Effect of charcoal-based dentifrices on the surface integrity and gloss of lithium disilicate glass-ceramics.

Objectives: To evaluate the effects of commercially charcoal-based dentifrices on the surface roughness and gloss retention of glazed lithium disilicate glass-ceramics subjected to simulated toothbrushing.

Materials And Methods: Seventy-two glazed lithium disilicate specimens (IPS e.max CAD) were randomly assigned to three dentifrice groups (n = 24): two charcoal-based (Carvvo (CVV), Curaprox Black is White (CBW)) and one conventional (Colgate Total 12 (C12)), the control.

Potential of irrigants and medicaments in regenerative endodontics: insights from a systematic review on dentin growth factor release.

This study systematically reviews the literature on protocols used in regenerative endodontic procedures, focusing on the relationship between irrigants, intracanal medicaments, and the release of dentin-derived growth factors, which form one of the foundational pillars of regenerative endodontics. Systematic searches were conducted in PubMed, Web of Science, Scopus, Google Scholar, and gray literature for English studies (2015-2024). The included studies investigated growth factor release associated with irrigants or intracanal medicaments in human dentin.

Simple post-curing methods to optimize the depth of cure and physicochemical properties of 3D printed resin.

Objectives: This in vitro study evaluated the effect of different post-curing methods on the degree of conversion, mechanical properties, and color change of a 3D printing resin.

Methods: Specimens of a 3D printing resin were subjected to different post-curing processes: CONo post-curing; PCC-Post-curing in a violet light chamber; VA-Post-curing with VALO; HC-Post-curing in an oven; HP-Post-curing in an autoclave; PCC+HC-Post-curing in a violet light chamber associated with an oven; PCC+HP-Post-curing in a light chamber associated with an autoclave. The 3D printing accuracy, flexural strength, flexural modulus, Knoop microhardness and degree of depth conversion, surface hardness before and after immersion in solvent, gloss and roughness before and after brushing cycles, and color change after aging in UV light were evaluated.

From names to concepts: Unraveling bioactivity in restorative dental materials.

Background: The authors aimed to establish the scope and types of evidence concerning the bioactivity of materials used in restorative dentistry. The investigation adhered to the Preferred Reporting Items for Systematic reviews and Meta-Analyses Extension for Scoping Reviews and Joanna Briggs Institute methodologies for scoping reviews and was registered on the Open Science Framework platform.

Types Of Studies Reviewed: A systematic search was conducted across PubMed/MEDLINE, Embase, Scopus, and Web of Science databases through May 31, 2024, along with gray literature and manual searching of the list of references in the articles.

Preventing Oral Dual Biofilm Development with Innovative Bioactive Varnishes.

This study introduces innovative varnishes incorporating natural bioactive compounds to inhibit the formation of oral dual biofilms, a critical contributor to dental caries and other oral diseases. The purpose of this study was to evaluate the effectiveness of bioactive varnishes containing -farnesol, quercetin, and theobromine in inhibiting the formation of mixed and biofilms. Mixed biofilms of UA159 and SC5314 were grown in 96-well plates containing a specialized culture medium.

Bioactive Compounds Enhance the Biocompatibility and the Physical Properties of a Glass Ionomer Cement.

In order to characterize a novel restorative material, knowledge about the toxicological effect on human cells and the physical behavior of a glass ionomer cement (GIC) containing flavonoids was established. The flavonoids apigenin, naringenin, quercetin, and liquiritigenin were manually incorporated into a GIC. In the control group, no incorporation was performed.

Impact of COVID-19 on pediatric dental care in two epicenters: Italy and Brazil.

The study aimed to compare the adherence of Brazilian and Italian pediatric dentists to the biosafety measures and operative protocols recommended by the health authorities during COVID-19 pandemic and to classify the participants according to their risk of infection. An online questionnaire with 34 questions about sociodemographic and occupational data, dental practice organization, biological risk management, and clinical operative protocols was sent to Brazilian and Italian pediatric dentists using a convenience sampling strategy. Chi-square test and multivariate analysis (two-step cluster) were performed (α = 5%).

Exploring the role of flavonoids in caries-affected dentin adhesion: A comprehensive scoping review.

Objectives: The aim of this scoping review was to evaluate the available scientific evidence regarding the use of flavonoids in the treatment of caries-affected dentin focusing on bonding to dentin.

Methods: A comprehensive literature search was performed in five databases from March 2022 and updated in April 2023: PubMed, EMBASE, Scopus, Web of Science, and Scielo. Additionally, the references of included studies were manually searched.

Teaching pulpectomy in paediatric dentistry: A national cross-sectional survey of dental schools in Brazil.

Background: Pulpectomy is used to treat primary teeth with irreversibly inflamed or necrotic pulp tissue. There is, however, a lack of consensus on clinical protocols for teaching pulpectomy at dental schools.

Aim: To determine what faculty members at Brazilian dental schools are teaching about pulpectomy in primary teeth.

Mechanical stress distribution over the palate by different pacifiers assessed by finite element analysis and clinical data.

The mechanical behavior of each type of pacifier on rigid structures and their various impacts on orofacial growth have yet to be discovered. The study aimed to evaluate the stress distribution over a child's palate by three types of pacifiers using finite element analysis and clinical and laboratory data. Modulus of elasticity was obtained from 30 specimens comprising 10 of each conventional (A), orthodontic (B), and breast-shaped (C) pacifiers.

Effect of Biosilicate Addition on Physical-Mechanical and Biological Properties of Dental Glass Ionomer Cements.

This study investigated the influence of incorporating Biosilicate on the physico-mechanical and biological properties of glass ionomer cement (GIC). This bioactive glass ceramic (23.75% NaO, 23.

The Self-assembling peptide P-4 influences viability and osteogenic differentiation of stem cells of the apical papilla (SCAP).

Objective: To analyze the effect of P-4 self-assembly peptide on cell viability and osteogenic capacity of SCAPs through mineral deposition and gene expression of osteogenic markers.

Methods: SCAPs were seeded in contact with P-4 (10 µg/ml, 100 µg/ml and 1 mg/ml) solution. Cell viability was evaluated using a colorimetric assay MTT: 3-(4,5-dimethyl-thiazolyl-2)-2,5- diphenyltetrazolium bromide) in an experimental time of 24, 48 and 72 h (n = 7).

TiO2 nanotube-containing glass ionomer cements display reduced aluminum release rates.

Titanium dioxide nanotubes (TiO2-nts) were incorporated into a glass ionomer cement (GIC) with improved mechanical properties and antibacterial activity. The aims of the present in vitro study were to define the elemental characterization, aluminum (Al) release rate, and initial working time for GIC reinforced with TiO2-nts, in an experimental caries model. TiO2-nts were incorporated into GIC powder components at 5% by weight, and compared with unblended GIC.

Self-assembly peptide P-4 induces mineralization and cell-migration of odontoblast-like cells.

Objectives: Self-assembling peptide P-4 is amphiphilic and pH-triggered, effective on repairing early enamel carious lesions and dentin remineralization. However, P-4 effects on dentin biomineralization and repair ability remain unexplored. Thus, cytocompatibility and effectiveness of P-4 on inducing mineralization and migration of odontoblast-like cells (MDPC-23) were investigated.

CHX Stabilizes the Resin/demineralized Dentin Interface.

The aim of this study was to evaluate the effect of 2% chlorhexidine digluconate (CHX) on microtensile bond strength (µTBS) between an adhesive system and under 3 dentin conditions. For that, this study evaluated the adhesive interface at initial, after 6 months and 1 year of storage. Forty-eight human third molars were prepared and randomly divided into 3 groups, according to dentin substrates: sound dentin (Sd), caries-infected dentin (Ci) and caries-affected dentin (Ca).

Correction: Trans,trans-farnesol, an antimicrobial natural compound, improves glass ionomer cement properties.

[This corrects the article DOI: 10.1371/journal.pone.

Titanium dioxide nanotubes added to glass ionomer cements affect S. mutans viability and mechanisms of virulence.

This in vitro study evaluated the impact of TiO2 nanotubes (n-TiO2) incorporated into glass ionomer cement (GIC) on Streptococcus mutans (S. mutans) characteristics at cellular and molecular levels. n-TiO2, synthesized by the alkaline method (20 nm in size), was added to Ketac Molar EasyMix® at 0%, 3%, 5%, and 7% by weight.

Analysis of enamel/restoration interface submitted cariogenic challenge and fluoride release.

The treatment of high-risk patients still is a challenge. The understanding and development non-invasive, non-destructive, and non-ionizing techniques, can help to guide the treatment and the diagnosis of primary and recurrent caries. The present study evaluated the behavior of enamel/restoration interface after a cariogenic challenge by Fourier domain optical coherence tomography (FD-OCT), scanning electron microscopy (SEM) examination, and the fluoride release of the different restorative materials.

Consensus on glass-ionomer cement thresholds for restorative indications.

Objective: The aim of this paper is to present the results of a consensus meeting on the threshold property requirements for the clinical use of conventional glass-ionomer cements (GICs) for restorative indications.

Methods: Twenty-one experts on GICs evaluated the results of tests on mechanical and optical properties of 18 different brands of restorative GICs: Bioglass R [B], Chemfil Rock [CR], Equia Forte [EF], Gold Label 2 [GL2], Gold Label 9 [GL9], Glass Ionomer Cement II [GI], Ionglass [IG], Ion Z [IZ], Ionomaster [IM], Ionofil Plus [IP], Ionostar Plus [IS], Ketac Molar Easymix [KM], Magic Glass [MG], Maxxion R [MA], Riva Self Cure [R], Vidrion R [V], Vitro Fil [VF] and Vitro Molar [VM]. All experiments were carried out by a team of researchers from Brazil and England following strict protocols, under the same laboratory conditions throughout, and maintaining data integrity.

Impact of biomineralization on resin/biomineralized dentin bond longevity in a minimally invasive approach: An "in vitro" 18-month follow-up.

Objectives: To determine the impact of treating caries-affected dentin (CAD) with: 0.2% sodium fluoride (NaF), casein phosphopeptide-amorphous calcium phosphate (CPP-ACP/MI Paste™) or peptide P-4 (Curodont™ Repair) on the longevity of resin/CAD interface at storage times of 24 -h, 6- and 18-month.

Methods: 255 caries-free third molars were used, and CAD was produced by a biological method.

Fluoride release and remineralizing potential of varnishes in early caries lesions in primary teeth.

This study evaluated the fluoride (F) release and remineralizing potential of varnishes containing sodium fluoride (5% NaF), 5% NaF with CPP-ACP and 5% NaF with TCP in early caries lesions in primary teeth. To determine the F release at 1, 4, 6, 24, 72, and 168 hr, strips were covered with the varnishes and immersed in purified water (n = 7). The varnishes and purified water (negative control) were applied on enamel blocks with early caries lesions (n = 16).

Physical-Mechanical Properties of Bulk Fill Composites Submitted to Biodegradation by Streptococcus mutans.

The aim of this study was to evaluate the Streptococcus mutans biofilm influence on the roughness (Ra), gloss (GU), surface hardness (KHN) and flexural strength (FS) of high viscosity bulk fill composites. Filtek Bulk Fill (FBF), Tetric N Ceram Bulk Fill (TNC), X-tra fil Bulk Fill (XF) and Filtek Z350 (FZ) were used. Ten discs of each composite were prepared for Ra, KHN and GU and 20 bars for the FS.

Effect of Intracanal Medicaments and Irrigants on the Release of Transforming Growth Factor Beta 1 and Vascular Endothelial Growth Factor from Cervical Root Dentin.

Introduction: This study aimed to evaluate (1) the effect of irrigating solutions and intracanal medicaments on the release of transforming growth factor beta 1 (TGF-β1) and vascular endothelial growth factor (VEGF) from cervical root dentin and (2) the effect of associating triple antibiotic paste (TAP) and calcium hydroxide paste (CH) with 2% chlorhexidine (CHX) on TGF-β1 release.

Methods: First, 119 specimens from roots (cervical thirds) were obtained and were distributed into 5 groups: 2% CHX, 2.5% sodium hypochlorite, TAP, CH, and 10% EDTA by each growth factor (TGF-β1 [n = 8] and VEGF [n = 8]).