Adolescent pregnancy in French Guiana: double trouble for young mothers and small vulnerable newborns.

Objectives: Adolescent pregnancies (AP), defined as pregnancies in girls aged 10-19 years, are associated with adverse maternal and neonatal outcomes. They are frequently reported among those with low economic status. French Guiana (FG) is a French overseas territory with important social inequalities in South America, marked by inequalities.

Association of Asthma with Acute Vaso-Occlusive Crisis Among French Guianese Children with Sickle Cell Disease.

Objectives: To evaluate the impact of asthma on hospitalizations for acute vaso-occlusive pain episodes in children with sickle cell disease (SCD).

Methods: A multicenter nested case-control study was conducted over a period from January 1, 2012, to December 31, 2022.

Results: The mean age of the study population was 8.

Prevalence of lead poisoning among artisanal gold miners in French Guiana in 2022: a multicenter cross-sectional observational survey.

Background: Lead poisoning is a significant public health issue globally. In French Guiana, a French overseas territory in South America, several studies have reported widespread lead exposure in the local population. However, the associated risk factors remain insufficiently understood.

Disseminated Histoplasmosis in Persons Living with HIV, France and Overseas Territories,1992-2021.

Disseminated histoplasmosis is a major issue among persons with advanced HIV in the Americas; it might also affect persons in sub-Saharan Africa, the Caribbean, and Asia and can be mistaken for other infections. By using 1992-2021 data from the French hospital database on HIV, we analyzed 198,798 persons with HIV follow-up in France and its overseas territories, identifying 553 (2.8/1,000 person-years) first episodes of disseminated histoplasmosis.

Similar Microsatellite Allelic Distribution Between Population Collected by Human Landing Catch or Mosquito Magnet Traps in French Guiana.

is a major malaria vector in South America. Understanding its population dynamics is critical for designing effective vector control strategies. While various collection methods exist, they may sample distinct populations.

Use and health effects of herbal medicine Ocotea guianensis during pregnancy in French Guiana.

Ethnopharmacological Relevance: Ocotea guianensis Aubl. leaves, in Creole fey darjan ("silver leaves") are frequently cited by women in French Guiana for childbirth related practices. Although this use has been described in several ethnographic studies, the frequency of use of this plant has not been quantified yet.

Sexual Health Determinants During the Life Course and Migration of Haitian-Origin People in French Guiana: Protocol for the Parcours d'Haïti Biographical and Transdisciplinary Study.

Background: French Guiana, an overseas territory located in the Guiana Shield in South America, faces unique social and demographic challenges, particularly in relation to migration. Haitians represent 1 of the 3 largest foreign communities in the region and face specific barriers to health care access and prevention. They are also a population exposed to HIV infection.

Can diabetic peripheral neuropathy predict lacunar stroke in patients with diabetes?

Stroke is the leading-cause of death in women and motor-disability in adults. In patients with diabetes, diabetic peripheral neuropathy (DPN) increases the risk of ischemic stroke. The aim of this work was to test the hypothesis that an etiological pattern of ischemic stroke in patients with DPN can be recognized.

Evaluating the impact of the Malakit intervention on malaria transmission in the Guiana Shield: a mathematical modelling study.

Background: Malaria elimination in mobile and hard-to-reach populations calls for novel, tailored interventions. In French Guiana, the malaria burden is high among the population working in illegal gold mining. Between April 2018 and March 2020, we implemented , a new intervention targeting gold miners, and relying on the distribution of kits for the self-diagnosis and self-treatment of malaria.

High Genetic Diversity of Histoplasma in the Amazon Basin, 2006-2017.

Histoplasmosis is one of the most common pulmonary mycosis diseases in the world. Genome sequencing has revealed that Histoplasma, the cause of histoplasmosis, is composed of several phylogenetic species. The genetic diversity of the pathogen remains largely unknown, especially in the tropics.

Prevalence and risk factors of food insecurity during pregnancy: a multicenter survey in French Guiana.

Background: The post-COVID international situation, wars and food price inflation are hampering access to food for the most vulnerable households who have no safety net against unforeseen events. While pregnant women are particularly vulnerable to food shortages and nutritional imbalances, data on food insecurity during pregnancy and associated risk factors are scarce.

Methods: A 2023 multicenter, cross-sectional study was conducted among a representative sample of 730 women during the third trimester of pregnancy in French Guiana.

Acute hepatitis E virus infection in adults, Cayenne, French Guiana, 2015-2022.

Objectives: French Guiana (FG), a French overseas territory located in the Amazon region, is characterized by a high level of precariousness, which may be conducive to hepatitis E virus (HEV) transmission, but no recent relevant data exist.

Patients And Methods: We conducted a retrospective study to determine the incidence of acute HEV infection diagnosed at Cayenne Hospital, FG between 2015 and 2022.

Results: Among 934 tested individuals, 12 had positive anti-HEV IgM (positivity rate of 1.

A cross-sectional study assessing mercury exposure and poisoning among workers in informal gold mines in French Guiana.

Objectives: Informal gold mining represents a major source of mercury pollution worldwide. People involved in informal gold mining in French Guiana are mainly migrants from Brazil and represent an exposed, mobile and hard-to-reach population. This study assessed mercury poisoning in this particular population.

Methods, practices, and complications related to the use of artificial penile nodules within the French Guiana penitentiary.

Background: Artificial penile nodules (APNs) are small, handmade objects inserted under the penile skin, a practice deeply rooted in the prison environment of French Guiana, raising significant concerns related to sexual health, including complications and an increased risk of sexually transmitted infections (STIs).

Aim: The primary objective of the current study was to investigate APN practices, methods, and complications in prison and to identify risk factors for complications among APN users and their sexual partners.

Methods: This cross-sectional study was conducted among adult male detainees in June 2023 at the French Guiana Penitentiary (FGP).

High genetic diversity of in the Amazon basin, 2006-2017.

Genome sequencing has revealed that , the etiological agent of histoplasmosis is composed of several phylogenetic species. Nonetheless, the genetic diversity of the pathogen remains largely unknown, especially in the tropics. We sequenced the genome for 91 isolates from the Amazon basin, and used phylogenomics, and population genetic evidence to measure the genetic variation of the genus in South America.

Precariousness Represents an Independent Risk Factor for Depression in Children With Sickle Cell Disease.

While the prevalence and impact of depression have been widely described in sickle cell disease, its relationship with precariousness has never been studied. This study aimed to describe the prevalence of depression and its relationship with clinical and demographic factors including social precariousness in children with sickle cell disease in French Guiana. We included children aged 12-18 years with sickle cell disease from the Sickle Cell Reference Center in French Guiana.

Preeclampsia risk factors in French Guiana: a great heterogeneity among populations and geographic areas.

Background: French Guiana is France's largest overseas territory, accounting for 1/6th of mainland France. French Guiana has the highest fertility rate in France and Latin America. However, infant mortality, especially neonatal mortality, remains 2.

[Exposome and prostate cancer: Experience in a remote hospital in French Guiana].

Introduction: West Guiana is characterized by a precarious, poor, dispersed population, exposed to infectious and chemical factors. Prostate cancer is the leading cancer in terms of incidence in men. We examined its characteristics, management and main exposomes in this context.

[Fatal case of co-infection with yellow fever virus and SARS-CoV2 during the 2020 Covid-19 pandemic in French Guiana].

The yellow fever virus (YFV), recently renamed is an arbovirus of the Flaviviridae family and genus endemic in South America and Tropical Africa. Brazil experienced an epidemic of unprecedented magnitude between 2016 and 2018. The resurgence of new cases in French Guiana in recent years has rekindled interest in the disease.

Asthma Is an Independent Risk Factor for Acute Chest Syndrome in Children with Sickle Cell Disease in French Guiana.

The overall incidence of asthma in children with sickle cell disease in French Guiana is unknown. Asthma is common in children with sickle cell disease and is associated with increased morbidity and mortality. This study aimed to describe the impact of asthma on the occurrence of acute chest syndrome in children with sickle cell disease who were followed up in French Guiana.

[Implementation of geriatric oncology in a remote hospital in French Guiana].

Introduction: The aim was to analyze the implementation of the Onco-Geriatrics model in a remote ultramarine territory: West-French Guiana. The population is socially precarious in terms of income, social coverage and administrative status, and most often speaks a non-French language and has a non-Western culture.

Methods: Narrative description of the implementation and retrospective study of anonymized data from the database of older patients managed for cancer between September 2014 and December 2020.