Influence of Glucose on the Self-Assembly and Photophysical Properties of Hydrophilic Pluronic F98.

This study investigates the effect of glucose, a kosmotropic osmolyte, on the micellization and hydration dynamics of the highly hydrophilic triblock copolymer (BCP), Pluronic F98. The outcomes obtained from the physicochemical studies are described. Clouding behavior demonstrated that increasing glucose concentration decreases the CP, highlighting a sugaring-out effect.

Self-Associated Engineering in P123 Micelles Rationalizing the Role of Other Pluronics with Varying Hydrophilicity as a Mixed System.

This study explores the atomic-level interactions of different poly(ethylene oxide) (EO)-poly(propylene oxide) (PO)-based block copolymers (BCPs), commercially known as Pluronics, with varying hydrophilicity that influences the solution behavior within Pluronic P123 micelles as a mixed system. The critical insights into the thermoresponsiveness of P123 in the presence of different Pluronics with increasing %EO content (L61, L62, L64, and F68) is hypothesized to modulate the hydrophobic interactions, leading to distinct solution textures such as clear solution (sol), blue point (BP), and cloud point (CP). The solution relative viscosity (η) and rheological analysis will depict the dynamic flow behavior and expose the viscoelastic properties of the blended system.

Role of Unimers to Polymersomes Transition in Pluronic Blends for Controlled and Designated Drug Conveyance.

This study investigates the nanoscale self-assembly from mixtures of two symmetrical poly(ethylene oxide)-poly(propylene oxide)-pol(ethylene oxide) (PEO-PPO-PEO) block copolymers (BCPs) with different lengths of PEO blocks and similar PPO blocks. The blended BCPs (commercially known as Pluronic F88 and L81, with 80 and 10% PEO, respectively) exhibited rich phase behavior in an aqueous solution. The relative viscosity (η) indicated significant variations in the flow behavior, ranging from fluidic to viscous, thereby suggesting a possible micellar growth or morphological transition.

Salt induced micellization conduct in PEO-PPO-PEO-based block copolymers: a thermo-responsive approach.

The nanoscale self-assembly behavior in ethylene oxide (EO) and propylene oxide (PO)-based block copolymers (BCPs) commercially available as Pluronics®: L44 (PEO-PPO-PEO) and F77 (PEO-PPO-PEO) is put forth in aqueous solution and in the presence of sodium salts NaCl and NaSO. The moderate hydrophilicity of L44 is attributed to its low molecular weight PPO segment, while the high percentage of PEO content in F77 contributes to its extreme hydrophilicity. The impact of sodium salts (NaCl and NaSO) on the self-assembly is investigated to understand their influence and role in micellization, by employing various physicochemical techniques such as phase behavior conduct, calorimetry, tensiometry, scattering, and spectral analysis.