Case: A 12-year-old girl with neurofibromatosis type 1 presented with progressive thoracic scoliosis and neurological deficit. Imaging revealed a dystrophic curve, dorsal syrinx, and tethering of the cord by a plexiform neurofibroma arising from the T7 dorsal ramus. She underwent staged surgery: detethering through T6-T8 laminectomy, followed by posterior spinal deformity correction with Schwab type 2 osteotomies and instrumentation.
View Article and Find Full Text PDFJ Clin Orthop Trauma
November 2025
Severe rigid scoliosis (>90° Cobb angle; <30 % flexibility) presents major challenges in deformity correction and pulmonary preservation. This narrative review outlines current surgical strategies, with a focus on anterior spinal release and its biomechanical and respiratory implications. Disc-rib-head excision improves axial rotation and sagittal alignment, reducing the need for extensive posterior osteotomies and high implant density.
View Article and Find Full Text PDFIntroduction: The overall incidence of vertebral artery (VA) variations is 2-3%, but among patients with congenital anomalies at the cranio-vertebral junction, it is 20%. Knowing these anomalies is important, if failed to recognize can lead to VA injury during surgery and subsequent cerebrovascular accidents.
Case Report: A 14-year-old boy presenting with progressive weakness of bilateral upper limb and lower limb was diagnosed as case of supra-axial cervical myelopathy due to congenital atlantoaxial subluxation with fenestration of VA and high-riding VA.
Introduction: Osteoarticular TB contributes to roughly 10% of the cases of extrapulmonary TB. The incidence of osteoarticular tuberculosis is one of the lowest in extrapulmonary tuberculosis, probably only next to cutaneous tuberculosis in non-HIV patients. Considering the low incidence of primary osteoarticular tuberculosis without pulmonary tuberculosis, we hypothesise that there is an element of tissue-specific immunity against tuberculosis in the body, which appears to be very high in bone and joints.
View Article and Find Full Text PDFStudy Design: Retrospective Comparative Study.
Objective: A comparative analysis was aimed at evaluating the clinical and radiological outcomes of cases managed with versus without ACR.
Summary Of Background Data: Management of spinal tuberculosis (STB) is accomplished with or without anterior column reconstruction (ACR).
Aims: In the absence of neurological deficits, the decision for surgery in spinal tuberculosis (STB) depends on the individual experiences of the surgeons, which may differ widely. There is currently no universal consensus on an objective definition of instability in STB. The Tuberculosis Spine Instability Score (TSIS) was developed to discriminate between the stable and unstable spine in STB.
View Article and Find Full Text PDFStudy Design: Network meta-analysis.
Objectives: To determine lowest instrumented vertebra (LIV) in Lenke 5 & 6 Adolescent Idiopathic Scoliosis (AIS) patients.
Methods: An extensive literature search was carried out aimed at identifying articles reporting outcomes in Lenke 5 and 6 AIS patients based on LIV selection.
Study Design: Prospective Observational Study.
Objective: The current study aims to explore the correlation of MRI and DTI parameters in acute thoracic spinal cord injuries for prediction of neurological outcomes.
Setting: University level tertiary care hospital of Northern India.
Background: Cervical spondylotic myelopathy (CSM) is a common cause of progressive neurological decline in elderly patients, often necessitating surgical decompression. Anterior cervical discectomy and fusion (ACDF) and anterior cervical corpectomy and fusion (ACCF) are commonly used procedures. However, there is no consensus on the superior approach, particularly in cases involving 2-level CSM.
View Article and Find Full Text PDFObjective: With numerous studies reporting on the clinical efficacy of ozone therapy, there has been a growing interest in its use for disc herniation in lumbar disc disease. The aim of this meta-analysis is to explore the results of the prospective studies using ozone for the treatment of lumbar disc disease.
Methods: Online electronic databases of PubMed, Embase and Scopus were searched using relevant keywords.
Spine (Phila Pa 1976)
June 2025
Study Design: Systematic review and meta-analysis.
Objective: To assess the safety and efficacy of staged versus same-day spinal fusion surgeries in adult spinal deformity (ASD).
Background: ASD surgeries are associated with high complication rates, ranging from 10% to 40%.
J Clin Orthop Trauma
November 2024
Orthopedic surgery and traumatology necessitate cost-effective approaches that can be replicated across multiple venues. Finite Element (FE) simulation models have evolved as a solution, allowing for consistent investigations into biomechanical systems. Finite Element Analysis (FEA), which began in the 1950s aviation industry, has since expanded into orthopedics.
View Article and Find Full Text PDFCase: A 47-year-old man presented with neck pain, restricted neck movements, along with involvement of facial and hypoglossal nerve. On the basis of clinico-radiological correlation, the patient was diagnosed with craniovertebral junction tuberculosis and was started on antitubercular therapy (ATT). Failing the conservative trial, the patient was operated and occipitocervical fusion was done with bone grafting.
View Article and Find Full Text PDFBackground: Diagnosis and management of developmental dysplasia of hip (DDH) in underdeveloped regions is frequently delayed, potentially impacting final outcomes. This prospective study was conducted with the aim of answering the question, "Do children <3 years at index surgery for DDH have better outcome at 5-year follow-up in comparison to children >3 years at index surgery?"
Methods: Between 2016 and 2021, all walking-age children with DDH were prospectively enrolled in the study. The study cohort was divided into 2groups: Group 1 ⩽3 years of age, and Group 2 included children >3 years old.
Study Design: Prospective observational cohort study.
Objective: To analyze the effect of decompression surgery on gait characteristics in patients with stenosis. Also, to test the hypothesis that patient-reported functional outcomes and gait parameters (spatiotemporal, kinetic, and kinematic measures) will improve postoperatively and achieve normal values when compared with matched healthy controls.
Study Design: Prospective Comparative Study.
Objectives: This study aims to study the outcome of thoracolumbar burst fractures by comparison of 3 different posterior constructs groups of patients treated by the posterior approach.
Setting: University level Tertiary care Centre of Northern India.
When addressing bone defects resulting from trauma, infection, or tumors, the use of allogenic bone is often necessary. While autografts are considered the standard, they have limitations and can lead to donor site morbidity. Consequently, there has been exploration into the feasibility of utilizing allogenic bone and bone graft replacements.
View Article and Find Full Text PDFBackground: The distribution of spinal tuberculosis (STB) differs due to variations in lifestyles, socio-economic conditions, geographical locations, available medical services, and other factors. In the literature, very few studies have been done on demographic profile and morphological distribution of tuberculosis (TB) spine. We conducted this study to identify the disease distribution and various parameters affecting the disease in our area which caters to populations from both plains and hills.
View Article and Find Full Text PDFBackground: Traumatic cervical spine injury is common among spinal cord injury which requires an intensive, multidisciplinary approach which can affect the immediate postoperative hospital survival rate. By identifying the risk factors leading to early mortality in cervical spine trauma patients, the prognosis of patients with TCSCI can be better predicted.
Objective: The study aims to analyze the variables influencing in-hospital mortality in cervical spine trauma patients treated at a Level I trauma Center.
The present work describes the development of TiO/SeO nanostructure as a potential candidate for visible light photocatalysis as well as selective fluorophore for the sensing of picric acid. The obtained nanostructure consists of uniform globular nanoparticles having approximate size of 170 nm and possess an optical band gap of 2.33 eV with absorption maxima at 473 nm.
View Article and Find Full Text PDFPurpose Of Study: To compare the outcomes of minimally invasive and open techniques in the surgical management of dorsolumbar and lumbar spinal tuberculosis (STB).
Methods: Skeletally mature patients with active STB involving thoracolumbar and lumbar region confirmed by radiology (X-ray, MRI) and histopathological examination were included. Healed and mechanically stable STB, patients having severe hepatic and renal impairment, coexisting spinal conditions such as ankylosing spondylitis and rheumatoid arthritis, and patients unwilling to participate were excluded from the study.