Publications by authors named "Nistha Thakur"

Recently, functional materials derived from carbohydrate polymers have gained significant attention for their clinical uses due to their inherent bioactivity and biocompatibility. Therefore, the primary focus of the present research was to design bioactive moringa gum (MOGUM)-based hydrogels through covalent and supra-molecular interactions for use in biomedical applications. The copolymeric hydrogels were prepared by crosslinking of zwitterionic polymers of 2-(methacryloyloxy)ethyl] dimethyl-(3-sulfoproyl) ammonium hydroxide (MEDSAH) and carbopol (CP) onto gum for their applications in hydrogel wound dressings (HWDR) and drug delivery (DD).

View Article and Find Full Text PDF

Recently, significant progress has been made in the development of natural polysaccharide-derived functional copolymers for advanced biomedical uses. Herein, the main objective of the present research work was to explore the potential of gum acacia (GA) and tragacanth gum (TG) for developing network hydrogels to use in drug delivery (DD) applications. The copolymers were prepared by grafting of 3-sulfopropylacrlate (SPA) onto gum (GA-TG).

View Article and Find Full Text PDF

Recently, various efforts have been made to explore the potential of natural polysaccharides derived from sea weeds to promote sustainable development. Herein, carrageenan (CG), a polysaccharide extracted from red sea algae, was utilized to design network structures as hydrogels, aimed at significant applications in drug delivery (DD) systems. Hydrogels were designed by graft copolymerization reaction of poly(bis [2-methacryloyloxy] ethyl phosphate [poly(BMEP)] and poly(acrylic acid) [poly(AAc)] onto CG in the presence of a crosslinking agent.

View Article and Find Full Text PDF

The present work deals with the evaluation of the physiochemical and biomedical properties of hydrogels derived from copolymerization of tragacanth gum (TG) and gelatin for use in drug delivery (DD) applications. Copolymers were characterized by field emission-scanning electron micrographs (FE-SEM), electron dispersion X-ray analysis (EDAX), Fourier transform infrared spectroscopy (FTIR), C-nuclear magnetic resonance (NMR), thermo-gravimetric analysis (TGA), differential scanning calorimetry (DSC) and X-ray diffraction (XRD) analysis. FE-SEM revealed heterogeneous morphology and XRD analysis demonstrated an amorphous nature with short range pattern of polymer chains within the copolymers.

View Article and Find Full Text PDF