MoSe nanosheet/Si heterojunction photodetectors were fabricated by a mechanical exfoliation method, and their electrical and optical properties at different temperatures were investigated. It was found that the MoSe nanosheet/Si heterojunction device exhibited excellent rectification characteristics at room temperature, and the rectification ratio gradually decreased with the decrease of temperature. The temperature-dependent electrical properties of the MoSe/Si heterojunction device were actually caused by the inhomogeneity of the potential barrier.
View Article and Find Full Text PDFAluminum (Al) is a cost-effective alternative to noble metals for plasmonics, particularly in the ultraviolet (UV) and visible regions. However, in the near-infrared (NIR) region, its performance is hindered by interband transitions (IBTs) at around 825 nm, leading to increased optical losses and broad resonances. Surface lattice resonances (SLRs) offer a promising solution by enhancing the plasmonic quality factor (-factor) through coherent coupling of localized surface plasmon (LSP) modes with Rayleigh anomalies.
View Article and Find Full Text PDFAbnormal accumulation of TAR DNA-binding protein-43 (TDP-43) is a hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). Small interfering RNAs (siRNAs) targeting TDP-43 offer potential therapeutic strategies for these diseases. However, efficient and safe delivery of siRNAs to the central nervous system (CNS) remains a critical challenge.
View Article and Find Full Text PDFAvian influenza virus infections pose a potential pandemic threat. The currently licensed vaccines have inherent limitations, emphasizing the urgent need for improved influenza vaccines. Here, we developed a novel hemagglutinin (HA) virus-like particle (VLP) vaccine candidate through the baculovirus expression vector system (BEVS).
View Article and Find Full Text PDFBiochem Biophys Res Commun
August 2025
Malignant tumors present a major global health burden, as they generally have a poor prognosis, and the efficacy of available treatments is limited. Copine family members (CPNEs) play crucial roles in the regulation of tumor cell proliferation, metastasis, and therapeutic resistance, as well as in tumor diagnosis and prognostic risk stratification. CPNEs can facilitate tumor cell survival by regulating cell cycle progression and cell death.
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