A Case Report of a 14-year-old Boy with Mixed-type Autoimmune Hemolytic Anemia.

Autoimmune hemolytic anemia (AIHA) is uncommon in the pediatric population, particularly when it manifests as severe anemia. AIHA is characterized by a positive direct antiglobulin test (DAT) and immune-mediated red blood cell (RBC) destruction. AIHA is subclassified on the basis of the thermal characteristics of autoantibody into warm, cold, and mixed.

Intraoperative Decision-Making: A Comparative Analysis of Scrape Cytology vs. Frozen Section in Eighty Consecutive Samples.

Introduction: Intraoperative tumor evaluation is essential for optimizing surgical decision-making and can prevent the need for unnecessary radical surgeries. Although frozen section (FS) is the gold standard for such evaluations in advanced centers, scrape cytology presents a simpler, cost-effective alternative that could be beneficial in resource-limited settings. However, this technique is often overlooked in favor of FS due to greater pathologist confidence in FS.

Eco-Friendly Biopolymers: Eco-Friendly Biopolymers: Converting Waste Cooking Oil Into Simultaneous Production of Two Valuable Polyhydroxyalkanoates and Bacterial Alginate Through Microbial Conversion.

An obstacle to the commercial application of polyhydroxyalkanoates (PHAs) and a co-product exopolysaccharide, alginate, is their high production cost. In this study, waste cooking oil (WCO) was used as an inexpensive carbon source for biopolymer production by Pseudomonas mendocina PSU. The highest biomass of 4.

Emerging Trend of Multidrug-resistant Organisms Causing Sepsis in Ventilated Newborns.

Introduction: Increasing trend of antibiotic and multidrug resistance (MDR) organism are significant public health risks and major issues in intensive care unit (ICU). We aimed to identify, determine the prevalence, and to evaluate their antibiotic resistance pattern in sepsis-positive ventilated newborns.

Materials And Methods: The observational cross-sectional study was conducted in a neonatal ICU.

Improving Bioplastic Production: Enhanced P(3HB--3HHx) Synthesis from Glucose by Using Mutant .

Background: Biodegradable polyhydroxyalkanoates (PHAs) hold promises for various applications in industries ranging from packaging to biomedical engineering, highlighting the importance of this pioneering research in sustainable materials synthesis.

Objectives: The objective of this investigation was to present the successful production of polyhydroxyalkanoate (PHA) copolymer P(3HB--3HHx) from glucose utilizing a newly mutated strain of . This mutant strain carries the pBPP-ccrJ-emd plasmid which harbors a short-chain-length-specific PhaJ enzyme.

Water disinfection and disinfection by products.

For ecological safety and public health, it is essential to identify the causes of pollution in water sources and the effects of both natural and human activities. A class of secondary pollutants known as disinfection byproducts (DBPs) is produced when water is treated with disinfectant. Global problems include DBP formation, monitoring, and health effects in drinkable water.

Case report of familial hypercholesterolemia with internal carotid neck swelling.

Familial hypercholesterolemia is a multi-gene disorder affecting 1 in 200-500 individual which is characterized by increased level of total cholesterol and low density lipoprotein (LDL) which deposit cholesterol reach protein leading to xanthomas, corneal arcus and prone to develop risk for atherosclerosis and coronary heart disease. 11 year female, born of consanguineous marriage attended with yellowish patches (Xanthelasma) bilaterally present over upper eyelid, buttock since 5-6 years. In family history younger girl along with both parents has Xanthelasma.

SDN TCP-SYN Dataset: A dataset for TCP-SYN flood DDoS attack detection in software-defined networks.

The TCP-SYNC SDN dataset, a collection of labelled network traffic data for investigating DDoS attack detection in Software-Defined Networking (SDN) environments. The dataset includes flow-level metrics from both normal and malicious traffic, particularly TCP-SYN flood attacks. Generated in a controlled testbed using advanced simulation tools Mininet(v2.

A sustainable and green method for controlling acidic corrosion on mild steel using leaves of Araucaria heterophylla.

There are several studies that announce the inhibitory behavior of this sort of substance to strengthen the shield of metals, which is one of the positive benefits of green inhibitors. In the current investigation, Araucaria heterophylla studied as a green corrosion inhibitor to avert the mild steel during the acidic cleaning. The examination of this plant's ability to control corrosion at different concentrations in the acidic solution used certain expert measures.

Functional characterization of novel RbTI gene from ricebean and validation of its insecticidal properties in transgenic tobacco.

Plant protease inhibitors (PI's) inhibit the activity of gut proteases and thus provide resistance against insect attack. Previously we have published first report on cloning and characterization of a novel Bowman-Birk protease inhibitor gene (RbTI) from ricebean (Vigna umbellata). In this study, the RbTI gene was further characterized and validated as a potential candidate for transferring insect resistance in economically important crops.

Kissing Carotids: A Rare Anatomical Aberration with Clinical Significance.

Unlabelled: Kissing Carotids is a term given for an anatomical variation in which bilateral internal carotid arteries are medially placed in the retropharyngeal space and are juxtaposed to each other. Though this condition is asymptomatic it can lead to abrupt catastrophic bleeding during oral surgical procedures and tracheal intubation. This variation can be diagnosed with a contrast enhanced computed tomography and can alert the surgical team.

Efficient production of polyhydroxybutyrate using lignocellulosic biomass derived from oil palm trunks by the inhibitor-tolerant strain Burkholderia ambifaria E5-3.

Lignocellulosic biomass is a valuable, renewable substrate for the synthesis of polyhydroxybutyrate (PHB), an ecofriendly biopolymer. In this study, bacterial strain E5-3 was isolated from soil in Japan; it was identified as Burkholderia ambifaria strain E5-3 by 16 S rRNA gene sequencing. The strain showed optimal growth at 37 °C with an initial pH of 9.

Production of single cell oil by Lipomyces starkeyi from waste plant oil generated by the palm oil mill industry.

Only a few reports available about the assimilation of hydrophobic or oil-based feedstock as carbon sources by Lipomyces starkeyi. In this study, the ability of L. starkeyi to efficiently utilize free fatty acids (FFAs) and real biomass like palm acid oil (PAO) as well as crude palm kernel oil (CPKO) for growth and lipid production was investigated.

Effects of poly(3-hydroxybutyrate) [P(3HB)] coating on the bacterial communities of artificial structures.

The expanding urbanization of coastal areas has led to increased ocean sprawl, which has had both physical and chemical adverse effects on marine and coastal ecosystems. To maintain the health and functionality of these ecosystems, it is imperative to develop effective solutions. One such solution involves the use of biodegradable polymers as bioactive coatings to enhance the bioreceptivity of marine and coastal infrastructures.

Risk factors and etiology of early-onset neonatal sepsis in Northeastern part of India: Case-control study.

Background: Sepsis, the second most common cause of neonatal mortality, causes more than one million deaths annually. India has the highest incidence of clinical sepsis (17000/100000 live birth).

Objective: This study aimed to determine the risk factors and organisms of early-onset neonatal sepsis (EONS) in a tertiary care hospital in Northeast India.

Review of acute pancreatitis in children in India.

In the last two decades, the incidence of a cute pancreatitis (AP) in children has increased. Knowing different aspects of this condition like incidence, etiology, and severity is essential for the prevention and management of AP. There is a paucity of well-defined research in India on this topic.

Unusual Case Report of Headache in 10-Year-Old Female Child.

According to the literature, transverse sinus hypoplasia is not a normal variant and has a serious potential effect on cerebral blood flow. We are presenting a rare case of chronic headache due to severe hypoplasia of the left transverse and sigmoidal sinus. A 12-year-old female girl was admitted with a complaint of gradual progressive severe headache, throbbing in nature, confined to a bitemporal and frontal region in the last 4-5 months.

N-terminal truncation of PhaC and its effect on PHA production.

Background: Among the polyhydroxyalkanoate (PHA), poly[(R)-3-hydroxybutyrate-co-(R)-3-hydroxyhexanoate] [P(3HB-co-3HHx)] is reported to closely resemble polypropylene and low-density polyethylene. Studies have shown that PHA synthase (PhaC) from mangrove soil (PhaC) is an efficient PhaC for P(3HB-co-3HHx) production and N-termini of PhaCs influence its substrate specificity, dimerization, granule morphology, and molecular weights of PHA produced. This study aims to further improve PhaC through N-terminal truncation.

High Altitude Head and Neck Paragangliomas: A First Sub-Himalayan Experience.

Objectives: High-altitude natives have a high incidence of parangangliomas (PGL) of the head and neck, especially the carotid body tumor. The aim of this study is to describe the clinical presentation, pattern, altitude of residence, distribution, management, and follow-up of head and neck paragangliomas (HNPGL) in our sub-Himalayan population.

Study Design: Retrospective cohort study.

Assessment of awareness and knowledge regarding nuclear medicine and appropriate use of Nuclear medicine modalities, among medical students and faculty members in two academic medical institutes in North India: A Cross sectional Study.

Objectives: Despite significant progress in the field of nuclear medicine, basic nuclear medicine awareness and understanding among clinicians remains unsatisfactory, leading to under utilization of nuclear medicine modalities. To evaluate the awareness and knowledge regarding nuclear medicine and appropriate use of Nuclear medicine modalities, among medical students and faculty members.

Method: In this descriptive cross sectional study, a self timer limited objective questionnaire based on Google forms was distributed to the study population and scores obtained by the participants were analyzed.

Sustainable oil palm trunk fibre based activated carbon for the adsorption of methylene blue.

Activated carbon (AC) is becoming the limelight due to its widespread application as an adsorbent for wastewater treatment, gases, and catalysis. However, its high consumption and price have drawn more attention to the sustainable use of natural resources as precursor for AC production. This study focuses on synthesising AC from two types of oil palm trunk (OPT) fibres, a significant agricultural waste products produced by Malaysia's thriving palm oil industries.

Insights into biofilm development on polyhydroxyalkanoate biofilm carrier for anoxic azo dye decolourization of acid orange 7.

Polyhydroxyalkanoates (PHAs) are promising alternatives to non-degradable polymers in various applications. This study explored the use of biologically recovered PHA as a biofilm carrier in a moving bed biofilm reactor for acid orange 7 treatment. The PHA was comprised of 86 ± 1 mol% of 3-hydroxybutyrate and 14 ± 1 mol% of 3-hydroxyhexanoate and was melt-fused at 140 °C into pellets.

Review of inhalable nanoparticles for the pulmonary delivery of anti-tuberculosis drugs.

Tuberculosis is an airborne disease caused by the pathogen, , which predominantly affects the lungs. World Health Organization (WHO) has reported that about 85% of TB patients are cured with the existing 6-month antibiotic regimen. However, the lengthy oral administration of high-dose anti-TB drugs is associated with significant side effects and leads to drug resistance cases.

TiO loaded on glycidol functionalized poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) nanobiocomposite film for photocatalytic and antibacterial activities.

The rapid acceleration of industrialization and urbanization has exacerbated water pollution, which is primarily caused by the presence of highly toxic, non-biodegradable contaminants in industrial waste and effluents. In response to this urgent issue, a novel nanobiocomposite film with titanium dioxide (TiO) loaded onto a poly(3-hydroxybutyrate-co-18 mol% 3-hydroxyhexanoate) (18PHBH) matrix was developed to serve as an effective dual-function material with photocatalytic and antibacterial properties. Through Attenuated Total Reflectance-Fourier Transform Infrared (ATR-FTIR), Diffuse reflectance ultraviolet-visible (DRUV-Vis), Scanning Electron Microscope (SEM), and X-ray diffraction (XRD) analyses, the physicochemical properties of the TiO/Gly/18PHBH nanobiocomposite film were exhaustively characterized, revealing effective TiO loading and uniform distribution on the film's surface.