Publications by authors named "Rui-Ling Lu"
Objectives: Systemic lupus erythematosus (SLE) has been associated with gut microbiota in some studies. There is no clear evidence that cytokines act as mediators.
Methods: We first assessed the differences in gut microbiota between SLE patients and healthy controls using 16S rDNA sequencing.
Background: The burden of interstitial lung disease (ILD)-associated heart failure (HF) poses a significant challenge to the prognosis of ILD patients. This study aimed to characterize the disease burden and analyse future trends of ILD-associated HF, offering valuable insights to inform targeted prevention and control strategies.
Methods: Data on the prevalence and years lived with disability (YLDs) of ILD-associated HF were retrieved from the Global Burden of Disease (GBD) database for the period 1990-2021.
Article Synopsis
- This study examines the connection between adult-onset asthma and ulcerative colitis (UC), finding that asthma increases the risk of UC.
- The research used extensive data from Genome-Wide Association Studies (GWAS) and involved a two-sample Mendelian Randomization analysis to explore this relationship.
- Interleukin-18 (IL-18) was identified as a potential mediator, but it only accounted for a small portion of the link between asthma and UC, prompting the need for further investigation into other contributing factors.
Article Synopsis
- Scurvy is caused by a deficiency of vitamin C, leading to general symptoms like weakness, malaise, and fatigue, which can make it easy to misdiagnose.
- Recent cases of scurvy in children are rare, and it’s even less common in young adults.
- A 25-year-old male, with no prior health issues, experienced severe pain and bruising in his legs due to a lack of outdoor activity and poor diet, ultimately being diagnosed with scurvy.