Trends in Glycemic and Cardiovascular Risks Control in Cantonese Adults in Primary Healthcare Settings: 2018 to 2022.

Background: Glycemic and cardiovascular risks control in patients with type 2 diabetes (T2DM) managed in primary healthcare (PHC) settings remains challenging in urbanizing areas like Guangzhou. This study analyzes 2018-2022 trends to identify care gaps and inform policy.

Methods: We collected and analyzed real-world data (RWD) from 81,709 adults aged 30 years or older with T2DM who voluntarily participated in health examinations across 24 primary healthcare settings in Baiyun district, Guangzhou.

Lid wiper epitheliopathy: an early sign of dry eye diagnosis.

Objectives: The purpose of this study was to investigate the relationship between the severity of lid wiper epitheliopathy (LWE) and ocular surface features and evaluate the potential of LWE as an early diagnosis indicator of dry eye.

Methods: Eighty-eight patients diagnosed with dry eye by TFOS DEWS II were divided into two groups based on the Korb grading: the mild group and the moderate-severe group. Ocular assessments included examination of LWE, tear-film lipid layer thickness (LLT) measurement, partial blinking rate (PBR) calculation, fluorescein tear breakup time (FTBUT) measurement, determining corneal fluorescein staining score, eyelid margin score, and meiboscore.

Transcriptomics, single-cell sequencing and spatial sequencing-based studies of cerebral ischemia.

With high disability and mortality rate as well as highly complex pathogenesis, cerebral ischemia is highly morbid, prone to recurrence. To comprehensively understand the pathophysiological process of cerebral ischemia and to find new therapeutic strategies, a new approach to cerebral ischemia transcriptomics has emerged in recent years. By integrating data from multiple levels of transcriptomics, such as transcriptomics, single-cell transcriptomics, and spatial transcriptomics, this new approach can provide powerful help in revealing the molecular mechanisms of cerebral ischemia occurrence and development.

Efficacy of indirect intense pulsed light irradiation on meibomian gland dysfunction: a randomized controlled study.

Aim: To investigate the efficacy and mechanisms of indirect intense pulsed light (IPL) irradiation on meibomian gland dysfunction (MGD).

Methods: A total of 60 MGD patients was included in this prospective randomized controlled trial. Patients were randomly assigned 1:1 into two groups (3-mm group and 10-mm group) in which IPL was applied at distances from the lower eyelid margin of 3 and 10 mm, respectively.

Direct regeneration of LiFePO cathode by inherent impurities in spent lithium-ion batteries.

The direct regeneration method, recognized for its cost-effectiveness, has garnered considerable attentions in the field of battery recycling. In this study, a novel direct regeneration strategy is proposed to repair spent LiFePO (S-LFP) cathodes without the need for impurity removal. Instead, the residual conductive carbon and polyvinylidene fluoride (PVDF) in S-LFP are employed as inherent reductive agents.

Complete genome sequences of two Pantoea stewartii strains ATCC 8199 from maize and PSCN1 from sugarcane.

Objectives: The pathogen of Pantoea stewartii (Ps) is the causal agent of bacterial disease in corn and various graminaceous plants. Ps has two subspecies, Pantoea stewartii subsp. stewartia (Pss) and Pantoea stewartii subsp.

The effect of type 2 diabetes mellitus on lid wiper epitheliopathy and ocular surface parameters.

Introduction: This cross-sectional study was conducted to investigate the impact of type 2 diabetes mellitus(DM) and its duration on indicators such as lid wiper epitheliopathy(LWE), and to assess the significance of LWE for early diagnosis of dry eye disease(DED) in DM patients.

Methods: A total of 137 subjects with ocular surface disease index(OSDI) score ≥13 were divided into the non-DM group, the short-term DM group (duration <5 years), and the mid-to-long-term DM group(duration ≥5 years). Evaluations were conducted for LWE, OSDI, lipid layer thickness (LLT), partial blinking rate (PBR), fluorescein tear breakup time (FTBUT), corneal fluorescein staining score (CFS), eyelid margin score, and meibomian gland dropout (MGd).

Direct Regeneration of Spent Lithium-Ion Battery Cathodes: From Theoretical Study to Production Practice.

Direct regeneration method has been widely concerned by researchers in the field of battery recycling because of its advantages of in situ regeneration, short process and less pollutant emission. In this review, we firstly analyze the primary causes for the failure of three representative battery cathodes (lithium iron phosphate, layered lithium transition metal oxide and lithium cobalt oxide), targeting at illustrating their underlying regeneration mechanism and applicability. Efficient stripping of material from the collector to obtain pure cathode material has become a first challenge in recycling, for which we report several pretreatment methods currently available for subsequent regeneration processes.

Insulin eye drops improve corneal wound healing in STZ-induced diabetic mice by regulating corneal inflammation and neuropeptide release.

Introduction: In recent years, insulin eye drops have attracted increasing attention from researchers and ophthalmologists. The aim of this study was to investigate the efficacy and possible mechanism of action of insulin eye drops in diabetic mice with corneal wounds.

Methods: A type 1 diabetes model was induced, and a corneal epithelial injury model of 2.

Insights into Reactive Oxygen Species Production-Scavenging System Involved in Sugarcane Response to Infection under Drought Stress.

Plants must adapt to the complex effects of several stressors brought on by global warming, which may result in interaction and superposition effects between diverse stressors. Few reports are available on how drought stress affects () infection in sugarcane ( spp. hybrids).

Identification of a sugarcane bacilliform virus promoter that is activated by drought stress in plants.

Sugarcane (Saccharum spp.) is an important sugar and biofuel crop in the world. It is frequently subjected to drought stress, thus causing considerable economic losses.

Association between dyslipidaemia and dry eye disease: a systematic review and meta-analysis.

Purpose: To report a systematic review and meta-analysis of the association between dry eye disease (DED) and dyslipidaemia.

Methods: PubMed, Embase, Web of Science and Cochrane Library were systematically searched from January 2000 to December 2021. We included observational studies to assess the correlation of DED with meibomian gland dysfunction and dyslipidaemia without any language restrictions.

Identification of ARF transcription factor gene family and its defense responses to bacterial infection and salicylic acid treatment in sugarcane.

Auxin response factor (ARF) is a critical regulator in the auxin signaling pathway, involved in a variety of plant biological processes. Here, gene members of 24 and 39 were identified in two genomes of clones AP85-441 and Np-X, respectively. Phylogenetic analysis showed that all genes were clustered into four clades, which is identical to those genes in maize () and sorghum ().

Effect of prophylactic antiviral intervention on T cell immunity in hepatitis B virus-infected pregnant women.

Background: Antiviral intervention in hepatitis B virus (HBV)-infected pregnant women can effectively reduce mother-to-child transmission. However, the immunological characteristics of pregnant women with chronic HBV infection and the effects of antiviral intervention during pregnancy on maternal immune response remain unknown. We aimed to investigate these effects by comparing mothers who received antiviral intervention during pregnancy with those who did not.

Effects of borneol combined with astragaloside IV and Panax notoginseng saponins regulation of microglia polarization to promote neurogenesis after cerebral ischaemia.

Objective: To study the effect of borneol combined with astragaloside IV and Panax notoginseng saponins (BAP) on promoting neurogenesis by regulating microglia polarization after cerebral ischaemia-reperfusion(CI/R) in rats.

Methods: A focal CI/R injury model was established. Evaluated the effects of BAP on ischaemic brain injury, on promoting neurogenesis, on inhibiting Inflammatory microenvironment and TLR4/MyD88/NFκB signalling pathway.

Direct Electrochemical Leaching Method for High-Purity Lithium Recovery from Spent Lithium Batteries.

Recovering lithium from lithium batteries (LIBs) is a promising approach for sustainable ternary lithium battery (T-LIB) development. Current lithium recovery methods from spent T-LIBs mainly concentrated on chemical leaching methods. However, chemical leaching relying on the additional acid seriously threatens the global environment and nonselective leaching also leads to low Li recovery purity.

[Effect of FZU63 on the flavor quality of black tea beverage].

The tea beverages will be endowed with distinct aroma and taste, as well as various biologically active compounds including probiotic factors, when fermented with lactic acid bacteria (LAB). However, at present, few studies on the dynamics of flavors in tea soup at different fermentation stages were conducted. In this study, the composition of monosaccharides, aromatic components, free amino acids, and organic acids were measured, when the black tea beverages were fermented with FZU63 which was isolated from Chinese traditional kimchi.

Sugarcane responses to two strains of differing in pathogenicity through a differential modulation of salicylic acid and reactive oxygen species.

Leaf scald caused by is one of the major bacterial diseases of sugarcane that threaten the sugar industry worldwide. Pathogenic divergence among strains of and interactions with the sugarcane host remain largely unexplored. In this study, 40 strains of from China were distributed into three distinct evolutionary groups based on multilocus sequence analysis and simple sequence repeats loci markers.

Systematic and functional analysis of non-specific lipid transfer protein family genes in sugarcane under infection and salicylic acid treatment.

Plant non-specific lipid transfer proteins (nsLTPs) are small basic proteins that play a significant regulatory role in a wide range of physiological processes. To date, no genome-wide survey and expression analysis of this gene family in sugarcane has been performed. In this study we identified the nsLTP gene family in and carried out expression profiling of in two sugarcane cultivars ( spp.

Indirect Application of Intense Pulsed Light Induces Therapeutic Effects on Experimental Murine Meibomian Gland Dysfunction.

Purpose: To investigate the indirect effects of intense pulsed light (IPL) on morphological and pathological changes of the meibomian glands (MGs) in apolipoprotein E knockout ( ) mice and explore the underlying mechanisms.

Methods: mice were treated with or without IPL three times below the lower eyelids and MGs were not directly exposed to irradiation. The eyelids and ocular surface were observed under a stereoscope.

The Role of Neutrophil Extracellular Traps in the Ocular System.

Neutrophils remain at the top of congenital and adaptive immune systems. The past 20 years witnessed a steep rise in the interest in neutrophil extracellular traps (NETs), which are a novel type of anti-pathogen mechanism coordinated with neutrophils. However, accumulating data revealed that excessive NETs in the host were associated with exacerbated inflammation, thrombosis, and autoimmunity.

Comments on "Persistent, bioaccumulative, and toxic chemicals in insects: Current state of research and where to from here?".

A recent study published in Science of the Total Environment conducted a systematic review of persistent, bioaccumulative, and toxic chemicals (PBTs) in insects using Web of Science Core Collection. Interestingly, a remarkable increase of human, animal, and vertebrate publications related to PBTs appeared in the early 1990s. Despite the authors' attempts to illustrate the anomalies from different perspectives, no rational explanation has been found yet.

Characterization of T cell immunity in chronic hepatitis B virus-infected mothers with postpartum alanine transaminase flare.

Background: Postpartum alanine transaminase (ALT) flares occur frequently in chronic hepatitis B virus (HBV)-infected mothers with antepartum antiviral therapy (AVT). We aimed to characterize the T cell immunity in HBV-infected mothers experiencing postpartum ALT flares.

Methods: Twenty HBV-infected pregnant women who received AVT at 26-28 weeks of gestation were enrolled and followed up until 15-18 weeks postpartum.