Does Arthrocentesis Reduce Pain in Patients With Systemic Polyarthritis and Temporomandibular Joint Intra-Articular Pain and Dysfunction?

Background: Arthrocentesis is effective at reducing pain and improving function in patients with temporomandibular joint intra-articular pain and dysfunction (IPD). It remains unclear if it is equally effective in patients with systemic polyarthritis (SPA) and IPD.

Purpose: The purpose of this study was to compare changes in pain and function following arthrocentesis for IPD in subjects with and without SPA.

Is botulinum toxin the future of orofacial pain management? Evidence and perspectives.

Botulinum toxin (BTX) demonstrates potential as a complementary therapy in managing chronic orofacial pain (OFP), but challenges in the standardization of protocols and indications remain.

The development and pilot testing of the OroFacial Awakening Symptoms Questionnaire (OFASQ).

Background: The evolution of concepts that have featured the last decade in the field of bruxism led to the necessity of providing clinicians and researchers with adequate tools for the assessment of bruxism, such as the Standardized Tool for the Assessment of Bruxism (STAB) and the BruxScreen. The former is a multidimensional evaluation tool for the evaluation of bruxism status, while the latter is an instrument that could potentially find its applicability in large-scale epidemiological research projects for screening purposes. However, both tools lack the evaluation of orofacial symptoms at awakening, which can be predictive of temporomandibular disorders (TMDs) pain intensity and prognosis.

Pseudogout of the temporomandibular joint: a case report with systematic literature review.

Background: Calcium pyrophosphate dihydrate deposition disease (CPPD) is a metabolic disease resulting in acute arthritis. CPPD often affects joints containing fibrocartilage. The purpose of this review is to examine the clinical presentations, prevalence, and treatment modalities associated with CPPD when it affects the temporomandibular joint (TMJ).

Sleep bruxism and GERD correlation in a general population convenience sample.

Objective: To investigate the relationship between sleep bruxism(SB) and gastroesophageal reflux disease (GERD) with the use of validated questionnaires in a general population convenience sample.

Methods: SB behaviour was evaluated in accordance with the Subject-Based Assessment strategy recommended in the Standardized Tool for the Assessment of Bruxism (STAB). .

Standardised Tool for the Assessment of Bruxism: Translation, Cultural Adaptation and Pilot Testing in Italy.

Background: Recently, the Standardised Tool for the Assessment of Bruxism (STAB) has been developed for use in clinical and research settings.

Objectives: The aim of the present study is to describe the process of forward and back translation and pilot testing of the STAB into Italian.

Methods: The English version of the STAB was adopted as a template for translation into other languages, according to a step-by-step procedure led by the expert STAB bruxism panel and mother tongue experts in the field.

Temporomandibular disorders: INfORM/IADR key points for good clinical practice based on standard of care.

Objective: To present a list of key points for good Temporomandibular Disorders (TMDs) clinical practice on behalf of the International Network for Orofacial Pain and Related Disorders Methodology (INfORM) group of the International Association for Dental, Oral and Craniofacial Research (IADR).

Methods: An open working group discussion was held at the IADR General Session in New Orleans (March 2024), where members of the INfORM group finalized the proposal of a list of 10 key points.

Results: The key points covered knowledge on the etiology, diagnosis, and treatment.

Treatment of Condylar Hypoplasia in Alagille Syndrome - A Case Report.

Rationale: Alagille syndrome is a rare genetic disorder with dental and facial abnormalities in the head-and-neck area. It is autosomal dominant and occurs in approximately 1 in 100,000 people. No cases of Alagille Syndrome (ALGS) with mandibular hypoplasia and temporomandibular joint ankyloses (TMJa) have been reported to date.

Correlation between bilateral TMJ MRI findings: A systematic review of the literature.

The correlation between magnetic resonance imaging (MRI) signs and clinical findings has been highlighted in multiple studies. However, very little information is available on the correlation between the bilateral temporomandibular joints (TMJs) of the same individual. The majority of efforts in the clinical research setting have focused on the correlation between ipsilateral imaging and clinical findings, while less attention has been paid to the contralateral imaging findings of the anatomical structures.

Baseline masticatory muscles' performance may predict pain relief in temporomandibular disorders.

Objectives: To compare masticatory muscles' recruitment in patients with temporomandibular disorders and asymptomatic control subjects. To evaluate if the masticatory muscles' recruitment pattern may predict symptoms' improvement after temporomandibular disorders treatment.

Materials And Methods: Standardized surface electromyography of anterior temporalis and superficial masseters muscles were recorded and compared at baseline in 26 patients with arthrogenous temporomandibular disorders (study group) and 26 asymptomatic subjects (control group).

Is Botulinum Toxin Effective in Treating Orofacial Neuropathic Pain Disorders? A Systematic Review.

Background: The aim of this paper is to provide a systematic review of the literature regarding the clinical use of botulinum toxin (BTX) to treat various orofacial neuropathic pain disorders (NP).

Methods: A comprehensive literature search was conducted using Medline, Web of Science, and the Cochrane Library databases. Only randomized clinical trials (RCT) published between 2003 and the end of June 2023, investigating the use of BTX to treat NP, were selected.

Pediatric temporomandibular joint ankylosis and arthritis: Forgotten complications of acute otitis media.

Objectives: Temporomandibular joint (TMJ) arthritis and ankylosis represent unusual but potential complications of ear suppuration, especially in children. We performed a review of the literature of pediatric otogenic TMJ arthritis and ankylosis, discussing their clinical and radiological features, their mechanism of infection spread, and the importance of a prompt diagnosis and treatment. We additionally describe a case of TMJ ankylosis following acute mastoiditis in a 4-year-old female patient.

Botulinum Toxin for Treating Temporomandibular Disorders: What is the Evidence?

Aims: To systematically review the scientific literature for evidence concerning the clinical use of botulinum toxin (BTX) for the management of various temporomandibular disorders (TMDs).

Methods: A comprehensive literature search was conducted in the Medline, Web of Science, and Cochrane Library databases to find randomized clinical trials (RCT) published between 2000 and the end of April 2021 investigating the use of BTX to treat TMDs. The selected articles were reviewed and tabulated according to the PICO (patients/problem/population, intervention, comparison, outcome) format.

Computer-assisted surgery with custom prostheses and human amniotic membrane in a patient with bilateral class IV TMJ reankylosis: a case report.

A gold-standard technique has yet to be found for the treatment of temporomandibular joint ankylosis (TMJa), particularly in patients with recurring ankylosis. A 58-year-old male patient, with a history of multiple TMJ surgeries and severe limitation of mouth opening (maximum interincisal distance [MID] was 10 mm). Computerised tomography (CT) imaging highlighted a bilateral type IV ankylosis.

Human amniotic membrane: an improvement in the treatment of Medication-related osteonecrosis of the jaw (MRONJ)? A case-control study.

The aim of this article is to report the results obtained by the use of HAM in surgical wound healing and the reduction of relapse in patients affected by Medication-related osteonecrosis of the jaw (MRONJ).The study involved patients with the diagnosis of MRONJ, surgically treated between October 2016 and April 2019, in a case-control setting. Enrolled patients were randomly divided into 2 groups.

Variations of salivary concentration of cytokines and chemokines in presence of oral squamous cell carcinoma. A case-crossover longitudinal prospective study.

Salivary biomarkers represent a promising diagnostic tool. Non-invasive and stress-free sampling results in objective parameters able to overcome the need of clinical expertise required for a correct interpretation of early oral squamous cell carcinoma (OSCC). The present study aims at evaluating potential variations in the salivary concentration of cytokines in presence of OSCC.

Prognostic Significance of Serine-Phosphorylated STAT3 Expression in pT1-T2 Oral Tongue Carcinoma.

Objectives: Phosphorylated (activated) STAT3 (pSTAT3) is a regulator of numerous genes that play an essential part in the onset, development and progression of cancer; it is involved in cell proliferation and preventing apoptosis, and in invasion, angiogenesis, and the evasion of immune surveillance. This study aimed mainly to investigate the potential prognostic role of pSTAT3 expression in oral tongue squamous cell carcinoma (SCC).

Methods: Phospho-ser727 STAT3 immunolabeling was correlated with prognostic parameters in 34 consecutive cases of pT1-T2 tongue SCCs undergoing primary surgery.

The role of angiogenin in pT1-T2 tongue carcinoma neo-angiogenesis and cell proliferation: an exploratory study.

Background: Angiogenin (ANG) is a member of the ribonuclease superfamily and of medical interest largely because it supports the growth of primary and metastatic malignancies. This study is the first to investigate the potential role of ANG in tongue carcinoma neo-angiogenesis and cancer cell proliferation.

Methods: Angiogenin expression (in carcinoma cells and endothelial intratumor vessel cells), CD105-assessed micro-vessel density (MVD), and MIB-1 expression were correlated with prognostic parameters in 28 primarily consecutively operated pT1-T2 tongue carcinomas (squamous cell carcinoma [SCC]).