Existing Data Sources in Clinical Epidemiology: The Danish Prehospital Medical Record System.

Background: The Danish Prehospital Medical Record (DPMR) represents a pioneering nationwide electronic prehospital medical record system. While routinely collected data from the DPMR are increasingly used for research, a comprehensive description of its system and content is needed.

Objective: To provide an overview of the DPMR as a tool for research, including its structure, variables, and current volume of records.

Prehospital Triage of Pediatric Emergencies Treated by Helicopter Emergency Medical Services: A Population-Based Cohort Study.

Objective: Helicopter emergency medical services (HEMS) play a crucial role in emergency medical services across many countries. Although some patients are discharged at the scene, most are transported to tertiary or local hospital emergency departments (EDs), with critically ill pediatric patients usually triaged to tertiary EDs. We evaluated whether critically ill pediatric patients treated by HEMS were primarily triaged to the highest level of care by comparing mortality between those admitted to tertiary versus local EDs.

Injury Severity Scoring in the Resuscitation Room-Is Preliminary Injury Severity Score Accurate?

Background: The Injury Severity Score (ISS) is a commonly used trauma assessment tool. An accurately calculated ISS is fundamental when used for the classification of the injury severity of trauma patients and subsequent evaluation of a trauma center's performance. This study aimed to analyze the accuracy of a preliminary ISS of trauma patients in the resuscitation room.

Video Versus Face-To-Face Preoperative Anaesthetic Assessment: The VIDFACE Trial-A Statistical Analysis Plan.

Background: The video versus face-to-face preoperative anaesthetic assessment (VIDFACE) trial is a randomised, multicentre, two-arm, superiority, assessor- and data analyst blinded clinical trial. The routine use of preoperative assessments is accepted as the gold standard for elective surgery, reducing both morbidity and mortality. In recent years, video-based assessments have been investigated with a focus on patient satisfaction and enhancing efficacy.

Analgesic Effect of Cocaine and Lidocaine/Xylometazoline in Healthy Volunteers Undergoing Awake Nasal Intubation: A Randomized Controlled Crossover Trial.

Background: Several drugs may be used to minimize pain during nasal intubation in awake patients. We hypothesized that the analgesic effect of cocaine would be at least as good (non-inferior) as that of lidocaine with xylometazoline rated as maximum pain felt during awake nasal intubation of healthy volunteers.

Methods: We conducted an outcome assessor blinded, randomized, triple crossover, non-inferiority study following approval from the local research ethics committee and the national medicine agency.

Hypoxemia in trauma patients receiving two different oxygen strategies: a TRAUMOX2 substudy.

Background: The randomized controlled trial, TRAUMOX2, compared early restrictive vs. liberal oxygen strategies for trauma patients. The objective of this substudy was to quantify the occurrence and duration of hypoxemic episodes during the trial's eight-hour intervention.

Cocaine to prevent bleeding during nasotracheal intubation: A systematic review.

Background: Nasotracheal intubation is associated with a risk of epistaxis. Decongestion of the nasal mucosa reduces the risk of epistaxis, and different vasoconstrictors may be used. Cocaine has both decongestive and analgesic properties, but it also has side effects.

Oxidative stress in trauma patients receiving a restrictive or liberal oxygen strategy - A sub-study of the TRAUMOX2 trial.

Introduction: A liberal supplemental oxygen approach is recommended for all severely injured trauma patients despite limited evidence. Liberal oxygen administration may cause oxidative stress. The aim of this study was to investigate the effect of an early restrictive oxygen strategy versus a liberal oxygen strategy in adult trauma patients on biomarkers of oxidative stress within 48 h of hospital admission.

Early Restrictive vs Liberal Oxygen for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial.

Importance: Early administration of supplemental oxygen for all severely injured trauma patients is recommended, but liberal oxygen treatment has been associated with increased risk of death and respiratory complications.

Objective: To determine whether an early 8-hour restrictive oxygen strategy compared with a liberal oxygen strategy in adult trauma patients would reduce death and/or major respiratory complications.

Design, Setting, And Participants: This randomized controlled trial enrolled adult trauma patients transferred directly to hospitals, triggering a full trauma team activation with an anticipated hospital stay of a minimum of 24 hours from December 7, 2021, to September 12, 2023.

The Danish National Hospital Medication Register: A Resource for Pharmacoepidemiology.

Background: The Danish National Hospital Medication Register (DHMR), one of the first nationwide in-hospital medication registries in the world, contains detailed information on medication administration and dispensing.

Objective: To provide an overview of the information recorded in the DHMR and to highlight its strengths and limitations as a pharmacoepidemiological research tool.

Methods: We reviewed the registry´s geographic and clinical specialty coverage and medications recorded according to the main groups of the Anatomical Therapeutic Chemical classification system.

Interhospital transfers in elderly trauma patients.

Introduction: The elderly population is growing worldwide and is more likely to die from injuries that younger patients would likely survive. Furthermore, elderly trauma patients are often subjected to triage decisions that admit them to lower-level facilities. These patients may require interhospital transfer to a major trauma center for definitive care.

Cocaine versus xylometazoline to prevent epistaxis after nasotracheal intubation: A randomized trial.

Background: Nasotracheal intubation is associated with a risk of epistaxis. Several drugs, including cocaine and xylometazoline may be used as decongestants prior to nasotracheal intubation to prevent this. We hypothesized that xylometazoline would prevent epistaxis more effectively than cocaine, demonstrated by a lower proportion of patients with bleeding after nasotracheal intubation.

Onset time, duration of action, and intubating conditions after mivacurium in elderly and younger patients.

Background: The neuromuscular blocking agent mivacurium can be used during anesthesia to facilitate tracheal intubation. Data on onset time, duration of action, and effect on intubating conditions in patients 80 years and older are however limited. We hypothesized that onset time and duration of action of mivacurium would be longer in elderly patients than in younger adults.

Perceptions of medical students on narrow learning objectives and structured debriefing in medical escape rooms: a qualitative study.

Background: Escape rooms are increasingly used in medical education as a complementary learning technique or even alternative to traditional educational approaches. Few studies focus on debriefing following medical escape rooms and how escape rooms can be used to achieve pre-defined learning objectives. Evaluating the use of narrow learning objectives may increase the depth of reflections and transform an engaging team event into an effective learning opportunity.

Rendezvous between ambulances and prehospital physicians in the Capital Region of Denmark: a descriptive study.

Background: In a two-tier Emergency Medical Services response system with ambulances and physician-staffed rapid response vehicles, both units are ideally dispatched simultaneously when a physician is needed. However, when advanced resources are dispatched secondarily, a meeting point (rendezvous) is established to reduce time to advanced care. This study aims to assess the extent of rendezvous tasks, patient groups involved and physician contribution when rendezvous is activated between the primary ambulances and rapid response vehicles in the Capital Region of Denmark.

Live video from bystanders' smartphones to improve cardiopulmonary resuscitation.

Aim: To investigate whether live video streaming from the bystander's smartphone to a medical dispatcher can improve the quality of bystander cardiopulmonary resuscitation (CPR) in out-of-hospital cardiac arrest (OHCA).

Methods: After CPR was initiated, live video was added to the communication by the medical dispatcher using smartphone technology. From the video recordings, we subjectively evaluated changes in CPR quality after themedical dispatcher had used live video to dispatcher-assisted CPR (DA-CPR).

Injury from electric scooters in Copenhagen: a retrospective cohort study.

Objective: To analyse injuries related to manual and electric scooter use from January 2016 up to and including July 2019.

Setting: Electric scooter rental services were launched in Denmark in January 2019. The services were provided by private companies.

Priming healthcare students on the importance of non-technical skills in healthcare: How to set up a medical escape room game experience.

Non-technical skills (NTS) are essential for healthcare professionals. Earlier the students are made aware of this, the more time they have to acquire these skills. Escape rooms have been introduced in the medical literature but a detailed published manual on setting up and running such a learning modality is lacking.