BACKGROUND Epinephrine for anaphylactic shock is the standard life-saving treatment in the emergency department. Cardiac symptoms after epinephrine administration in a child with no prior cardiac history are often not suspected. We describe a presentation of diastolic cardiac dysfunction after anaphylaxis from a bee sting in an adolescent male.
View Article and Find Full Text PDFPediatr Crit Care Med
September 2018
Objectives: To date, there are no published guidelines to direct RBC transfusion decision-making specifically for critically ill children. We present the recommendations from the Pediatric Critical Care Transfusion and Anemia Expertise Initiative.
Design: Consensus conference series of multidisciplinary, international experts in RBC transfusion management of critically ill children.
Objectives: To present the recommendations and supporting literature for RBC transfusions in critically ill children with bleeding developed by the Pediatric Critical Care Transfusion and Anemia Expertise Initiative.
Design: Consensus conference series of international, multidisciplinary experts in RBC transfusion management of critically ill children.
Methods: The panel of 38 experts developed evidence-based and, when evidence was lacking, expert-based clinical recommendations as well as research priorities for RBC transfusions in critically ill children.
Pediatr Crit Care Med
May 2018
Objectives: To determine the prevailing hemoglobin levels in PICU patients, and any potential correlates.
Design: Post hoc analysis of prospective multicenter observational data.
Settings: Fifty-nine PICUs in seven countries.
Ann Pharmacother
December 2017
Iron Deficiency in children is common problem. Its mechanism could be nutritional or due to lack of iron absorption. Several conditions are associated with IDA.
View Article and Find Full Text PDFPediatr Crit Care Med
September 2014
Objective: To describe packed RBC utilization patterns in trauma patients admitted to a PICU and study associated outcomes while controlling for severity.
Design: Retrospective cohort study.
Setting: The PICU of a tertiary care children's hospital.
Objectives: To evaluate the safety of deep sedation provided by pediatric intensivists for elective nonintubated esophagogastroduodenoscopy.
Design: Retrospective observational study.
Setting: The sedation program at the Helen DeVos Children's Hospital.
Objectives: Secondary hemophagocytic lymphohistiocytosis, macrophage activating syndrome, and sepsis share the same inflammatory phenotype leading often to multiple organ dysfunction syndrome needing intensive care. The goal of this article is to describe our experience with anakinra (Kineret), a recombinant interleukin-1 receptor antagonist, in decreasing the systemic inflammation.
Design: Retrospective case series.
Aims: Spinal deformity surgery is one of the most complicated procedures performed in pediatric orthopedics. These surgeries can account for long operative times and blood losses. Finding ways to limit patient morbidity undergoing these procedures may benefit many.
View Article and Find Full Text PDFBackground: Hematopoietic stem-cell transplant (HSCT) is associated with many risk factors for life-threatening complications. Post-transplant critical illness often requires admission to the pediatric intensive care unit (PICU).
Methods: A retrospective analysis was made on the risk factors associated with PICU admission and mortality of all HSCT patients at Helen DeVos Children's Hospital from October 1998 to November 2008.
Objectives: Intermittent bolus propofol is an effective agent for pediatric magnetic resonance imaging sedation but requires constant vigilance and dose titration. Magnetic resonance imaging-compatible infusion pumps may make it possible to continuously infuse propofol, achieving a steady level of sedation at a lower total dose. This study investigates total propofol dose, recovery time, and magnetic resonance image quality in children receiving intermittent vs.
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