Publications by authors named "Sarah A Purcell"

Background & Aims: Body composition and energy metabolism (BC and EM) assessments inform patients' nutritional status and allow the identification, diagnosis, and management of core nutritional problems. However, a structured approach or care model for integrating these assessments into the nutrition care process is currently lacking. This manuscript describes the protocol for a planning project aimed at convening a multidisciplinary team of researchers, healthcare providers, provincial managers, and industry partners to identify a practical pathway for implementing BC methods and indirect calorimetry for EM assessment in targeted clinical settings.

View Article and Find Full Text PDF

Breast cancer survivors (BCS) undergoing adjuvant endocrine therapy have increased risk of obesity. Estrogen and exercise suppress appetite in non-BCS populations, but their combined effects in BCS are unknown. This secondary analysis compared the impact of acute resistance exercise (REx) on appetite and energy intake in estrogen-suppressed BCS versus females without cancer ('non-BCS').

View Article and Find Full Text PDF

Field-based sport research involves studies that collect data from athletes and/or teams during competition and/or their daily training environments. Over the last decade, sport-specific field-based research projects have significantly increased in number and complexity, partially owing to the further development of more portable measurement equipment (e.g.

View Article and Find Full Text PDF

Emerging evidence underscores the pivotal role of diet in preventing and managing inflammatory bowel disease (IBD). As our comprehension of the microbiome's role in IBD expands, dietary modifications are increasingly recognized as potential adjuncts or primary therapeutic strategies. Key components of the Mediterranean diet (MD)-including microbiota-accessible carbohydrates, omega-3 fatty acids, polyphenols, and antioxidants-have demonstrated promise in enhancing gut microbiota diversity and reducing intestinal inflammation, making it a practical approach for managing IBD.

View Article and Find Full Text PDF

Background: Energy requirement assessment is a cornerstone for nutrition practice. The extent to which total energy expenditure (TEE; indicator of energy requirements) has been measured in adults with chronic diseases has not been explored.

Objectives: This systematic review aimed to characterize evidence on TEE among individuals with chronic diseases and describe TEE across chronic diseases and in comparison to controls without a chronic disease.

View Article and Find Full Text PDF

Purpose: Metabolic diseases such as diabetes mellitus may play a role in the development and progression of prostate cancer (PC); however, this association remains to be explored in the context of specific PC stages. The objective of this study was to systematically review the evidence for an association between diabetes and overall, early, or advanced PC risk.

Materials And Methods: A systematic review with meta-analysis was performed (MEDLINE, EMBASE, and CINAHL) from inception until September 2023.

View Article and Find Full Text PDF

We tested whether spontaneous physical activity (SPA) from accelerometers could be used in a whole room calorimeter to estimate thermic effect of food (TEF). Eleven healthy participants ( = 7 females; age: 27 ± 4 yr; body mass index: 22.8 ± 2.

View Article and Find Full Text PDF

Background & Aims: Brief screening questionnaires can identify 'at risk' behaviors in clinical settings. However, there is currently no screener for dietary intake specifically developed using foods associated with body weight change and increased risk for multiple chronic conditions and diseases.

Methods: We developed a novel brief dietary screener, the 24-Hour Food Frequency Assessment Screening Tool Questionnaire (FAST24), to identify intake of foods associated with weight change.

View Article and Find Full Text PDF
Article Synopsis
  • Diet is crucial for cancer patients, and organizations like the World Cancer Research Fund International and the American Cancer Society emphasize its role in prevention.
  • A bibliometric analysis of nearly 100,000 publications since 1970 found lots of studies on diet's link to breast, colorectal, and liver cancers, but fewer on others like brain or ovarian cancer.
  • Healthy diet studies mainly focused on the Mediterranean diet and fruits/vegetables, suggesting a need for more research on less-studied cancers and dietary influences during and after cancer treatment.
View Article and Find Full Text PDF

Introduction/purpose: A reduction in nonexercise physical activity (NEPA) after exercise may reduce the effectiveness of exercise interventions on weight loss in adults with overweight or obesity. Aerobic exercise (AEx) and resistance exercise (REx) may have different effects on NEPA. The purpose of this secondary analysis was to examine the effect of a single bout of AEx or REx on NEPA and sedentary behavior in inactive adults with overweight or obesity.

View Article and Find Full Text PDF

Background: Total energy expenditure (TEE) determines energy requirements, but objective data in patients with cancer are limited.

Objectives: We aimed to characterize TEE, investigate its predictors, and compare TEE with cancer-specific predicted energy requirements.

Methods: This cross-sectional analysis included patients with stages II-IV colorectal cancer from the Protein Recommendation to Increase Muscle (PRIMe) trial.

View Article and Find Full Text PDF

Energy balance accounts for an individual's energy intake, expenditure, and storage. Each aspect of energy balance has implications for the pharmacokinetics of cancer treatments and may impact an individual's drug exposure and subsequently its tolerance and efficacy. However, the integrated effects of diet, physical activity, and body composition on drug absorption, metabolism, distribution, and excretion are not yet fully understood.

View Article and Find Full Text PDF

This study compared anthropometric and body fat percent (BF%) equations in relation to measures of metabolic health. BF% calculations (Bergman, Fels, and Woolcott) and anthropometric measurements were used to determine obesity among a sample of patients attending primary care in Alberta, Canada. Anthropometric variables included body mass index (BMI), waist circumference, waist:hip ratio, waist:height ratio, and calculated BF%.

View Article and Find Full Text PDF

Appetite is a determinant of dietary intake and is impacted by sex hormones, exercise, and body composition among individuals without chronic conditions. Whether appetite is altered by exercise in the context of estrogen suppression and cancer survivorship is unknown. This randomized cross-over study compared appetite and ad libitum energy intake (EI) after acute resistance exercise (REx) versus sedentary (SED) conditions and in relation to body composition and resting metabolic rate (RMR) in breast cancer survivors (BCS).

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to compare the effects of dietary restriction (DIET) and aerobic exercise (AEX) on energy balance and appetite in overweight or obese adults over a 12-week period.
  • Both interventions led to weight loss and changes in body composition, but did not significantly differ in their effects on resting metabolic rate, energy intake, or levels of hunger and dietary restraint.
  • While the DIET group saw a decrease in hunger, and the AEX group showed reduced disinhibition, overall, neither intervention produced major differences in appetite or physical activity between the groups.
View Article and Find Full Text PDF

Individuals with cancer may be motivated to make lifestyle changes and informed dietary choices, but are exposed to conflicting and erroneous nutrition information, particularly from online and social media sources. Changes to dietary choices that stem from a diagnosis of cancer are not fully understood. Thus, we conducted a narrative review to summarize the literature focused on dietary choices after a cancer diagnosis, and highlighted influential factors.

View Article and Find Full Text PDF

Background: Yoga may reduce body weight in individuals with overweight or obesity, but whether this occurs through decreased energy intake (EI) or increased energy expenditure (EE)/physical activity (PA) is unclear.

Methods: A systematic search of PubMed, Web of Science, Embase, and PsychINFO was conducted from inception until April 26, 2021. Eligible studies included randomized controlled trials or single-arm pre-post studies with any type and duration of yoga intervention in adults with overweight or obesity.

View Article and Find Full Text PDF

The purpose of this study was to evaluate the feasibility and acceptability of randomizing adults with overweight and obesity (BMI 25-40 kg/m) to morning (06:00-10:00) or evening (15:00-19:00) aerobic exercise. Participants completed four exercise sessions per week in the morning (AM, = 18) or evening (PM, = 15). The exercise program was 15 weeks and progressed from 70 to 80% heart rate maximum and 750-2000 kcal/week.

View Article and Find Full Text PDF

Body composition parameters are not captured by measures of body mass, which may explain inconsistent associations between body weight and prostate cancer (PC) risk. The objective of this systematic review was to characterize the association between fat mass (FM) and fat-free mass (FFM) parameters and PC risk. A search of PubMed, Embase, and Web of Science identified case-control and cohort studies that measured body composition in relation to PC risk.

View Article and Find Full Text PDF

Many breast cancer survivors (BCS) gain fat mass and lose fat-free mass during treatment (chemotherapy, radiation, surgery) and estrogen suppression therapy, which increases the risk of developing comorbidities. Whether these body composition alterations are a result of changes in dietary intake, energy expenditure, or both is unclear. Thus, we reviewed studies that have measured components of energy balance in BCS who have completed treatment.

View Article and Find Full Text PDF

Sarcopenic obesity is associated with several negative health outcomes. However, the prevalence of this condition - and the relationship to physical performance parameters - varies across definitions. The aim of this cross-sectional investigation was to describe the prevalence of sarcopenic obesity using different published definitions and their relationship with handgrip strength and walking speed in older Canadian adults.

View Article and Find Full Text PDF

Background And Aims: The accuracy of some portable indirect calorimeters in estimating resting energy expenditure (REE) - and hence energy recommendations - among pre-bariatric patients is unknown. Our objective was to assess the accuracy of the MedGem® among individuals with class II or III obesity awaiting bariatric surgery.

Methods: Male and female adults who were awaiting bariatric surgery were recruited to this cross-sectional study.

View Article and Find Full Text PDF

Background/objectives: Resting energy expenditure (REE) is the largest component of total energy expenditure. As such, inaccurate estimation or measurement of REE may impact the development of individualized energy intake recommendations. The objective of this observational study was to assess the accuracy and reliability of REE measured with a portable indirect calorimeter with ventilated hood - Fitmate GS - compared to REE from whole-body indirect calorimetry (WBC).

View Article and Find Full Text PDF

Many patients with cancer experience poor nutritional status, which detrimentally impacts clinical outcomes. Poor nutritional status in cancer is primarily manifested by severe muscle mass (MM) depletion, which may occur at any stage (from curative to palliative) and often co-exists with obesity. The objective of this article was to discuss gaps and opportunities related to the role of nutrition in preventing and reversing low MM in cancer.

View Article and Find Full Text PDF