Pathogenicity of spp. Against : Effects on Immune Enzyme Activities and Gene Expression Profile.

(1) Background: spp. are fungi known for producing cyclosporin A and their ability to infect insects. However, their pathogenicity against the lepidopteran pest has not been previously reported.

Rituximab, tacrolimus, cyclophosphamide and cyclosporin in primary membranous nephropathy with nephrotic syndrome: comparison of safety profiles, effect on remission rate, 24-h urinary total protein, serum albumin, and serum creatinine levels using network meta-analysis.

Objective: To compare the efficacy and safety of four immunosuppressive therapies, either alone or in combination, for primary membranous nephropathy through a network meta-analysis.

Methods: A literature search was conducted for randomized controlled trials (RCTs) of Cyclophosphamide (CTX), Cyclosporin (CsA), Tacrolimus (TAC), and Rituximab (RIT) in the treatment of primary membranous nephropathy. Two researchers independently screened articles, extracted data, and evaluated the quality.

Saliva of (Drepanosiphidae) Activates the SA Plant Hormone Pathway, Inhibits the JA Plant Hormone Pathway, and Improves Aphid Survival Rate.

The spotted alfalfa aphid () is a kind of destructive pest of cultivated alfalfa () that results in significant financial losses for the livestock sector. To understand how navigates the biochemical defenses of its host, we investigated the effects of susceptible and resistant aphid strains on two alfalfa cultivars. was reared for over 50 generations on two cultivars-WL343, which is susceptible to , and Zhongmu No.

The Conserved Cysteine-Rich Secretory Protein MaCFEM85 Interacts with MsWAK16 to Activate Plant Defenses.

is an entomopathogenic fungus which may enhance plant growth and resistance when acting as an endophyte in host plants. However, little is known about the protein interactions nor their activating mechanisms. Common in fungal extracellular membrane (CFEM) proteins have been identified as plant immune regulators that suppress or activate plant resistance responses.

Kruppel Like Factor 5 Enhances High Glucose-Induced Renal Tubular Epithelial Cell Transdifferentiation in Diabetic Nephropathy.

Background - Diabetic nephropathy (DN) is a principal reason for kidney disease worldwide. High glucose (HG) is a major factor for DN. Kruppel like factor 5 (KLF5) participates in DN development.

Bioinformatics Analysis and Functional Characterization of the CFEM Proteins of .

The entomopathogen is a facultative rhizosphere or endophytic fungus available for managing pests and improving plant growth. The CFEM (common in fungal extracellular membrane) proteins form a unique group in fungi but are rarely reported in entomopathogens. In this study, we cloned and identified 13 CFEM genes from (MaCFEMs).

Identification of the key genes involved in the regulation of symbiotic pathways induced by in peanut () roots.

We detected and compared the mRNA and protein expression levels of immunity-associated and symbiosis-associated genes in peanut () roots inoculated with entomopathogenic fungus or the phytopathogenic fungus , by RT-qPCR and parallel reaction monitoring (PRM). The selected genes were mainly associated with plant-fungus interactions, signal transduction, regulation of cell death, nitrogen or iron metabolism, nutrient acquisition or transport, and compound synthesis based on previous transcriptome analysis. The results showed that the host basal defense responses were significantly inhibited by both and , which suggests that both fungi actively suppress the host immunity for successful colonization and infection.

Influence of Metarhizium anisopliae (IMI330189) and Mad1 protein on enzymatic activities and Toll-related genes of migratory locust.

Efficacy of Metarhizium anisopliae strain (IMI330189) and Mad1 protein alone or in combination by feeding method to overcome immune-related enzymes and Toll-like pathway genes was investigated in migratory locust. M. anisopliae (IMI330189) is a potent and entomopathogenic fungal strain could be effectively used against insect pests.