variable, and many methods involve significant discomfort or a high number of sessions. This case series evaluated the efficacy of combining microneedling with the topical application of poly-d,l-lactic acid (PDLLA, Juvelook, VAIM Inc.

A Novel Approach for Facial Slimming Using Injectable Ascorbic Acid and Ferrous Gluconate: A Case Report.

Minimising facial adiposity is a growing esthetic concern for individuals seeking a slimmer facial appearance. While various surgical and nonsurgical approaches have been used, innovative methods for noninvasive facial contouring continue to emerge. This report presents a case of facial slimming utilising a novel injectable solution comprising ascorbic acid and ferrous gluconate, prepared in a 1:9 ratio.

Efficacy and Safety of High-Intensity Focused Ultrasound (HIFU) on Reduction of Unwanted Submental Fat in Asian Patients.

Background: There are several treatment options to improve a double chin, such as contour injections, thread lifting, and double chin liposuction. However, the results of these treatments can be minimal or have a short-lasting effect. Additionally, these treatments may lead to worsened scarring due to repeated skin penetration and can cause prolonged discomfort.

A Novel Subclassification of Type 2 Dermal Insertion Structures.

Background: Current anatomical classifications inadequately represent dermal insertion structures critical to facial movement, support, and aesthetic outcomes. Particularly, Type 2 structures-defined by direct connections to the dermis-lack precise subclassification.

Objective: To introduce and validate a novel subclassification system for Type 2 dermal insertion structures based on their origin, composition, and clinical relevance in aesthetic and reconstructive procedures.

Exosome-Based Topical Therapy for Facial Atopic Dermatitis.

Background: Atopic dermatitis (AD) is a chronic inflammatory skin condition that significantly impairs quality of life. Current therapies, including corticosteroids and calcineurin inhibitors, often provide incomplete relief or have undesirable side effects. Exosome-based therapies derived from adipose-derived mesenchymal stem cells (ADMSCs) offer a novel, multifaceted approach to addressing inflammation, skin barrier dysfunction, and pruritus, presenting a promising alternative for AD management.

Volumetric Restoration and Lifting of the Lateral Face Using Polycaprolactone-Based Filler.

Aging is associated with volume loss in the temporal fat pad and lateral cheek fat, leading to sunken temples and increased facial sagging. This study explores the efficacy of a polycaprolactone (PCL)-based filler (Lafullen, Samyang, Seoul, Korea) in restoring volume and providing a lifting effect to the lateral face. Four cases were treated with 3 cc of diluted Lafullen (1 cc Lafullen+2 cc normal saline) per side, injected into the interfacial layer (superficial musculoaponeurotic system and superficial temporal fascias).

Anatomical Considerations for Hyaluronic Acid Filler Injection for Breast Augmentation in Young Female Patients.

Hyaluronic acid (HA) fillers offer a minimally invasive alternative for breast augmentation, appealing to young female patients seeking natural results and minimal recovery time. However, achieving optimal outcomes requires a thorough understanding of breast anatomy, filler properties, and safe injection techniques. This study provides a comprehensive analysis of the anatomical considerations, techniques, and filler properties necessary for optimal breast augmentation using HA filler.

Advancements in Clinical Utilization of Recombinant Human Collagen: An Extensive Review.

Introduction: Recombinant human collagen, developed through advanced recombinant DNA technology, has emerged as a cutting-edge biomaterial with diverse applications in medicine. It addresses significant limitations of animal-derived collagens, such as immunogenicity and the risk of zoonotic diseases.

Objective: This review evaluates the clinical applications, benefits, and challenges associated with recombinant human collagen, focusing on its potential to transform medical and surgical practices.

Lactobacillus-Derived Exosome Therapy for Active Acne Vulgaris, Post-Inflammatory Hyperpigmentation, and Atrophic Scarring.

Background: Acne vulgaris often leads to post-inflammatory hyperpigmentation (PIH) and atrophic scarring, affecting patients' quality of life. Traditional treatments may have side effects and inconsistent efficacy. An imbalance in the skin microbiome, particularly a deficiency in Lactobacillus species, has been implicated in acne pathogenesis.

The Yonsei Point: A Precision Approach to Gummy Smile Correction With Botulinum Neurotoxin.

Background: A gummy smile, or excessive gingival display (EGD), is a condition characterized by the visibility of more than 3 mm of gingiva during smiling. It often stems from hyperactivity of the lip elevator muscles, a treatable etiology. Botulinum neurotoxin (BoNT) offers a minimally invasive option for addressing this issue.

Conditions to Consider When Choosing Fillers.

Background: The selection of dermal fillers in aesthetic medicine often relies on factors such as cost, immediate outcomes, and practitioner experience. However, incorporating knowledge of fillers' rheological properties, such as viscoelasticity and cohesiveness, allows for more precise product selection tailored to patient needs and treatment goals while reducing the risk of complications.

Aims: This review aims to summarize essential considerations for filler selection, focusing on rheological properties, safety profiles, and clinical applications.

Considerations for Proper Use of Hyaluronidase in the Management of Hyaluronic Acid Fillers.

Effective management of complications from hyaluronic acid (HA) fillers is crucial in aesthetic medicine. This article examined the role of hyaluronidase in addressing adverse effects associated with HA fillers, such as nodules, vascular occlusions, and excessive volume. It highlights the enzyme's ability to degrade HA, thereby resolving issues that may arise from filler treatments.