Publications by authors named "Melysze D Oorloff"

Background: Studies have shown that tirofiban (a glycoprotein IIb/IIIa receptor antagonist) is effective in the endovascular treatment of cerebrovascular diseases. However, it has also been reported that tirofiban can cause thrombocytopenia. Here we report a rare case of tirofiban-induced acute profound thrombocytopenia in a patient undergoing endovascular therapy for acute ischemic stroke.

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Article Synopsis
  • The study investigates the link between nutritional status, as measured by the Geriatric Nutritional Risk Index (GNRI), and cognitive function in older US adults, using data from the NHANES database.
  • The analysis involved nearly 3,000 individuals aged 60 and over, revealing that those categorized as malnourished (GNRI score ≤98) exhibited significantly lower scores in multiple cognitive assessments compared to those with normal nutrition (GNRI score >98).
  • The findings suggest that lower GNRI levels correlate with an increased risk of cognitive decline, particularly in elderly individuals with a history of stroke or other neurological issues.
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Background: Dyslipidemia is prominently associated with adverse outcomes in patients with coronary artery disease (CAD). The non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) is a novel comprehensive lipid index. However, limited evidence exists on the relationship of the NHHR with the risk of adverse outcomes in patients with CAD.

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Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal (GI) disorders in the world. Although IBS does not affect a person's life span, it can significantly influence their quality of life. The treatment of IBS should be tailored to each patient's specific symptomatology because it can often be difficult to manage.

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Background: Fahr's syndrome a rare neurological condition characterized by an abnormal basal ganglia calcification. The condition has both genetic and metabolic causes. Here, we describe a patient who had Fahr's syndrome and basal secondary to hypoparathyroidism, and her calcium level raised after the administration of steroid therapy.

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