An AIE-activated fluorescent sensor for one-step concurrent detection and bioimaging of perfluorooctanoic acid and perfluorooctane sulfonate in vitro and in vivo.

Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) have emerged as global concerns due to their environmental persistence and associated toxicity. Therefore, accurate detection of PFOA/PFOS in water samples and biological systems is of great importance. In this study, we have designed and synthesized a novel fluorescent sensor ES based on tetraphenyl derivatives for one-step concurrent detection of PFOA and PFOS.