Convolutional Long Short-Term Memory network for generating 100 m daily near-surface air temperature.

Global warming and urbanization serve as critical research themes in fine-scale climate studies, particularly in developed cities. This study aims to provide a high spatiotemporal resolution dataset of near-surface air temperatures for densely developed urban areas. The dataset comprises daily maximum, minimum, and mean temperatures for the summer months (June to August) from 2019 to 2023, at a spatial resolution of 100 m, across the Jiangbei climate zone in China.

Vaa3D-x for cross-platform teravoxel-scale immersive exploration of multidimensional image data.

Summary: Vaa3D is a software package that has been widely used to visualize and analyze multidimensional microscopic images in a number of cutting edge bioimage informatics applications. However, due to many recent updates of both software development environments and operating systems, it was highly requested to maintain Vaa3D and disseminate it on latest operating systems. In addition, there has never been a showcase about how to use Vaa3D's cross-platform visualization and immersive exploration functions for multidimensional and teravoxel-scale images.

Paeoniflorin ameliorates neuropathic pain-induced depression-like behaviors in mice by inhibiting hippocampal neuroinflammation activated TLR4/NF-κB pathway.

Neuropathic pain (NP) that contributes to the comorbidity between pain and depression is a clinical dilemma. Neuroinflammatory responses are known to have potentially important roles in the initiation of NP and depressive mood. In this study, we aimed to investigate the effects of paeoniflorin (PF) on NP-induced depression-like behaviors by targeting the hippocampal neuroinflammation through the toll-like receptor 4 (TLR4)/nuclear factor-kappa B (NF-κB) signaling pathway.