Publications by authors named "Sandesh Sharma"

Data on acute mesenteric ischaemia (AMI) in patients with Covid-19 are limited. We studied the clinical profile and outcome of patients presenting and treated for AMI and Covid-19 infection. This retrospective, observational study was done at a single tertiary care centre in India from May 2021 to April 2022.

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Article Synopsis
  • The growing demand for skilled workers in healthcare highlights the importance of higher education in addressing the skills gap for better economic outcomes.
  • Universities are creating programs that enhance critical thinking, communication, and teamwork, while also collaborating with employers to meet specific job requirements.
  • The paper discusses how educational institutions can support the healthcare sector by fostering industry partnerships, updating curricula, and providing ongoing professional development for workers.
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Background: In the Visakhapatnam District, this study compares the quality management procedures used by public and private hospitals. Knowing how these practices are similar and different from one another can help inform policy decisions and improve the quality of health care.

Materials And Methods: A cross-sectional study design was used, and 100 hospitals from both public (50 hospitals) and private (50 hospitals) were included in the sample size.

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Article Synopsis
  • - Nail-patella syndrome (NPS) is a rare genetic disorder characterized by skeletal deformities and various other health issues, such as renal failure and heart problems.
  • - A 17-year-old male patient exhibited multiple skeletal abnormalities, advanced renal failure, hypothyroidism, and dilated cardiomyopathy, leading to a clinical diagnosis of NPS supported by imaging and biopsy findings.
  • - The association of dilated cardiomyopathy with NPS is not well-documented, highlighting the importance of a thorough evaluation due to the disorder's diverse systemic effects.
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Myasthenia gravis (MG) is an autoimmune illness that causes neuromuscular junctions to be damaged by anti-acetylcholine receptor antibodies. It is a very rare condition that is more common among women. Fatigable fluctuating diplopia or ptosis is the characteristic early appearance of this condition.

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It is very rare to find large gastrointestinal stromal tumors arising from the gastrohepatic omentum in a patient with neurofibromatosis type 1. We here document a case of two large gastrointestinal stromal tumors arising from the gastrohepatic omentum in a patient with von Recklinghausen's disease. In the present case, two large tumors in the lesser sac were evident on preoperative computed tomography and magnetic resonance imaging and were surgically removed successfully.

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Fecal colo-cutaneous fistula often requires surgical intervention for successful closure increasing the morbidity and mortality associated with this condition. Endoscopic fistula closure can be a less invasive modality. We report successful closure of fecal colo-cutaneous fistula by endoscopic application of metal hemo-clips after failure of prolonged treatment including diverting proximal ileostomy in 2 consecutive patients after emergency primary repair of cecal perforation caused by stab injury of abdomen and iatrogenic fecal fistula after left hemicolectomy and colo-colic anastomosis for adenocarcinoma of descending colon, respectively.

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Background/aims: Radiofrequency has been used recently for bloodless liver resection. We studied the safety and feasibility of using RF energy for liver parenchymal transection in 8 patients.

Methodology: We performed eight (n=8) open RF assisted liver resection for various malignancies.

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Background/aims: Pancreatic carcinoma is by far the most common malignancy and is the 5th most lethal cancer in the world and 40% of these carcinomas are locally advanced and unresectable at the time of presentation. Palliative surgery and chemoradiotherapy have not produced significant improvement in survival. The overall prognosis of these pancreatic cancers is poor, if left untreated without any form of palliation.

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Primary tumors arising from great vessels like the aorta, pulmonary artery or inferior vena cava (IVC) are rare. The latter is the commonest site of its occurrence. It arises from the smooth muscle cells of the vessel wall.

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Transitional cell carcinoma arises from the lining of the urogenital tract and ovary. We report a 39-year-old lady with transitional cell carcinoma of the spleen that presented as a complex cystic lesion. Exhaustive search for another primary was negative.

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Background: Orally administered gastrografin has been used for early resolution of postoperative small bowel obstruction (POSBO) and to reduce the need for surgery in various studies. However the studies have reported conflicting results as patients with complete obstruction and equivocal diagnosis of bowel strangulation were also included.

Patients And Methods: We carried out a prospective study to evaluate the efficacy of gastrografin in patients with partial adhesive small bowel obstruction.

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Context: Unresectable pancreatic cancer has a dismal prognosis. Palliative surgery and chemo-radiotherapy have not produced significant improvement in survival. We evaluated the safety and the efficacy of radiofrequency ablation for cytoreduction of unresectable tumors of the pancreas.

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Background: Sclerosing pancreatitis is an autoimmune condition characterized by periductal lymphocytic infiltration on histology, and elevated serum auto-antibodies and IgG4. Bile duct involvement is often associated with sclerosing pancreatitis but it is rarely the dominant feature.

Case Report: We report a patient with dominant biliary stricture and obstructive jaundice associated with IgG4 negative autoimmune pancreatitis.

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Context: Squamous cell carcinoma of the biliary tree is rare. Although few cases of squamous cell carcinoma of the intrahepatic bile-duct and gallbladder have been reported, until today, only four cases of squamous cell carcinoma of the extrahepatic bile duct have been reported in the literature.

Case Report: We present a case of squamous cell carcinoma of the distal common bile duct presenting with obstructive jaundice in a 60-year-old male which was successfully managed by a Whipple's pancreaticoduodenectomy.

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Introduction: Radiofrequency (RF) tissue ablation has been tried safely and effectively in the West as percutaneous local tissue ablation therapy. We present our experience with this technique in malignant lesions.

Methods: RF tumor ablation was done using an RF generator (Berchtold; Germany) generating 35-50 RF watts of power output.

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