A comprehensive review on selenium and blood pressure: Recent advances and research perspectives.

Background: Globally, approximately 31.1 % of adults are affected by hypertension(HTN), and there is currently no effective treatment for this condition. Selenium (Se), an essential trace element in the human body, has been shown to play a role in various biological processes, including anti-inflammation, antioxidative stress, anti-ferroptosis, and regulation of immune response.

Fraxinellone protects against cardiac injury and decreases ventricular fibrillation susceptibility during myocardial ischemia-reperfusion.

Background: Acute myocardial ischemia/reperfusion injury (MIRI) with complicated mechanisms contributes to a high risk of ventricular arrhythmia, high lethality, and even sudden death. In vitro, Fraxinellone (FRA) exhibits an array of biologic activities and may possess cardioprotective effects. However, no relevant studies have examined FRA's protective potential against MIRI and related ventricular arrhythmias.