Age-friendliness of community and sleep quality: The role of mental health.

Background: The relationship between age-friendliness of community (AFC), mental health and sleep quality is still unclear.

Method: Using a sample of Chinese older adults aged ≥60 years (N = 3099), this cross-sectional study aimed to investigate the serial mediating roles of resilience and depressive symptoms between AFC and sleep quality through structural equation modeling. Additionally, this study examined the association between each AFC dimension and sleep quality stratified by mental health, using the multivariable linear regression models.

Joint effect of testosterone and neurofilament light chain on cognitive decline in men: The Shanghai Aging Study.

Introduction: The association of testosterone and cognitive decline is inconclusive, and its joint effect with neurofilaments light chain (NfL) remains largely unknown.

Methods: A total of 581 non-demented older men in the Shanghai Aging Study were included. Blood total testosterone (TT), free testosterone (FT), and NfL were measured at baseline.

Sex steroid and cognitive function among community-dwelling older men with or without vascular risk factors: a cross-sectional study.

Background: The relationship of testosterone and estradiol concentrations with cognitive function among community-dwelling older men was inconclusive. To examine the association of serum testosterone and estradiol concentrations with cognitive function in older men with or without vascular risk factors (VRFs).

Methods: This cross-sectional study consisted of 224 community-dwelling men aged 65-90 years in the Songjiang District of Shanghai, China.

Weight bearing training alleviates muscle atrophy and pyroptosis of middle-aged rats.

Background: Age-related muscle atrophy and adipose accumulation begin to occur in young and middle-aged individuals, and exercise at an early age improves body composition. Pyroptosis may play an essential role in age-related low-grade inflammation. This study aimed to explore the alleviation of muscle atrophy by weight-bearing training with increasing age inhibition of pyroptosis.

Education level modifies parental hesitancy about COVID-19 vaccinations for their children.

It is important to encourage parental acceptance of children's vaccination against COVID-19 to ensure population immunity and mitigate morbidity and mortality. This study drew upon protection motivation theory (PMT) to explore the factors of parental hesitancy about vaccinating their children. A national online survey was performed in China.