High-Detectivity Organic Photodetector with InP Quantum Dots in PTB7-Th:PCBM Ternary Bulk Heterojunction.

Organic photodetectors (OPDs) offer considerable promise for low-power, solution-processable biosensing and imaging applications; however, their performance remains limited by spectral mismatch and interfacial trap states. In this study, a highly sensitive polymer photodiode was developed via trace incorporation (0.8 wt%) of InP/ZnSe/ZnS quantum dots (QDs) into a PTB7-Th:PCBM bulk heterojunction (BHJ) matrix.

Optimized Coil Design for Enhanced Electric Field Induction in Peripheral Nerve Stimulation.

Peripheral nerve electrical stimulation is widely used for the treatment of neuropathic pain and neural regeneration. However, it often induces adverse biological reactions and unintended activation of surrounding neural tissues. As an alternative, peripheral nerve magnetic stimulation offers a promising, less invasive approach that enables targeted nerve stimulation without direct tissue contact.

Intronic miR-342 is a key regulator of cellular glycolysis in Foxp3+ regulatory CD4 T cells.

Foxp3+ regulatory T (Treg) cells are a subset of CD4 T cells that play a potent and indispensable role in regulating immunity and tolerance. The precise mechanisms by which Treg cells mediate such functions have extensively been explored, and there are many cellular and molecular factors that are instrumental for adequate Treg cell functions. microRNAs, small noncoding RNA molecules, are one of the factors capable of regulating Treg cell functions.

Neurotoxic effects of endosulfan on zebrafish (Danio rerio): Cognitive impairments, metallomic alterations, and impact of donepezil treatment.

Endosulfan is classified as a persistent organic pollutant with a ban on use globally, yet it continues to be detected in various environmental compartments. In this study, we used technical endosulfan (with a 7:3 ratio of α-endosulfan to β-endosulfan) to assess its neurotoxic effects on aquatic organisms, particularly adult zebrafish (Danio rerio). Adult zebrafish were exposed to concentrations ranging from 0 to 2.

Acceptability of an Intervention to Prevent Older Adult Mistreatment Among Family Caregivers to Persons With Dementia: Multimethod Pilot Study.

Background: Older adult mistreatment occurs in many as one-half of dementia care partners. Psychological mistreatment is the most common form of older adult mistreatment by family caregivers and is known to create mental health morbidities among care recipients. The Knowledge and Interpersonal Skills to Develop Enhanced Relationships (KINDER) intervention is among the first older adult mistreatment prevention interventions focused on family caregivers.

Observers' gender and behavioral responses to workplace sexual harassment via empathy: The moderating role of organizational intolerance.

Despite the well-established gendered nature of sexual harassment, with women predominantly targeted, it remains unclear whether men and women observers exhibit different behavioral responses to workplace sexual harassment, and if so, why. Given the significant role of observers' actions, understanding how and under which conditions gender influences their positive and negative behaviors has theoretical and practical importance. Drawing on the social role theory of gender, this research examines the relationships between observers' gender and their behavioral responses-intervention, not hearing, and silencing the target-through empathy toward targets.

In-body current path manipulation with minimal attenuation.

Wireless power transfer-based neuromodulation has emerged as a promising alternative to battery-powered implants. However, its practical application is hindered by limited therapeutic efficacy resulting from low power transfer efficiency, shallow penetration depth, and safety concerns. In this study, we report an in-body current path manipulation and concentration for advanced targeted neuromodulation, overcoming the limitations of conventional technologies.

Imitation of Hybrid Cultured Meat Patty and Compare the Quality Characteristics with Beef Patty and Plant-Based Patty.

Limited quantity of cultured meat (CM) production in the laboratory restricts the opportunity for product development and quality assessment. As myofibrillar protein (MFP) possesses similar characteristics to CM, this study used MFP as an imitation of CM to produce an imitated hybrid cultured meat patty (IHCMP) to compare physicochemical and sensory qualities with beef meat patty (BMP) and plant-based meat patty (PBMP). Additionally, dry-aged beef crust was added to improve the taste characteristics of IHCMP and PBMP.

Rapid and sensitive detection of alkaline phosphatase based on fluorescent gold nanoclusters and p-nitrophenyl phosphate.

Alkaline phosphatase (ALP) is an essential enzyme that is involved in various metabolic processes. Abnormal ALP levels are linked to diseases and pathological conditions. Herein, a simple and sensitive assay is reported for ALP detection by using glutathione-conjugated gold nanoclusters (GSH-AuNCs) and p-nitrophenyl phosphate (pNPP), based on the fluorescence quenching mechanism.

(Maitake) extract as natural antioxidant on emulsion-type pork sausages.

This study examined the potential of extract (GF) as a natural antioxidant and functional ingredient in emulsion-type pork sausages. GF demonstrated dose-dependent radical scavenging activity in DPPH and ABTS assays, with a concentration of 5 mg/mL achieving effects similar to those of l-ascorbic acid. Total phenolic and flavonoid contents were 34.

3AIM-seq: Quality assessment of mRNA therapeutics using sequencing for 3' poly(A) tails of in vitro-transcribed mRNA.

In vitro-transcribed (IVT) mRNA therapeutics are promising for preventing and treating diseases, including infectious diseases and cancer, by delivering nucleic acid sequences. Assessing the stability of mRNA sequences and poly(A) tail length is crucial to minimize adverse effects and ensure drug efficacy. However, accurately measuring long homopolymeric nucleotides remains technically challenging, and a specialized method for IVT mRNAs is lacking.

Roles of spin-state dangling bonds and strain in the electronic structure of polytetrafluoroethylene for charge transfer from first-principles.

Utilizing first-principles density functional theory, we computed the surface electronic structure of a polytetrafluoroethylene (PTFE) slab with various dangling bond (DB) configurations. As the number of surface DBs increases, the lowest unoccupied level (LUL) associated with electron affinity (EA) decreases, resulting in a rise in the DBs' formation energy, indicating an unstable state and electron deficiency. Particularly in spinless DB states, only one localized lowest unoccupied surface state (LUSS) forms below the conduction band minimum (CBM).

KoCVAM-led validation of KeraSkin™ Phototoxicity Assay for inclusion in OECD TG 498.

Phototoxicity (or photoirritation) is defined as an acute toxic response elicited by topically or systematically administered photoreactive chemicals after the exposure of the body to environmental light. Korean Center for the Validation of Alternative Methods (KoCVAM) developed and optimized an in vitro phototoxicity test method using KeraSkin™, a reconstructed human epidermis model (RhE), (KeraSkin™ Phototoxicity Assay) as a 'me-too' test method in a previous study. KeraSkin™ Phototoxicity Assay was added to the OECD Workplan for inclusion in OECD test guideline (TG) 498.

Synergistic Integration of Laser Oxidation and Long Short-Term Memory for Advanced Odor Classification in Next-Generation Artificial Olfactory Systems.

Emulating and enhancing human olfactory capabilities, artificial olfactory technology provides adept detection of subtle odors, gases, and various chemical substances. Metal oxide semiconductors (MOSs) are ideal materials for next-generation artificial olfactory devices due to their outstanding gas sensing performance, characterized high sensitivity, high response speed, and robust stability, as well as their compatibility with microfabrication. For broader applications, developing a comprehensive database of diverse odorants is crucial, which necessitates expanding the types of MOS channels in artificial olfactory devices.

PDH Inhibition in Ameliorates Sensory Dysfunction Induced by Vincristine Treatment in the Chemotherapy-Induced Peripheral Neuropathy Models.

Chemotherapy-induced peripheral neuropathy (CIPN) is a significant dose-limiting side effect of many effective anticancer agents, including vincristine. While CIPN adversely affects both oncological outcomes and the quality of life for cancer patients, the in vivo mechanisms behind CIPN pathology remain largely unknown, and effective treatments have yet to be developed. In this study, we established a novel model of CIPN using vincristine to explore the molecular mechanisms underlying this condition.

egg extract improves porcine oocyte quality by decreasing oxidative stress.

This study aimed to assess the influence of egg extract (POEE) treatment on the maturation and development of porcine oocytes subjected to oxidative stress during maturation (IVM). POEE, notably rich in vitamin B9 (folic acid [FA]), was assessed alongside FA for antioxidant activity across various concentrations. In the 650 ppm POEE (650 POEE) group, there was a significant rise in glutathione (GSH) levels and an improved developmental rate in porcine oocytes experiencing oxidative stress during IVM.

Reversible Protein Labeling via Genetically Encoded Dithiolane-Containing Amino Acid and Organoarsenic Probes.

Conventional protein labeling techniques often rely on irreversible covalent bonds, limiting dynamic control over protein modifications. Here, we present a reversible protein labeling strategy using genetically encoded dithiolane-containing amino acid (dtF) and organoarsenic conjugation chemistry. Using dithiarsolane dicarboxylic acid probe A2, we achieved near-quantitative labeling and ethanedithiol-mediated removal within 1 h at room temperature.

GC-MS/MS-based multiresidue pesticide analysis in mealworm () larvae: Optimization of standard QuEChERS-based method to minimize matrix effects.

Given the unsuitability of the standard quick, easy, cheap, effective, rugged, and safe (QuEChERS)-based method for multiresidue pesticide analysis in mealworm larvae due to their complex composition and high lipid content, we established a gas chromatography-tandem mass spectrometry-based procedure for the detection and quantitation of 247 pesticides in this matrix. The optimized extraction solvent (0.1 % formic acid in acetonitrile) was combined with the original QuEChERS salt packet to achieve high recovery rates, and matrix-derived interferents were effectively removed without analyte loss using primary secondary amine-based dispersive solid-phase extraction (cleanup step).

Physicochemical and Sensory Characteristics of Hybrid Flexitarian Pork Loin Steak Combined with Different Plant Ingredients.

This study intended to assess the impacts of the following plant ingredients as treatment named 2.5% alginate paste (TAG), carrot (TRC), red cabbage (TCA), chickpea (; TCP), and included in pork loin meat to produce hybrid meat steak (HBM) to provide healthy meat products suitable for the flexitarian consumers. Plant ingredients were added to the treatment groups at 30%.

Taxonomic Revision of Korean Saddle Fungi (, Helvellaceae).

, commonly known as saddle fungi, is a genus in the Helvellaceae family and is distributed globally. Recent comprehensive studies on have revealed that some species exhibit endemic traits and that many morphologically similar, cryptic species are phylogenetically distant. In this study, 202 Korean specimens collected between 1986 and 2023 were reevaluated through morphological analysis and phylogenetic characterization using barcode sequences, including nrLSU (nuclear Large Subunit Ribosomal DNA), (Heat Shock Protein 90), and ITS (Internal Transcribed Spacer).

Which pathway of the possible sarcopenia algorithm of the AWGS 2019 guideline is the best in Korean community-dwelling older men and women?

Objective: To compare the diagnostic accuracy of possible sarcopenia identification pathways, as suggested by Asian Working Group for Sarcopenia (AWGS) in 2019, by gender among Korean community-dwelling older adults.

Design: Cross-sectional analysis of data from 2,129 community-dwelling adults (70-84 years, 50.4% men) enrolled in Korean Frailty and Aging Cohort Study.

Development of Genomic Simple Sequence Repeat Markers for Evaluating Resources of and Their Transferability to .

In this study, we aimed to develop simple sequence repeat (SSR) markers for evaluating resources in and examine their transferability to related species. SSR markers were developed using the released whole-genome sequence (GenBank assembly accession: GCA_900157425.1).

From Farms to Labs: The New Trend of Sustainable Meat Alternatives.

Meat analogs or meat alternatives mimic conventional meat by using non-meat ingredients. There are several reasons for the rising interest in meat alternatives, e.g.

Techniques and Emerging Trends in Flavor and Taste Development in Meat.

Flavor and taste are critical factors influencing consumer attraction for meat, shaping preferences and commercial demand. This review examines conventional and novel approaches to flavor and taste creation in the meat business, highlighting ways that improve sensory profiles and meet consumer demands. Conventional methods, such as aging and marination, are analyzed in conjunction with new technologies, including enzymatic treatment, fermentation, genetic treatments to alter texture and enhance umami.

Erratum to "An Ultrasoft and Flexible PDMS-Based Balloon-Type Implantable Device for Controlled Drug Delivery".

[This corrects the article DOI: 10.34133/bmr.0012.