The role of formin-like protein 1 in pancreatic cancer and its specific effects on immunity.

ObjectiveTo investigate the functions and immunological implication of formin-like protein 1 in pancreatic cancer.MethodsA multitude of public datasets and an in-house cohort were used to assess the clinical relevance and the immunological relevance of formin-like protein 1 in pancreatic cancer. Subsequently, in vitro assays were conducted to evaluate the biological roles of formin-like protein 1 in pancreatic cancer and its effects on immunity.

Postoperative Adjuvant Chemoradiotherapy on the Survival of Stage III Gastric Cancer.

Objective: Although adjuvant therapy has been shown to be beneficial in gastric cancer, the use of adjuvant chemoradiotherapy remains controversial. This paper investigated the effects of postoperative adjuvant chemoradiotherapy on the survival of patients with stage III gastric cancer.

Methods: In total, the data of 72 stage III gastric cancer patients treated at our hospital from January 2014 to December 2019 were retrieved and assessed.

Dynamic Changes in the Systemic Inflammation Response Index Predict the Outcome of Resectable Gastric Cancer Patients.

The systemic inflammation response index (SIRI) has been revealed to be closely related to the prognosis of a variety of tumors. Whether the dynamic change in SIRI before and after surgery can be used to judge the prognosis of patients after radical gastrectomy has not yet been studied. In this study, the predictive ability of preoperative SIRI and changes in SIRI before and after surgery for the survival rate of gastric cancer patients was evaluated in two independent cohorts.