Acne vulgaris is an inflammatory and multifactorial skin disease involving the sebaceous gland and the skin microbiome. Different exposome factors, including hormonal and family factors, have been suggested to influence acne. Obesity is an increasingly observed condition worldwide, and is considered as a public health problem by the World Health Organization.
View Article and Find Full Text PDFActa Derm Venereol
April 2025
Acne-induced post-inflammatory hyperpigmentation (AI-PIH) can occur without any visible clinical evidence of significant inflammation, even in patients with mild to moderate acne. Currently, visual assessment is the main criterion for evaluating the severity of PIH, including that of AI-PIH in daily clinical practice. Treatment indications are lacking.
View Article and Find Full Text PDFEur J Dermatol
February 2025
Until recently, interest in truncal acne has been low, resulting in only a small amount of published data, focussing mainly on therapeutic options previously developed for facial acne. This report provides a summary of the work carried out since 2020 on truncal acne by a group of experts in acne. The expert group reviewed their own studies as well as more recently published articles on truncal acne and its management in daily clinical practice.
View Article and Find Full Text PDFAcne is one of the most frequent dermatoses in adolescents and young adults. If left untreated, it may cause physical and psychological scars. The growing lack of dermatologists results in delayed appointments, which increases these risks.
View Article and Find Full Text PDFIn transmen (women to men), the testosterone (T) therapy used to support the masculinizing process may cause acne. Conversely, in transwomen (men to women), feminising hormones may reduce acne but cause skin dryness and irritation which may be further exacerbated if mild acne persists, requiring topical treatments. Gonadotropin-releasing hormone analogues suppress endogenous sex hormones, thus avoiding the onset of acne in prepubertal individuals.
View Article and Find Full Text PDFActa Derm Venereol
March 2023
No epidemiological information about truncal acne is available. This study assessed the self-reported impact of truncal acne in adolescents and young adults, using an internet survey in France in 1,001 adolescents and young adults with truncal acne. Participants' mean age was 18.
View Article and Find Full Text PDFThe principal actors in acne are the sebaceous gland, keratinocytes of the follicle and skin microbiome/innate immunity. Current acne treatments are frequently accompanied by side effects or may cause antibacterial resistance. New formulations and emerging treatments with novel mechanisms of action and improved formulations have recently been made available or are currently under development.
View Article and Find Full Text PDFBackground: Cutibacterium acnes has been identified as one of the main triggers of acne. However, increasing knowledge of the human skin microbiome raises questions about the role of other skin commensals, such as Staphylococcus epidermidis, in the physiopathology of this skin disease.
Summary: This review provides an overview of current knowledge of the potential role of S.
Acne fulminans (AF) is a rare manifestation and the most severe form of the entire clinical spectrum of acne. The disease is destructive and is characterized by the sudden onset of painful and ulcerative pustules and systemic symptoms including high fever, hepatomegaly, polyarthralgia, leukocytosis, plaquetose, and increased inflammatory markers and transaminases. Osteolytic lesions in multiple skeletal sites could also be associated.
View Article and Find Full Text PDFActa Derm Venereol
September 2011
Acne can have an important psychological impact. We surveyed 852 adolescents aged 12-25 years about their knowledge of acne and its treatment in a non-medical context. The study involved a questionnaire administered to callers to a youth telephone helpline in France.
View Article and Find Full Text PDFMycobacterium abscessus is a species of rapidly growing mycobacteria (RGM). This species can cause skin and soft tissue infections after trauma or surgical procedures, pulmonary infections and disseminated diseases in immunocompromised patients. It has been rarely documented after tattoo procedures.
View Article and Find Full Text PDFExisting scoring systems for facial acne focus on the lesions themselves, but clinical decisions are based on a general assessment of severity, including the time since onset, the site(s) of involvement, the patient's history, and the response to prior treatments. The aim of this study was to investigate the influence of some of these factors on the global assessment of acne severity. Involvement of the trunk, prior systemic treatment and a positive family history of acne increased the severity score.
View Article and Find Full Text PDFThe topical treatment of acne has a great place in the therapeutic range of products which is available. It can be prescribed alone in moderate acne in most of cases, or in combination with an oral treatment in diffuse or severe acne. Last years formulations have improved with a better penetration and tolerance and therefore a better compliance and efficiency.
View Article and Find Full Text PDF