Outcomes of resuscitative endovascular balloon occlusion of the aorta (REBOA) in severely injured adult trauma patients with isolated thoracic or abdominal trauma in Hemorrhagic shock.

Background: There is conflicting literature regarding mortality outcomes associated with REBOA usage in patients with severe thoracic or abdominal trauma. Our study aims to assess the benefits and negative implications of REBOA use in adult trauma patients in hemorrhagic shock with severe thoracic or abdominal injuries.

Methods: This retrospective cohort analysis utilized the American College of Surgeons Trauma Quality Improvement Program Participant Use File (ACS-TQIP-PUF) database from 2017 to 2023 to evaluate adult patients with severe isolated thoracic or abdominal trauma undergoing REBOA placement.

Nuclear compression-mediated DNA damage drives ATR-dependent Lamin expression and mouse ESC differentiation.

Embryonic stem cells (ESCs), which are susceptible to DNA damage, depend on a robust and highly efficient DNA damage response (DDR) mechanism for their survival. However, the implications of physical force-mediated DNA damage on ESC fate remain unclear. We show that stiffness-dependent spreading of mouse ESCs (mESCs) induces DNA damage through nuclear compression, with DNA damage causing differentiation through Lamin A/C.

A Study on Correlation between Red Cell Distribution Width to Platelet Ratio (RPR) and Child Turcotte Pugh Score in Patients of Chronic Liver Disease at Tertiary Care Center of Jharkhand.

Background: It was hypothesized that high red cell distribution width (RDW) due to anemia and the low platelet count due to cirrhosis studies impacts the RDW to platelet ratio (RPR), which can be used as a predictor of significant fibrosis and cirrhosis. For evaluation of the severity of liver disease Child-Turcotte-Pugh (CTP) score is universally used.

Aims: To determine the correlation between RPR with CTP severity score in patients of chronic liver disease (CLD), and to evaluate the severity of CLD indirectly with RPR.

A Case Report of a 14-year-old Boy with Mixed-type Autoimmune Hemolytic Anemia.

Autoimmune hemolytic anemia (AIHA) is uncommon in the pediatric population, particularly when it manifests as severe anemia. AIHA is characterized by a positive direct antiglobulin test (DAT) and immune-mediated red blood cell (RBC) destruction. AIHA is subclassified on the basis of the thermal characteristics of autoantibody into warm, cold, and mixed.

Emergent Dirac fermions in graphene and underlying Au monolayer with two-dimensional ferrimagnetism.

Using angle-resolved photoemission spectroscopy (ARPES) with spin resolution, scanning tunneling microscopy/spectroscopy (STM/STS) and density functional theory (DFT) methods, we study the electronic structure of graphene-covered and bare Au/Co(0001) systems and reveal intriguing features, arising from the ferrimagnetic order in graphene and the underlying gold monolayer. In particular, a spin-polarized Dirac-cone-like state, intrinsically related to the induced magnetization of Au, was discovered at point. We have obtained a good agreement between experiment and theory for bare and graphene-covered Au/Co(0001) and have proven that both Au ferrimagnetism and the Dirac-cone-like band are intimately linked to the triangular loop dislocations present at the Au/Co interface.