Does high compliance with the enhanced recovery after surgery protocol improve 5-year survival? A cohort study of 468 nonmetastatic colorectal cancer patients.

Introduction: Well‑documented immediate benefits of the enhanced recovery after surgery (ERAS) protocol highlight the need to explore its long‑term impact, particularly on survival outcomes in colorectal cancer.

Objectives: The aim of this study was to analyze the impact of the ERAS protocol compliance on the long‑term outcomes after laparoscopic colorectal resection.

Patients And Methods: Data from 468 patients who underwent laparoscopic colorectal resection between 2013 and 2017 were prospectively collected.

Changes in Circulating Adipokine Levels in COVID-19 Patients.

: The COVID-19 pandemic has posed significant global health challenges. Despite extensive research efforts, the inflammatory response triggered by SARS-CoV-2 remains to be further explored and understood. Our study aims to examine the changes in serum concentrations of pro-inflammatory adipokines-visfatin and leptin-in COVID-19 patients in relation to a healthy control group.

Identification of miRNAs Present in Cell- and Plasma-Derived Extracellular Vesicles-Possible Biomarkers of Colorectal Cancer.

Globally, an increasing prevalence of colorectal cancer (CRC) prompts a need for the development of new methods for early tumor detection. MicroRNAs (also referred to as miRNAs) are short non-coding RNA molecules that play a pivotal role in the regulation of gene expression. MiRNAs are effectively transferred to extracellular vesicle (EVs) membrane sacs commonly released by cells.

Low-profile versus standard-profile stent grafts in the treatment of abdominal aortic aneurysm: a case-matched study.

Introduction: Endovascular aortic repair (EVAR) is nowadays a widespread method of managing abdominal aortic aneurysm (AAA). Low-profile stent grafts (LPSGs) enable treatment of patients with complex and anatomically challenging aneurysms, and facilitate a percutaneous and thus less invasive procedure.

Aim: To assess the outcomes of EVAR with low-profile versus standard-profile stent grafts (SPSGs).

A longer pelvis is associated with longer operative time in transanal total mesorectal excision (TME) but not in laparoscopic TME. Results from a retrospective cohort study.

Introduction: A narrow pelvis, obesity, and bulky low rectal tumor are perceived as risk factors for intraoperative difficulties during total mesorectal excision (TME), particularly in the laparoscopic approach. A transanal approach has been developed to overcome the difficulties encountered during laparoscopic TME. There is no clear definition of a narrow pelvis that would guide preoperative surgical planning.

Visual Impairment in Hemodialyzed Patients-An IVIS Study.

: The growing and aging population of hemodialysis patients has become increasingly disabled, with more complex comorbidities, and are older upon initiating dialysis. Visual impairment can adversely affect their quality of life and life satisfaction. Treatment evaluation should not only consider remission of the disease, but also the improvement of quality of life and life satisfaction.

Modified Frailty Index and Brief Geriatric Assessment does not predict prolonged hospitalization in elderly patients undergoing appendectomy due to Acute Appendicitis.

Introduction: Epidemiology and the outcomes of acute appendicitis in elderly people are very different from the younger patients. Aim of this study was to investigate the significance of frailty syndrome in the course of acute appendicitis.

Methods: All patients over 65 years old who underwent laparoscopic appendectomy between 2013 and 2021 in 2nd Department of General Surgery were included in the study.

Radiological Features for Frailty Assessment in Patients Requiring Emergency Laparotomy.

Introduction: As the number of elderly patients requiring surgical intervention rises, it is believed that frailty syndrome has a greater impact on perioperative course than on chronological age. The aim of this study was to evaluate the efficacy of various imaging features for frailty assessment in patients undergoing emergency laparotomy.

Methods: The study included all patients that qualified for emergency surgery with preoperative CT scans between 2016 and 2020 in the Second Department of General Surgery.

Mo-MDSCs are pivotal players in colorectal cancer and may be associated with tumor recurrence after surgery.

Colorectal cancer (CRC) is the third most common malignancy. Its development and progression is associated with natural immunosuppression related, among others, to myeloid derived suppressor cells (MDSCs). Overall, 54 patients in different stage of CRC, before any treatment were recruited into the study.

Quality of Life After Bariatric Surgery-a Systematic Review with Bayesian Network Meta-analysis.

Objective: Comprehensive analysis and comparison of HRQoL following different bariatric interventions through systematic review with network meta-analysis.

Background: Different types of bariatric surgeries have been developed throughout the years. Apart from weight loss and comorbidities remission, improvement of health-related quality of life (HRQoL) is an important outcome of metabolic surgery.

Immunonutrition Changes Inflammatory Response in Colorectal Cancer: Results from a Pilot Randomized Clinical Trial.

Introduction: Surgery is the first choice of treatment for colorectal cancer. Nutritional support in the form of oral nutritional supplements (ONSs) in the preoperative period is widely accepted for reducing the incidence of perioperative complications, and immunonutrition is generally recommended. However, there is little clinical data regarding the impact of such treatment on tumor biology.

Laparoscopic Sleeve Gastrectomy with Omentopexy: Is It Really a Promising Method?-A Systematic Review with Meta-analysis.

Purpose: Laparoscopic sleeve gastrectomy (LSG) is one of the most commonly performed bariatric procedure worldwide. Omentopexy during LSG is a novel variation of this well-established technique. There are no clear conclusions on indications for this procedure, safeness, and effects of such a method.

High compliance to ERAS protocol does not improve overall survival in patients treated for resectable advanced gastric cancer.

Introduction: The ERAS (Enhanced Recovery after Surgery) protocol revolutionized perioperative care for gastrointestinal surgical procedures. However, little is known about the association between adherence to the ERAS protocol in gastric cancer surgery and the oncological outcome.

Aim: To explore the relation between adherence to the ERAS protocol and the oncological outcome in gastric cancer patients.

Gender as a predictive factor in cholecystectomy - is it true or false?

Introduction: Cholecystolithiasis is one of the most frequent disorders of the human digestive system in a present population. It is common to point out that male gender is one of strong risk factors for complications during cholecystectomy, however the debate about that seems to be still open.

Aim Of The Study: The aim of this study was to compare the values related to the course and treatment effects between gender in patients undergoing cholecystectomy, based on own material.

Return to play after brain tumor surgery in children.

Purpose: Children with a history of brain tumors do not appear to be at a significantly higher risk of sports-related injuries. Nevertheless, according to the systematic review and survey conducted by Perreault et al., 75% of healthcare professionals restrict their patients' participation in physical activities after brain tumor surgery.

Laparoscopic versus open liver resections of posterolateral liver segments - a systematic review and meta-analysis.

Introduction: Laparoscopic resection has become an accepted approach to liver tumour surgery. However, it is considered difficult, especially in unfavourably located lesions.

Aim: To compare the outcomes of laparoscopic (LLR) and open liver resection (OLR) of posterolateral segments.

"Analysis of readmissions to the emergency department among patients presenting with abdominal pain".

Background: Abdominal pain is one of the most common complaints among patients admitted to the Emergency Department (ED). Diagnosis and management of abdominal pain may be a challenge and there are patients who require admission to the ED more than once in a short period of time. Our purpose was to assess the incidence of readmissions among patients treated in the ED due to abdominal pain and to investigate the impact of readmission on the further course of treatment.

A systematic review and meta-analysis of laparoscopic versus robotic rectal surgery with primary anastomosis.

Purpose: Rectal cancer is one of the most common malignancies of the gastrointestinal tract. The gold standard method is surgical resection. The approach to rectal cancer is still controversial.

Feasibility of modified Edmonton Obesity Staging System in bariatric center.

Background: The number of bariatric procedures is growing worldwide annually. While there is no doubt that a high body mass index is fundamental in qualification for surgical intervention, the Edmonton Obesity Staging System (EOSS) developed in 2009 may be an additional tool for identifying patients for whom surgery should be performed and those for whom the surgery should be postponed.

Objective: Assessment of the feasibility of modified EOSS as a qualification tool for surgery for obesity and related diseases and its association with morbidity.

Evaluation of the learning curve of transanal total mesorectal excision: single-centre experience.

Introduction: Transanal total mesorectal excision (TaTME) has been recently proposed to overcome the difficulties of the standard TME approach, allowing better visualization and dissection of the mesorectal fascia. Although TaTME seems very promising, the evidence and body of knowledge on achieving proficiency in performing it are still sparse.

Aim: To evaluate the learning curve of TaTME based on a single centre's experience.

Challenges associated with bariatric surgery - a multi-center report.

Introduction: Due to the constantly growing demand for surgical treatment of obesity, it is necessary to create new bariatric centers and further improve presently active ones.

Aim: To identify which stages of conducting peri-operative care and organizing a modern bariatric center currently pose the greatest challenge.

Material And Methods: An anonymous survey was designed and distributed to bariatric surgeons.

Perioperative changes in lymphocyte subpopulations in patients undergoing surgery for colorectal cancer.

Surgical procedure has immense impact on the immune balance. However, little is known about perioperative changes in T regulatory and Th17 lymphocyte subpopulations in patients undergoing colorectal resection. Patients with resectable colon cancer were enrolled in the study.

Author Correction: Risk factors for serious morbidity, prolonged length of stay and hospital readmission after laparoscopic appendectomy - results from Pol-LA (Polish Laparoscopic Appendectomy) multicenter large cohort study.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.