A comparative analysis of gender and racial disparities in acute necrotizing pancreatitis outcomes: Insights from the national inpatient sample database.

Background/objectives: Acute Necrotizing pancreatitis (NP), a severe form of pancreatitis, carries high morbidity and mortality, with outcomes influenced by patient demographics. While prior research highlights disparities in gastrointestinal diseases, the impact of race and gender on NP outcomes remains underexplored. This study evaluates the influence of these demographic factors on in-hospital mortality, complications, length of stay (LOS), and hospitalization costs.

Hypothermic Oxygenated Perfusion Versus Static Cold Storage in Transplantation of Extended Criteria Liver Grafts: A Systematic Review and Meta-Analysis.

Background: The use of extended criteria donor livers (ECD) is becoming more routine in many transplant centers. These organs have higher risks for complications; however, hypothermic-oxygenated perfusion (HOPE) was found to improve outcomes, including graft survival. We aim to assess the effect of HOPE on different types of ECD liver grafts.

A rare case report of mucormycosis presenting as cranial nerve palsies in a patient with diabetes and iatrogenic cushing syndrome.

Rationale: Mucormycosis is a rare opportunistic fungal infection caused by mucormycetes, primarily affecting immunocompromised individuals such as diabetic patients. Cranial nerve involvement, including facial and abducens nerve palsies, is an uncommon but serious complication.

Patient Concerns: We present the case of a 47-year-old female with uncontrolled diabetes and iatrogenic Cushing's syndrome who developed mucormycosis complicated by right-sided facial weakness (upper motor neuron type) and abducens nerve palsy (lower motor neuron type).

Impact of Foliar Spray of Salicylic Acid on Morpho-Physiological and Biochemical Responses of Pea (Pisum sativum L.) under Drought Stress.

Drought stress reduces growth, yield, and photosynthetic efficiency in pea plants, limiting nutrient uptake and requiring mitigation strategies. Salicylic acid plays a key role in plant development, and pea (Pisum sativum L.) ranks fourth in global production.

Brain tumor segmentation by optimizing deep learning U-Net model.

BackgroundMagnetic Resonance Imaging (MRI) is a cornerstone in diagnosing brain tumors. However, the complex nature of these tumors makes accurate segmentation in MRI images a demanding task.ObjectiveAccurate brain tumor segmentation remains a critical challenge in medical image analysis, with early detection crucial for improving patient outcomes.

Unveiling genetic diversity and population structure in lentil (Lens culinaris) germplasm through scot markers.

Background: Lentil (Lens culinaris) is extensively cultivated for its edible seeds and plays an important role in food security and sustainable agriculture. Understanding the genetic diversity and population structure of lentil germplasm is crucial for breeding programs and for effective conservation of genetic resources.

Methods And Results: In this study, the genetic variation and population structure of 96 lentil accessions were assessed using Start Codon Targeted (SCoT) markers.

A New Era of Decision-making in Liver Transplantation: A Prospective Validation and Cost-effectiveness Analysis of FMN-guided Liver Viability Assessment During Normothermic Machine Perfusion.

Objectives: Flavin mononucleotide (FMN), a marker of mitochondrial complex 1 injury, has not yet been validated for its predictive value of outcomes and economic impact.

Background: Normothermic machine perfusion (NMP) is the only ex situ perfusion technique currently approved for liver transplantation in the United States. Optimal graft viability assessment on this approach remains controversial.

Effect of dexamethasone and lidocaine combination on incidence of post-operative sore throat: A meta-analysis and trial sequential analysis.

Background: Postoperative sore throat (POST) is a common complication after endotracheal intubation, occurring in 30-50 % of patients. While lidocaine (local anesthetic) and dexamethasone (anti-inflammatory) are used individually to prevent POST, their combined efficacy remains unclear. This meta-analysis synthesizes evidence from randomized controlled trials to determine whether Intravenous dexamethasone-lidocaine combination is more effective than dexamethasone alone in reducing POST incidence.

Genome-wide association study of common bean (Phaseolus vulgaris L.) unveils novel loci governing root-to-seed zinc allocation.

Micronutrient malnutrition is a global health concern, highlighting the importance of essential micronutrients like zinc in human diet, and enhancing zinc concentration in staple crops like common beans is a promising strategy. In this study, we performed genome-wide association studies to identify genetic loci associated with Zn accumulation in a diverse panel of 177 Turkish common bean landraces and six commercial varieties. Field trials were conducted across two locations over two years to assess Zn concentration variation.

Temporal Trends in Mortality Location Among Patients With Intrahepatic Cholangiocarcinoma in the USA: A Retrospective Observational Analysis of National Center for Health Statistics Mortality Data.

Objectives: Intrahepatic cholangiocarcinoma (ICC) is a malignancy with rising incidence and mortality in the United States. This study aimed to investigate temporal trends in the place of death among patients with ICC and assess demographic disparities.

Methods: We used the CDC WONDER database (2003-2020) for a retrospective study of patients who died from intrahepatic cholangiocarcinoma identified through death certificates.

Normothermic machine perfusion in liver transplantation: a bibliometric analysis of the top 100 most cited articles.

Background: Normothermic machine perfusion (NMP) has increased substantially in the recent decade, being a vital tool in further organ preservation and reducing ischemia-reperfusion injury. The purpose of this study was to objectively conduct a bibliometric analysis of the top 100 cited articles to understand the evolution of NMP in liver transplantation.

Methods: Scopus was selected as our primary database.

Large Language Models in Gastroenterology and Gastrointestinal Surgery: A New Frontier in Patient Communication and Education.

When integrated into healthcare, large language models (LLMs) have transformative and revolutionary effects, including significant potential for improving patient care and streamlining clinical processes. However, one specialty that particularly requires data on LLM use is gastroenterology and gastrointestinal surgery, a gap we sought to address in our research. Advanced artificial intelligence (AI) systems like LLMs have demonstrated the ability to mimic human communication, assist in diagnosis, provide patient education, and support medical research simultaneously.

Shifting US location patterns in leukaemia mortality: retrospective analysis.

Objectives: Leukaemia is a haematological malignancy with high mortality, yet end-of-life care patterns remain underexplored. This study analysed trends in the place of death among leukaemia decedents and assessed demographic disparities in end-of-life care.

Methods: A retrospective observational study was conducted using the Centres for Disease Control and Prevention's WONDER and National Center for Health Statistics mortality databases (2008-2020).

Population structure, genetic diversity, and GWAS analyses with GBS-derived SNPs and silicodart markers unveil genetic potential for breeding and candidate genes for agronomic and root quality traits in an international sugar beet germplasm collection.

Background: Knowledge about the degree of genetic diversity and population structure is crucial as it facilitates novel variations that can be used in breeding programs. Similarly, genome-wide association studies (GWAS) can reveal candidate genes controlling traits of interest. Sugar beet is a major industrial crops worldwide, generating 20% of the world's total sugar production.

Female gender and racial minority status is associated with Poor clinical outcomes and higher healthcare resource utilization in necrotizing fasciitis: Analysis of a Nationwide database in the United States.

Introduction: Necrotizing fasciitis is a rapidly progressive infection associated with high mortality and complications. It mainly involves subcutaneous tissue and fascia. More quality data on disparities in clinical outcomes of necrotizing fasciitis must be provided.

Identification of Phenotypic Diversity and DArTseq Loci Associated with Vitamin A Contents in Turkish Common Bean Germplasm Through GWAS.

Biofortification has emerged as an important approach for improving minerals and vitamin deficiencies through the application of agronomic and biotechnological methodologies. Vitamin A, one of the most deficient vitamins, disproportionately affects children in developing countries, highlighting the urgent need for vitamin A-enriched cultivars. The present study aimed to characterize common bean germplasm for vitamin A contents and to identify the genomic regions associated with this trait.

Extension of mindful safety practices through safety knowledge and safety motivation: a study of the aviation industry.

This article attempts to extend the mindful safety practices adopted by pilots in the aviation industry. There is still a lack of discussion about how these factors (individual, group and organizational levels) influence the adoption of mindful safety practices among commercial pilots in the aviation industry. Data were collected from a sample of commercial pilots in China within 8 months.

Genotyping-by-sequencing derived SNP markers reveal genetic diversity and population structure of germplasm.

Orchardgrass ( L.), a widely cultivated cool-season perennial, is an important forage crop due to its adaptability, high nutritional value, and substantial biomass. Understanding its genetic diversity and population structure is crucial for developing resilient cultivars that can withstand climate change, diseases, and resource limitations.

Green remediation of lead (pb) from Pb-toxic soil by combined use of silicon nanomaterials and leguminous Lens culinaris L. plants.

Lead (Pb) toxicity is a major issue due to anthropogenic activities that is faced by farmers nowadays which inhibits plant growth and decreases crop yields. From contaminated soils, Pb absorbed by the plants and then ultimately enters into the food chain. Silicon (Si) can reduce Pb availability to plants and can be helpful in Pb immobilization in the soils.

Oil Content and Fatty Acid Composition of Safflower ( L.) Germplasm.

Safflower ( L.) is a promising oilseed crop with potential applications in the food, pharmaceutical, and industrial sectors. Understanding the oil content and fatty acid composition of safflower germplasm is crucial for breeding programs aimed at enhancing its agronomic and nutritional traits.

Modern Plant Breeding Techniques in Crop Improvement and Genetic Diversity: From Molecular Markers and Gene Editing to Artificial Intelligence-A Critical Review.

With the development of new technologies in recent years, researchers have made significant progress in crop breeding. Modern breeding differs from traditional breeding because of great changes in technical means and breeding concepts. Whereas traditional breeding initially focused on high yields, modern breeding focuses on breeding orientations based on different crops' audiences or by-products.

The effects of psychological safety and employee voice behavior on flight attendants' mindful safety practices adoption.

Introduction: Flight attendants, as the front-line staff in the cabin, play a crucial role in improving air travel safety. This research explores how psychological safety affects flight attendants' adoption of mindful safety practices through voice participation. This mechanism also identifies ethical leadership and traditionality as two moderators.

DFT and comparative adsorption study of NiO, MnO, and MnNiO nanomaterials for the removal of amaranth dye from synthetic water.

In the current study, NiO nanoparticles, MnO nanoparticles, and MnNiO nanocomposites (Ni-NPs, Mn-NPs and MN-NCs, respectively) were synthesized using a facile hydrothermal method, and their performance in the removal of amaranth (AM) dye from synthetic wastewater was compared. XRD, FTIR spectroscopy, SEM, BET analysis, and TGA were performed to characterize the produced catalysts. The effect of pertinent parameters, including pH, dosage of catalysts, temperature, and shaking speed on the uptake of AM was investigated through batch experiments.