Spiking frequency adaptability and multi-weight synergy in artificial neuronal modules bifunctional NbO memristors.

To address the limitations of current artificial neurons in neuromorphic hardware implementation, NbO-based bifunctional memristors are fabricated to construct oscillatory units and advanced neuronal modules. NbObased memristors operate as either threshold-switching memristors (TSMs) or dynamic memristors (DyMs), depending on whether electroforming is applied. TSMs are employed to build oscillatory units and further reconfigured into a weighted multi-terminal neuronal module, enabling real-time spatiotemporal summation of input spikes based on the leaky integrate-and-fire model.

Achieving neuronal dynamics with spike encoding and spatial-temporal summation in vanadium-based threshold switching memristor for asynchronous signal integration.

Artificial neuronal devices that emulate the dynamics of biological neurons are pivotal for advancing brain emulation and developing bio-inspired electronic systems. This paper presents the design and demonstration of an artificial neuron circuit based on a Pt/V/AlO/Pt threshold switching memristor (TSM) integrated with an external resistor. By applying voltage pulses, we successfully exhibit the leaky integrate-and-fire (LIF) behavior, as well as both spatial and spatiotemporal summation capabilities, achieving the asynchronous signal integration.

Hypotension prediction index for prevention of intraoperative hypotension in patients undergoing general anesthesia: a randomized controlled trial.

Background: Intraoperative hypotension is a common side effect of general anesthesia. Here we examined whether the Hypotension Prediction Index (HPI), a novel warning system, reduces the severity and duration of intraoperative hypotension during general anesthesia.

Methods: This randomized controlled trial was conducted in a tertiary referral hospital.

Apolipoprotein E4 allele is genetically associated with risk of the short- and medium-term postoperative cognitive dysfunction: A meta-analysis and trial sequential analysis.

The aim of systematic review and meta-analysis was to investigate whether APOE4 was associated with postoperative neurologic dysfunction occurrence in short- or medium-term among surgical patients and to study the potential genetic association among these two entities. We searched electronic databases for reserch studies to evaluate the association of APOE4 with postoperative delirium (POD) or short- and medium term postoperative cognitive dysfunction (POCD). Twenty-two trials (16 prospective and six retrospective) with 6734 patients were included.

Efficacy and safety of remifentanil for endoscopic ultrasound-guided tissue acquisition: a single center retrospective study.

Background: Remifentanil is a rapid onset and rapid recovery opioid. The combination of remifentanil and propofol for deep sedation decreases the incidents of movement, cough, and hiccup. We evaluated the efficacy and safety of remifentanil during endoscopic ultrasound-guided tissue acquisition.

Synthesis, Characterization, and Pharmacodynamics Study of Enrofloxacin Mesylate.

Introduction: Enrofloxacin is used in the treatment of a wide variety of bacterial infections in mammals. However, its poor solubility limits the clinical use.

Methods: In order to improve the solubility of enrofloxacin, the enrofloxacin mesylate (EM) were obtained by a chemical synthesis method.

Target-controlled propofol infusion with or without bispectral index monitoring of sedation during advanced gastrointestinal endoscopy.

Background And Aim: Target-controlled infusion (TCI) uses averaged pharmacokinetic datasets derived from population samples to automatically control the infusion rate. Bispectral index (BIS) technology non-invasively measures levels of consciousness during surgical procedures. We compared the efficacy and safety of propofol TCI with or without BIS monitoring for sedation during advanced gastrointestinal endoscopy.

A survey of one-lung ventilation device in lung resection surgeries in Taiwan-A population-based nationwide cohort study.

Background: Double-lumen endotracheal tubes and bronchial blockers are the two lung separation devices most commonly used for lung resection. The preference and outcomes of choosing different lung separation devices have not been discussed in the literature.

Methods: This study was conducted using the data of 2 million patients randomly chosen from the National Health Insurance Research Database between 2011 and 2016.

Platelet activation in diabetic mice models: the role of vascular endothelial cell-derived protein disulfide isomerase-mediated GP IIb/IIIa receptor activation.

GP IIb/IIIa receptor activation plays an important role in thrombosis. The mechanism of early activation of GP IIb/IIIa receptors in diabetic conditions remains unknown. The purpose of this study was to investigate the release of Endothelial microparticle (EMP)-associated protein disulfide isomerase (PDI) after endothelial cell injury induced in diabetes and the changes in platelet activation.

Manual acupuncture relieves bile acid-induced itch in mice: the role of microglia and TNF-α.

Pruritus, or itch, is a frequent complaint amongst patients with cholestatic hepatobiliary disease and is difficult to manage, with many patients refractory to currently available antipruritic treatments. In this study, we examined whether manual acupuncture (MA) at particular acupoints represses deoxycholic acid (DCA)-induced scratching behavior and microglial activation and compared these effects with those induced by another pruritogen, 5'-guanidinonaltrindole (GNTI, a kappa opioid receptor antagonist). MA at Hegu (LI4) and Quchi (LI11) acupoints significantly attenuated DCA- and GNTI-induced scratching, whereas no such effects were observed at the bilateral Zusanli acupoints (ST36).

Decreased Parasympathetic Activity of Heart Rate Variability During Anticipation of Night Duty in Anesthesiology Residents.

Background: In residency programs, it is well known that autonomic regulation is influenced by night duty due to workload stress and sleep deprivation. A less investigated question is the impact on the autonomic nervous system of residents before or when anticipating a night duty shift. In this study, heart rate variability (HRV) was evaluated as a measure of autonomic nervous system regulation.

Pretreatment serum lactate level as a prognostic biomarker in patients undergoing supratentorial primary brain tumor resection.

Introduction: Malignant primary brain tumors are one of the most aggressive cancers. Pretreatment serum nonneuronal biomarkers closely associated with postoperative outcomes are of high clinical relevance. The present study aimed to identify potential pretreatment serum biomarkers that may influence oncological outcomes in patients with primary brain tumors.

Long-term outcomes of totally implantable venous access devices.

Purpose: Identifying risk factors for premature totally implantable venous access device (TIVAD) catheter removal is crucial; however, because of the diversity of study methodologies, there is no consensus on such factors. The objective of the present study was to identify such risk factors by applying a cohort design study with a long-term follow-up period.

Methods: For this cohort study, we selected cancer patients who had newly implanted TIVADs between July 2008 and December 2008.

[The Snapshot Imaging Spectrometer with Image Replication Based on Wallaston Prism].

In this paper, a kind of snapshot imaging spectrometer is designed by using image replication based on Wollaston prism. The system includes telephoto lens, collimator lens, Wollaston prism, the imaging lens and compensation filters. With this optical system, we can obtain two-dimensional information at different wavelengths of the same target through one time exposure.

[Analysis of Influence of Pushroom Erros on The Data Reconstruction of Computational Imaging Spectrometer].

The technology of computational spectral imaging changes the traditional imaging modalities by introducing a coded aperture in the optical path to achieve transformation of the targets spectral imformation, then we can get the spectral data cube by reverse transform. This paper introduces the principle of a push-broom imaging coded aperture computational spectral imager. In practical applications, the matching error between the push speed and the frame rate can affect the accuracy of the spectral data reconstruction.

[Effect evaluation of optical magnification errors for coded aperture spectrometer].

In the present paper, we simulated the system optical magnification error's influence on the quality of reconstructed image, analyzed the variant of the coded aperture with different optical magnification, then proposed an accurate curve of image quality and optical magnification in 128 x 128 code template, which provide important references for the design and development of push-broom coded aperture spectrometer.

The effects of different epidural analgesia formulas on labor and mode of delivery in nulliparous women.

Objectives: Patient-controlled epidural analgesia (PCEA) and continuous epidural infusion (CEI) are popular and effective methods for pain relief during labor; however, there are concerns about increasing rates of cesarean section (C/S) and instrumental delivery. This prospective study investigated the effect of PCEA and CEI with different formulas on labor and the mode of delivery in nulliparous women.

Materials And Methods: A total of 480 nulliparous women were randomized into four groups, with 120 in each.

Relationship of abdominal circumference and trunk length with spinal anesthesia level in the term parturient.

Background: We hypothesized that body shape metrics influence the anatomy of spinal canal and intraabdominal pressure in three dimensions. We explored the effects of abdominal circumference, trunk length, and their combination on the level of spinal anesthesia in the term parturient in this study.

Methods: Thirty term parturients, ASA class I-II, from 20 to 41 years of age, scheduled for cesarean section were enrolled in this observational study.

[Interference hyperspectral data compression based on spectral classification and local DPCM].

In order to get a high compression ratio, according to the spatial dimension correlation and the interference spectral dimension correlation of interference hyperspectral image data, the present article provides a new compression algorithm that combines spectral classification with local DPCM. This algorithm requires spectral classification for the whole interference hyperspectral image to get a classification number matrix corresponding to the two-dimensional space and a spectral classification library corresponding to the interference spectra first, then local DPCM is performed for the spectral classification library to get a further compression. As the first step of the compression, the spectral classification is very important to the compression effect.

Patient -controlled epidural ropivacaine as a post-Cesarean analgesia: a comparison with epidural morphine.

Objective: Conventional, intermittent, epidural morphine is widely applied as a post-Cesarean delivery analgesia. We compared the analgesic efficacy, motor weakness, and side effects of administering a patient-controlled epidural analgesia (PCEA) of pure ropivacaine versus the intermittent administration of epidural morphine after Cesarean delivery.

Materials And Methods: This randomized, double-blind study included 120 full-term parturients who underwent elective Cesarean delivery and received either PCEA with pure ropivacaine or an intermittent bolus epidural of 2 mg/10 mL morphine in normal saline twice per day.

Action potential bursts in central snail neurons elicited by procaine: roles of ionic currents.

The role of ionic currents on procaine-elicited action potential bursts was studied in an identifiable RP1 neuron of the African snail, Achatina fulica Ferussac, using the two-electrode voltage clamp method. The RP1 neuron generated spontaneous action potentials and bath application of procaine at 10 mM reversibly elicited action potential bursts in a concentration-dependent manner. Voltage clamp studies revealed that procaine at 10 mM decreased [1] the Ca2+ current, [2] the Na+ current, [3] the delayed rectifying K+ current I(KD), and [4] the fast-inactivating K+ current (I(A)).