Publications by authors named "P B Janakiraman"

Introduction: The clivus is an uncommon site for fungal infections and is typically associated with tumors or metastases. Invasive fungal sinusitis extending to the skull base is exceptionally rare and often mimics clival malignancies such as chordomas or metastases. This overlap in clinical and radiological features can lead to diagnostic delays.

View Article and Find Full Text PDF
Article Synopsis
  • N6-methyladenosine (m6A) is a crucial regulator in RNA functions and is linked to cancer, particularly head and neck squamous cell carcinoma (HNSCC), which has a low survival rate.
  • Research indicates that m6A RNA methylation is elevated in HNSCC and affects various cancer-related processes like growth, cell death, and metastasis.
  • The study suggests that m6A modifications can serve as potential biomarkers for diagnosing and predicting outcomes in HNSCC and aims to provide a thorough review of m6A's role in cancer mechanisms.
View Article and Find Full Text PDF

Introduction: Geriatric hip fractures are a major cause of concern globally and often a frequent reason for morbidity and mortality. Postoperative delirium (POD) is a frequent but often under-diagnosed complication, especially after a major hip surgery. Some of the factors that have been associated with POD are diabetes, high American Society of Anesthesiologists (ASA) grading, electrolyte imbalance, and blood pressure fluctuations.

View Article and Find Full Text PDF

Purpose: To compare the clinical performance of the TECNIS Synergy multifocal (model ZFR00V) intraocular lens (IOL) with that of the AcrySof PanOptix Trifocal (model TFNT00) IOL in patients undergoing bilateral cataract surgery.

Setting: Multicenter clinical setting.

Design: Prospective randomized comparative study.

View Article and Find Full Text PDF

Background: Space occupying lesions (SOLs) of central nervous system (CNS) constitutes important cause of neurological morbidity and mortality. Squash cytology is technically a simple and rapid intraoperative diagnostic tool. Radiology is supportive of histopathological diagnosis.

View Article and Find Full Text PDF