Publications by authors named "Sanchit Kumar"

Small streams in the large river basins are disappearing, and there is no update on their historical and current morphometric status. Field inventory and visual inspections quantified the impact of land use and land cover (LULC) change on the reference year morphometry (1970-1977) of seven watersheds and fifty-six subwatersheds, using drone imagery and Global Positioning System-based ground control points to refine the reference map and generate the current map (2021-2024). The decreasing stream number (Nu), stream length (Lu), and drainage density (Dd) (1) explained the mechanism of disappearing and shrinking large rivers; (2) classified seven watersheds and fifty-six subwatersheds into near threatened (NT), vulnerable (VU), endangered (EN), critically endangered (CR), and extinct (EX) categories; and (3) emphasized rejuvenation of 9,84,068 km of lost streams to restore Dd ≥ 2 km/km in the Ganga River basin (GRB).

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NiRX (R = aryl, alkyl; X = halogen) complexes containing bipyridine (bpy)-type ligands play a crucial role in metallaphotoredox-catalyzed cross-coupling reactions. Despite the excited-state dissociation of Ni-C and Ni-halide bonds in the (bpy)Ni(aryl)(halide) complex being well understood, the corresponding (bpy)Ni(alkyl)(halide) complex remains largely unexplored. Experimentally, it is challenging due to its instability, making isolation and characterization difficult and necessitating computational investigations.

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The mechanism of visible light-driven Ni-C(aryl) bond homolysis in (2,2'-bipyridine)Ni(aryl)(halide) complexes, which play a crucial role in metallaphotoredox catalysis for cross-coupling reactions, has been well studied. Differently, the theoretical understanding of Ni-halide bond homolysis remains limited. In this study, we introduce a novel electronic structural framework to elucidate the mechanisms underlying photoinduced Ni-Br bond rupture in the (dtbbpy)Ni(aryl)(Br) complex.

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Introduction: Screening for atrial fibrillation (AF) in the general population may help identify individuals at risk, enabling further assessment of risk factors and institution of appropriate treatment. Algorithms deployed on wearable technologies such as smartwatches and fitness bands may be trained to screen for such arrhythmias. However, their performance needs to be assessed for safety and accuracy prior to wide-scale implementation.

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Background: Lipid-lowering therapy (LLT) is underutilized for very high-risk atherosclerotic cardiovascular disease. PROMPT-LIPID (PRagmatic Trial of Messaging to Providers about Treatment of HyperLIPIDemia) sought to determine whether electronic health record (EHR) alerts improve 90-day LLT intensification in patients with very high-risk atherosclerotic cardiovascular disease.

Methods: PROMPT-LIPID was a pragmatic trial in which cardiovascular and internal medicine clinicians within Yale New Haven Health (New Haven, CT) were cluster-randomized to receive an EHR alert with individualized LLT recommendations or no alert for outpatients with very high-risk atherosclerotic cardiovascular disease and LDL-C (low-density lipoprotein cholesterol), ≥70 mg/dL.

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Importance: COVID-19 infection is associated with a high incidence of acute kidney injury (AKI). Although rapid kidney function decline has been reported in the first few months after COVID-19-associated AKI (COVID-AKI), the longer-term association of COVID-AKI with kidney function remains unknown.

Objective: To assess long-term kidney outcomes of patients who had COVID-19-associated AKI.

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Article Synopsis
  • * Although there was no significant difference in the time it took for kidney function to recover between those who received SGLT2i and those who did not, using SGLT2i did not worsen patients’ conditions.
  • * This research involved 3,305 hospitalized adults with AHF and AKI, and the effects were analyzed using advanced statistical methods to ensure the reliability of results.
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Unlabelled: Since the authors are not responding to the editor’s requests to fulfil the editorial requirement, therefore, the article has been withdrawn from the journal "Infectious Disorders - Drug Targets" Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.

Bentham Science Disclaimer: It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere must be reported, and copyright permission for reproduction must be obtained.

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The ecological conservation of large rivers is impossible unless immediate attention is given to protecting their small tributaries at local levels. The natural boundaries of large river basins are shrinking because their tributaries and streams of different orders are disappearing at an unprecedented rate. Delineation of the fixed administrative boundaries (AB) to protect the natural boundary of small rivers and their classification into appropriate threatened categories, the present study was carried out on the 54.

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Wearable devices stand to revolutionize the way healthcare is delivered. From consumer devices that provide general health information and screen for medical conditions to medical-grade devices that allow collection of larger datasets that include multiple modalities, wearables have a myriad of potential uses, especially in cardiovascular disorders. In this review, we summarize the underlying technologies employed in these devices and discuss the regulatory and economic aspects of such devices as well as the future implications of their use.

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Literature is lacking on the spectrum of symptoms of long COVID-19 (defined as symptoms persisting beyond 28 days of diagnosis) and its impact on quality of life. This single-center, cross-sectional study included mild COVID-19 cases as determined by a positive real-time reverse transcription polymerase chain reaction test. Patients were contacted at least 28 days after diagnosis and were interviewed telephonically using semi-structured questionnaires for duration of symptoms, fatigue using Fatigue Severity Scale (FSS) and quality of life using the World Health Organization Quality of Life: Brief Version (WHOQOL-BREF).

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Article Synopsis
  • The study investigates the impact of mobile phone usage on sleep quality and duration among a sample of the Indian population.
  • Conducted in north India from 2014 to 2019, it involved 566 participants, with assessments via the Pittsburgh Sleep Quality Index and other sleep monitoring techniques.
  • Findings revealed that higher mobile phone use is linked to poorer sleep quality and shorter times to reach deeper sleep stages, suggesting that mobile usage negatively affects sleep patterns.
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  • The study examined the characteristics and treatment outcomes of patients with extra-pancreatic IgG4-related disease (IgG4-RD) at a tertiary care center in northern India over four years.
  • A total of 14 patients were identified, mostly middle-aged males, presenting with soft tissue swellings and experiencing significant delays in diagnosis.
  • Treatment with prednisolone yielded positive results, with over 40% of patients successfully tapering off corticosteroids, highlighting the need for increased awareness among healthcare providers for early diagnosis and management of this condition.
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The quantum dynamics of rotational transitions of the diisocyanogen (CNNC) molecule undergoing collision with the helium (He) atom occurring in the interstellar medium (ISM) has been studied. The rotational deexcitation cross sections are extracted by first computing an potential energy surface of CNNC-He using the coupled-cluster with single and double and perturbative triple excitations with the F12a method (CCSD(T)-F12a) employing the aug-cc-pVTZ basis set. Utilizing the multipole expansions, collisional cross sections are determined for total energies of up to 1000 cm by the close coupling equations.

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Objectives: To study the histopathology of patients dying of COVID-19 using post-mortem minimally invasive sampling techniques.

Methods: This was a single-center observational study conducted at JPNATC, AIIMS. Thirty-seven patients who died of COVID-19 were enrolled.

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: The COVID-19 pandemic has provided global challenges to health-care facilities in ensuring the delivery of care to patients. Tremendous international collaboration has enabled the swift formulation of evidence-based guidelines that aim to clarify day-to-day issues faced by physicians and other health-care providers on the frontlines.: In order to provide answers to the common questions and dilemmas faced by physicians and policymakers, especially those handling pulmonary manifestations of COVID-19, the authors made a list of pertinent clinical topics that were reviewed between 21st of August, 2020 to 30th of August, 2020 by the authors using online databases that included PubMed, EBSCO, and the Cochrane Library.

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The ongoing pandemic of COVID-19 has put an immense strain on healthcare facilities around the world. Unique challenges are being faced in the adequate management of rapidly increasing number of cases while ensuring adequate healthcare providers apostrophe safety. Issues related to the difficulty of examination while wearing personal protective equipment, need for objectivity in triage and testing of patients, and evidence-based management of the critically ill has resulted in reliance on longitudinal radiological assessment.

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Aim: The aim of the present study was to investigate the prevalence and etiology of molar-incisor hypomineralization (MIH) in 8- to 16-year-old children from town (Baddi) of Himachal Pradesh.

Materials And Methods: A cross-sectional study was conducted with 2000 children from various schools of Baddi. Molar-incisor hypomineralization was diagnosed on the basis of EAPD 2003 criteria revised in 2009.

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Purpose: Mycoplasma pneumoniae (M. pneumoniae) and Chlamydophila pneumoniae (C. pneumoniae) play a significant role in children of all ages with lower respiratory tract infections (LRTIs).

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Unlabelled: Dentinogenesis imperfect is a hereditary dentin defect leading to discoloration as well as early tooth wear. Timely diagnosis and treatment are required to prevent further tooth loss. Two patients reported to the department of pediatrics dentistry with dentinogenesis imperfecta (DI).

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Background & Objectives: Respiratory syncytial virus (RSV) and Mycoplasma pneumoniae are considered common cause of lower respiratory tract infections (LRTIs) in children. The present study was conducted to detect M. pneumoniae and RSV in paediatric LRTIs employing serology, polymerase chain reaction (PCR) and reverse transcriptase PCR (RT-PCR) analysis.

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The study presents the spatial and temporal variation of fine ambient aerosols (PM) over National Capital Region (NCR), India, during January to June 2016. The investigation includes three sampling sites, one in Delhi and two in the adjoining states of Delhi (Uttar Pradesh and Haryana), across NCR, India. The average PM concentration was highest for Delhi (128.

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