Publications by authors named "Pushpendra Kumar Shukla"

Article Synopsis
  • Peyronie's disease (PD) leads to fibrous changes in the penis, requiring surgical intervention like corporoplasty with grafting to correct severe curvature; lingual mucosal graft (LMG) is being researched as a promising treatment option.
  • A study involving 19 patients undergoing corporoplasty with LMG showed that 89% achieved significant curvature correction (<10°), with 63% experiencing an increase in penile length, while patient satisfaction rates were notably high.
  • The results indicated LMG is effective and safe with minimal complications, but further multicenter studies are needed for confirmation and longer-term insights.
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Gloriosa superba L. has economic significance due to colchicine, a bioactive compound used for gout. In present study metabolic and molecular variability in natural population of species was analyzed and correlated with edaphic and climatic factors.

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Ethnopharmacological Relevance: Gloriosa superba L. (Colchicaceae) is used in the treatment of gout and rheumatism as a traditional medicine dates back to 1810. It has also been used as ethnobotanical and folklore medicine to induce abortion/vaginal poison.

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The variation in alkaloid metabolites (colchicine and gloriosine) was found significant in the nine germplasms of (L.), collected from Central India. The maximum content of colchicine and gloriosine was in NBG-15 (Chitrakoot, M.

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Background: is a well-known industrially important medicinal plant, for its high forskolin content.

Objective: A simple, selective, and sensitive high-performance thin layer chromatography (HPTLC) method was developed and validated for simultaneous quantification of forskolin and iso-forskolin in germplasm collected from the Eastern Ghats, India.

Materials And Methods: Chromatographic separation of the targeted marker(s) was obtained on precoated silica plates using toluene: ethyl acetate: methanol (90:30:0.

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Background: L. (Colchicaceae) is used as adjuvant therapy in gout for its potential antimitotic activity due to high colchicine(s) alkaloids.

Objective: This study aimed to develop an easy, cheap, precise, and accurate high-performance thin-layer chromatographic (HPTLC) validated method for simultaneous quantification of bioactive alkaloids (colchicine and gloriosine) in L.

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Content: Different Leucas species are well known as "Dronpushpi," a well-known herb of Ayurveda, used in the treatment of various ailments.

Objective: Evaluation of four industrially important Leucas species for their in vitro antidiabetic potential and radical scavenging effect along with high-performance liquid chromatographic quantification of the bioactive triterpenes.

Materials And Methods: The quantification of triterpenes was carried out on C-18 column with acetonitrile and water (90:10) as the solvent system at a detection wavelength of 210 nm.

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