Publications by authors named "Mohammed Azab"

Background: The temporalis muscle is commonly dissected and mobilized during craniotomy. Cosmetic and functional complications may arise from the improper handling of this muscle. Surgery for recurrent pathologies may be challenging due to adhesions and muscle damage.

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Background: Meningothelial cells within the arachnoid of the Sylvian fissure give rise to a rare subtype of non-dural based tumors known as Sylvian fissure meningiomas (SFMs). The clinical presentations and management of these lesions need to be further explained.

Methods: We followed the PRISMA statement guidelines when reporting this systematic review and meta-analysis.

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Background: Several decades ago, cancer pain was treated with surgical and chemical adenolysis, and it was associated with several complications. Therefore, radiosurgery of the pituitary was reevaluated again for the potential use in managing medication refractory chronic pain.

Methods: A systematic review was conducted according to PRISMA guidelines using the PubMed, Scopus, Web of Science, Embase, and Cochrane Library databases to identify the studies that described pituitary stereotactic radiosurgery for the management of refractory pain.

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Interhemispheric subdural hematoma (ISH) poses significant challenges in neurosurgical practice owing to its deep localization within the cerebral hemispheres. Despite widespread adoption of advanced neurosurgical technologies, adverse patient outcomes hinder progress in enhancing overall prognosis. This review seeks to evaluate the etiology, clinical manifestations, treatment modalities, and outcomes associated with ISHs, thereby informing clinical decision-making and improving patient care.

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BackgroundMiddle meningeal artery (MMA) embolization is an increasingly common procedure involved in the treatment of various vascular and neoplastic diseases. Understanding its anatomical nuances and clinical implications is fundamental in enhancing the safety of preoperative embolization.MethodsA systematic review following PRISMA guidelines was conducted to consolidate literature on the MMA anomalous variations.

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Dissection methods are variable, and surgeons select the appropriate method based on its safety, efficiency and applicability. The water-jet dissection technique is a promising method that has been applied in different surgeries. We try to highlight the possible neurosurgical applications and evaluate the safety and efficacy of this technique.

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Background: Pineal cyst is an uncommon condition in pregnancy. It is often encountered as an incidental finding. Most pineal cysts are benign and asymptomatic.

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Introduction: Giant Serpentine Aneurysms (GSA) are a rare subgroup of complex intracranial vascular anomalies characterized by unusually large and convoluted structures within cerebral arteries. This systematic review examines the historical context, clinical presentations, diagnostic methodologies, and evolving treatments specific to GSAs. Its goal is to advance patient care strategies and outcomes within this intricate neurovascular domain.

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Decompressive craniectomy is a common neurosurgical procedure for cases of increased intracranial pressure. In patients undergoing cranioplasty, dissection planes are usually difficult to identify due to adhesions. We highlight the possible ways to make dissection easier in cranioplasty.

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Pericallosal artery aneurysms (PCAA) are relatively rare intracranial aneurysms that present unique challenges in diagnosis and management. This study provides a comprehensive review of the literature to assess demographic patterns, risk factors, treatment approaches, and complications associated with PCAA. Data from 23 studies were analyzed using Python with libraries such as Pandas and Matplotlib.

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Cerebral metastases from soft tissue and bone sarcoma are uncommon. Metastatic sarcoma of the brain is a highly aggressive disease with a poor prognosis. There is no consensus regarding the management of cerebral metastases from bone sarcomas.

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Intracranial aneurysms, with an annual incidence of 2%-3%, reflect a rare disease associated with significant mortality and morbidity risks when ruptured. Early detection, risk stratification of high-risk subgroups, and prediction of patient outcomes are important to treatment. Radiomics is an emerging field using the quantification of medical imaging to identify parameters beyond traditional radiology interpretation that may offer diagnostic or prognostic significance.

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Background: The pathogenesis, surgical techniques, and outcomes of pituitary adenomas (PAs) remain variable. We compared our surgical techniques and perioperative/long-term PA outcomes to highlight the hybrid microscopic/endoscopic technique used to optimize efficiency, cost savings, and outcomes in PA surgery.

Methods: Consecutive PA cases performed from January 2017 through February 2020 were evaluated retrospectively.

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Malignant melanotic nerve sheath tumors (MMNSTs), also known as a melanocytic schwannoma (MS), are a rare type of peripheral nerve sheath tumors including Schwann cells with melanocytic differentiation. Only a few cases of spinal MMNST have been reported in literature. Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography ( F-FDG-PET/CT) could be used to detect these lesions.

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Introduction: Idiopathic intracranial hypertension (IIH) is a neurological disorder characterised by elevated intracranial pressure (ICP), predominantly affecting obese women of reproductive age. While GLP-1 receptor agonists have shown promise in IIH management, the potential of dual GIP/GLP-1 receptor activation through tirzepatide remains unexplored. This study aimed to evaluate tirzepatide's efficacy as an adjunctive therapy in IIH management.

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Objective: Idiopathic intracranial hypertension (IIH) is a neurological disorder predominantly affecting young women with obesity, characterized by elevated intracranial pressure. While current treatments include weight loss counseling, medical therapies, and surgical interventions, their limitations necessitate exploring novel therapeutic approaches. We investigated the efficacy of liraglutide as an adjunctive therapy in IIH management.

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Objectives: Effective wound closure is essential to neurosurgical procedures. Historical rates of neurosurgical wound complications range from 7 to 14 %. Knotless suturing with barbed sutures may offer effective closure rates but has had limited evaluation of safety in neurosurgical applications.

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Introduction: Idiopathic intracranial hypertension (IIH) is known to elevate cardiovascular disease (CVD) risk, but the extent to which obesity and IIH-specific factors contribute to this risk is not well understood. WE aim to separate the effects of obesity from IIH-specific factors on the risk of stroke and CVD, building on previous findings that indicate a two-fold increase in cardiovascular events in women with IIH compared to BMI-matched controls.

Methods: An obesity-adjusted risk analysis was conducted using Indirect Standardization based on data from a cohort study by Adderley et al.

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This study aimed to provide an updated evidence of superior hypophyseal artery (SHA) aneurysms management, including their clinical implications, predictive factors for rupture, therapeutic approaches, and post-treatment outcomes. This systematic review and meta-analysis, following PRISMA guidelines, assessed the literature on superior hypophyseal artery aneurysms. Studies were selected based on predefined criteria, focusing on coiling and clipping interventions.

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Introduction: Managing idiopathic intracranial hypertension (IIH) is challenging due to limited treatment options. This study evaluates metformin as a potential therapy for IIH, examining its impact on disease outcomes and safety.

Methods: We performed a retrospective cohort study using the TriNetX database, covering data from 2009 to August 2024.

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Background: Lesions affecting the brain are variable and have multiple pathologies. Brain metastasis is a common entity of lesions that can be misleading in diagnosis. Brain metastasis affects the patient's life and survival in about 40% of cases; all patients with metastatic brain lesions are indicated for surgery, so proper diagnosis is crucial for each patient.

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Background: Idiopathic intracranial hypertension (IIH) is a neurological disorder characterized by elevated intracranial pressure, predominantly affecting young women with obesity. This study evaluates the effectiveness of semaglutide as an adjunctive therapy to standard IIH management using real-world data.

Methods: We conducted a retrospective cohort analysis comparing IIH patients receiving semaglutide plus standard therapy versus standard therapy alone.

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Introduction: Idiopathic intracranial hypertension (IIH) is a neurological disorder characterized by elevated intracranial pressure, predominantly affecting obese women of reproductive age. While GLP-1 receptor agonists have shown promise in IIH management, the potential of dual GIP/GLP-1 receptor activation through tirzepatide remains unexplored. This study aimed to evaluate tirzepatide's efficacy as an adjunctive therapy in IIH management.

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BackgroundPerianeurysmal edema occurring after endovascular treatment for cerebral aneurysms is uncommon compared to surgical clipping. The clinical aspects and the exact explanation are poorly understood.MethodsWe searched PubMed, Google Scholar, and Web of Science.

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Background: The use of fluorescein sodium (FS) as a surgical adjunct in glioblastoma resection has shown promise in improving tumor visualization and resection outcomes. This study aimed to evaluate the safety, efficacy, and side effects of FS-aided resection in patients with glioblastoma.

Methods: This is a prospective, single-center cohort study conducted at Ibrahim Cardiac Hospital and Research Institute from September 2021 to November 2023.

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