Microorganisms play a key role in ruminal digestion, some of which can be used as probiotics to promote growth in ruminants. However, which potential bacteria are responsible for ruminant growth and how they potentiate the basic mechanism is unclear. In this study, three bacterial strains, (SN-3), (SN-6), and (SN-20) with multiple digestive enzymes were isolated from the rumen of healthy buffaloes.
View Article and Find Full Text PDFJ Ayub Med Coll Abbottabad
November 2022
Klippel-Feil syndrome (KFS) is the congenital fusion of two or more cervical vertebrae which is often associated with various other abnormalities in the cervical spine. Involvement the upper cervical segments leads to atlanto-axial instability which manifests as progressive neurological symptoms due to compression on the spinal cord. These cases pose a surgical challenge due the abnormal and unique anatomy of each patient.
View Article and Find Full Text PDFPhenolic acids (PAs) are one of the utmost prevalent classes of plant-derived bioactive chemicals. They have a specific taste and odor, and are found in numerous medicinal and food plants, such as L., (L.
View Article and Find Full Text PDFComp Biochem Physiol C Toxicol Pharmacol
February 2023
Depression is a common mental disorder that can adversely affect psychosocial function and quality of life. However, the exact aetiology and pathogenesis of depression are still unclear. Stress plays a major role in the pathogenesis of depression.
View Article and Find Full Text PDFTotal knee arthroplasty is gaining popularity in individuals with advanced stages of knee osteoarthritis among the affording economic class. The aim of the study was to assess the effects of preoperative rehabilitation in the management of post-operative quadriceps lag. The study design was non-randomised clinical study conducted from January 2017 to March 2017 at Ghurki Trust Teaching Hospital, Lahore, Pakistan.
View Article and Find Full Text PDFDrawing upon the conservation of resource theory (COR), this study proposes a moderated mediation model of authoritarian leadership on subordinates' cyberloafing. Paired samples of 360 employees working in 103 teams from Chinese companies were collected at 2 points in time. The results show that authoritarian leadership positively affects subordinates' cyberloafing and this relationship is mediated by emotional exhaustion.
View Article and Find Full Text PDFCordia rothii Roem. & Schult. possesses various beneficial effects and is traditionally used in folk medicine against liver diseases but its molecular mechanism remains unclear.
View Article and Find Full Text PDFFront Pharmacol
September 2022
Daphnetin (DAP), a coumarin derivative extracted from Daphne species, is biologically active phytochemical with copious bioactivities including anti-inflammatory, anti-oxidant, neuroprotective, analgesic, anti-pyretic, anti-malarial, anti-bacterial, anti-arthritic, neuroprotective, hepatoprotective, nephroprotective, and anti-cancer activities. A wide range of studies have been conducted exploring the significance and therapeutic potential of DAP. This study reviewed various databases such as NCBI, PubMed, Web of Science, Scopus and Google Scholar for published research articles regarding the sources, synthesis, and various bioactivities of DAP using different key words, including but not limited to "pharmacological activities," "sources," "neuroprotective effect," "synthesis," "cancer," "anti-inflammatory effect" of "daphnetin.
View Article and Find Full Text PDFClimate change has increasingly been recognised and associated with consumer behaviour: Practitioners are developing their strategies to reduce environmental degradation while increasing the management of sustainable consumption; it needs to better understand consumer attitudes and eco-friendly factors about the issue. Therefore, the current study focused to understand the effects of pro-environmental factors on individuals' environmental attitudes (purchase behaviour towards products with recycled packaging) through the lens of theory of planned behaviour in a cross-cultural setting. Moreover, present research focuses on the moderating role that religiosity plays in causal pathways between certain determinants (attitude, subjective norms, and perceived behavioural control) and intentions in this context.
View Article and Find Full Text PDFPresent research was planned to assess the in vitro and in vivo anti-arthritic potential of Caralluma tuberculata N. E. Brown.
View Article and Find Full Text PDFImportance: Transcutaneous osseointegration post amputation (TOPA) creates a direct linkage between residual bone and an external prosthetic limb, providing superior mobility and quality of life compared with a socket prosthesis. The causes and potential risks of mortality after TOPA have not been investigated.
Objective: To investigate the association between TOPA and mortality and assess the potential risk factors.
Meloxicam (MEL) is an oxicam derivative with low water solubility that is useful in the treatment of colorectal cancer (CRC) as a COX-2 inhibitor. MEL-loaded HPMC micro particles were fabricated using an oil-in-oil (o/o) emulsion solvent evaporation (ESE) method. FTIR, XRD, particle size analysis, DSC, SEM and in vitro dissolution investigation were utilized to evaluate the produced micro particles physiochemically.
View Article and Find Full Text PDFEvid Based Complement Alternat Med
September 2022
The aim of the present study was to evaluate the antioxidant and antidiabetic potential of Indian olive seed extracts. Plant seeds were sequentially extracted with n-hexane, chloroform, methanol, and water. 2,2-Diphenyl-1-picrylhydrazyl (DPPH) scavenging and alpha-amylase inhibitory activities of extracts were carried out.
View Article and Find Full Text PDFArsenic exposure is associated with the induction of hepatotoxicity. Current study was aimed to investigate the hepato-protective ability of polyphenolic components of Tamarix aphylla (TA) ethanolic extract against sodium arsenite (SA)-induced liver injury of rats. Significantly higher quantities of phenolic (318.
View Article and Find Full Text PDFPollution harms ecosystems and poses a serious threat to human health around the world through direct or indirect effects on air, water, and land. The importance of remediating effluents is paramount to reducing environmental concerns. CO emissions are removed efficiently and efficaciously with mixed matrix membranes (MMMs), which are viable replacements for less efficient and costly membranes.
View Article and Find Full Text PDFNon availability of effective anti-TB vaccine impedes TB control which remains a crucial global health issue. A fusion molecule based on immunogenic antigens specific to different growth phases of Mycobacterium tuberculosis can enhance T-cell responses required for developing a potent vaccine. In this study, six antigens including EspC, TB10.
View Article and Find Full Text PDFMastitis is an emerging health concern in animals. An increased incidence of mastitis in dairy cows has been reported in the last few years across the world. It is estimated that up to 20% of cows are suffering from mastitis, causing incompetency in the mucosal immunity and resulting in excessive global economic losses in the dairy industry.
View Article and Find Full Text PDFPterostilbene is a stilbene flavonoid that occurs naturally in various plants as well as produced by genetic engineering. It exhibits anti-inflammatory, analgesic, anti-oxidant and neuroprotective activities. This research was aimed to determine the potential of pterostilbene against arthritis and peripheral neuropathy in Complete Freund's Adjuvant (CFA) induced arthritis.
View Article and Find Full Text PDFAntimicrobial peptides (AMPs) are considered to be powerful weapons in the fight against traditional antibiotic resistance due to their unique membrane-disruptive mechanism. The combination of traditional and classical hydrophobic tryptophan (W) residues and hydrophilic charged arginine (R) residues is considered as the first choice for the minimalist design of AMPs due to its potent performance in antibacterial activity. However, some W- and R-rich AMPs that are not rationally designed and contain excessive repeats of W and R residues may cause severe cytotoxicity and hemolysis.
View Article and Find Full Text PDFHerbal drugs offer an alternative approach for the treatment of diseases like asthma due to low cost and comparatively less adverse effects in contrast to synthetic drugs. Leaves of Quercus leucotrichophora are traditionally used for the treatment of asthma. The study was aimed to assess the anti-asthmatic activity of Quercus leucotrichophora (QL) methanolic (QLME) and aqueous extracts (QLAE) in ovalbumin-(OVA) induced asthma and chemical characterization of QL extract by High Performance Liquid Chromatography-Diode array detector (HPLC-DAD).
View Article and Find Full Text PDFJ Pharm Anal
August 2022
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View Article and Find Full Text PDFThe search for renewable resources that can replace petroleum products is not only nerve-wracking, but also perplexing, as there is an abundance of plants that have yet to be explored. In this project, virgin castor oil was converted to polyol in two steps: epoxidation and hydroxylation. The resulting polyol was used to synthesize two series of water-borne polyurethane dispersions (WPUDs).
View Article and Find Full Text PDFAnimals (Basel)
September 2022
Sperm cryopreservation is one of the sublime biotechnologies for assisted reproduction. In recent decades, there has been an increasing trend in the use of preserved semen. Post-thaw semen quality and values vary among animals of the same species.
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