Effectiveness of Reso-Pac in enhancing wound healing after third molar surgery: a systematic review with meta-analysis of randomized controlled trials.

Background: Surgical site infections (SSIs) and postoperative complications such as pain, haemorrhage, and nerve damage are significant concerns in oral surgery due to the high bacterial load in the oral cavity. Traditional intraoral dressings, though commonly used, have limitations in effectively preventing infections and promoting wound healing, especially following the surgical extraction of impacted mandibular third molars. Reso-Pac, a self-dissolving hydrophilic wound protection paste, has emerged as a potential solution, offering benefits such as medication delivery, protective barrier functions, and astringent properties.

Effectiveness of oral dextrose gel for neonates at risk of hypoglycemia: A systematic review, meta-analysis, and GRADE assessment of randomized controlled trials.

Neonatal hypoglycemia is the most common metabolic disorder in newborns and can lead to neurological damage if untreated. While intravenous dextrose is the standard treatment, it is invasive. Oral 40% dextrose gel (0.

Ethnicity-based variations in biological reference interval- A systematic scoping review.

Background: Biological reference intervals (RIs) are fundamental tools in clinical diagnostics, traditionally derived from geographically and ethnically homogeneous populations, predominantly of Western origin. Such generalized RIs often fail to account for variations arising from genetic, environmental, and lifestyle factors, which can impact clinical decision-making and contribute to health inequities, particularly in countries across Africa, India, and many other Southeast Asian nations. This scoping review investigates ethnicity-based variations in RIs for a range of biomarkers to highlight the importance of population-specific RIs.

Efficacy of duloxetine in treating temporomandibular joint disorder: a systematic review with bayesian meta-analysis.

Objectives: This study aims to evaluate the efficacy of duloxetine in managing temporomandibular joint disorder (TMD), focusing on pain reduction and functional improvement. The research addresses the need for novel therapeutic agents due to the suboptimal efficacy and tolerability of existing treatments.

Materials And Methods: A systematic review and Bayesian meta-analysis were conducted following PRISMA guidelines.

Efficacy of intralesional platelet-rich plasma versus intralesional corticosteroids in the management oral lichen planus: A systematic review and meta-analysis of randomized controlled trials using random effects and weighted least square methods.

Aim: This systematic review and meta-analysis aimed to compare the efficacy of intralesional platelet-rich plasma and intralesional steroids in managing oral lichen planus, focusing on pain and lesion size reduction.

Methodology: A systematic search of MEDLINE (via PubMed), Web of Science, Scopus, and Embase was conducted up to May 30, 2024, to identify randomized controlled trials (RCTs) comparing the efficacy of intralesional platelet-rich plasma (PRP) and intralesional steroids in managing oral lichen planus (OLP). The study adhered to a predefined PICOS framework: (P) adults diagnosed with OLP, (I) PRP application, (C) steroid application, (O) outcomes related to pain reduction and lesion size, and (S) RCTs.

Weightage Identified Network of Keywords Technique: A Structured Approach in Identifying Keywords for Systematic Reviews.

Objectives: The objective of this study was to develop the weightage identified network of keywords (WINK) technique for selecting and utilizing keywords to perform systematic reviews more efficiently. This technique aims to improve the thoroughness and precision of evidence synthesis by employing a more rigorous approach to keyword selection.

Methods: The WINK methodology involves generating network visualization charts to analyze the interconnections among keywords within a specific domain.

Efficiency of Glucosamine in Treating Temporomandibular Joint Osteoarthritis: A Meta-Analytic Umbrella Review.

Background: Temporomandibular joint osteoarthritis (TMJ OA) is a chronic disease that is a consequence of undue occlusal forces and is characterized by irreversible damage to the articular surfaces. Symptomatic slow-acting so-called nutraceutical drugs have been proposed as a treatment for osteoarthritis in comparison to non-steroidal anti-inflammatory drugs (NSAIDs). Oral glucosamine and chondroitin, slow-acting drugs, have been found to reduce pain and increase mouth opening in patients with TMJ OA.

Effects of Glucosamine in the Temporomandibular Joint Osteoarthritis: A Review.

Osteoarthritis in the temporomandibular joint (TMJ) is a chronic disease characterized by irreversible damage to articular surfaces, including inflammation, loss of articular cartilage, and subchondral bone alterations, which would be radiographically evident only in later stages. Symptomatic slow-acting so-called nutraceutical drugs have been proposed as a treatment for osteoarthritis in comparison to non-steroidal anti-inflammatory drugs (NSAID) because of their appreciable safety profile even in long-term intake. Glucosamine, being one among them, proved highly efficient in knee osteoarthritis.