Publications by authors named "Marissa A DiPiero"
Inhibitory control (IC) develops in stages from infancy through adolescence and is associated with numerous developmental disorders and learning outcomes. This study examined how neural architecture - in particular myelination - underlies brain activation patterns observed during IC tasks in a sample of 28 children aged 4-10 years old. IC was observed using reaction times during go/no-go and flanker IC tasks.
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- The early stages of brain development from fetus to infancy are crucial for growth and can influence future neurodevelopmental and psychiatric disorders.
- Research into the microstructure of gray matter during this period is important for understanding potential challenges in intelligence and behavior later in life.
- This study employs a refined imaging technique, NODDI GBSS, to analyze and improve the understanding of gray matter development in infants within their first month, uncovering significant relationships in its architecture.
Background: Autism spectrum disorder (ASD) is a complex neurodevelopmental condition. Understanding the brain's microstructure and its relationship to clinical characteristics is important to advance our understanding of the neural supports underlying ASD. In the current work, we implemented Gray-Matter Based Spatial Statistics (GBSS) to examine and characterize cortical microstructure and assess differences between typically developing (TD) and autistic males.
View Article and Find Full Text PDFDifferential Maturation of Auditory Cortex Activity in Young Children with Autism and Typical Development.
J Autism Dev Disord
October 2023
Maturation of auditory cortex neural encoding processes was assessed in children with typical development (TD) and autism. Children 6-9 years old were enrolled at Time 1 (T1), with follow-up data obtained ~ 18 months later at Time 2 (T2), and ~ 36 months later at Time 3 (T3). Findings suggested an initial period of rapid auditory cortex maturation in autism, earlier than TD (prior to and surrounding the T1 exam), followed by a period of faster maturation in TD than autism (T1-T3).
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- The study focused on identifying functional brain markers, specifically in the auditory cortex, to aid pediatric clinical research on brain abnormalities.
- Researchers measured auditory evoked fields using magnetoencephalography (MEG) in 15 typically developing children aged 6-8, conducting tests at three different times over three years.
- Results showed consistent M50 responses across time but highlighted variability in latency changes among individual children, indicating potential challenges in establishing reliable markers for clinical use.
Studies suggest that individuals with autism spectrum disorder (ASD) exhibit altered electrophysiological alpha to gamma phase-amplitude coupling (PAC). Preliminary reports with small samples report conflicting findings regarding the directionality of the alpha to gamma PAC alterations in ASD. The present study examined resting-state activity throughout the brain in a relatively large sample of 119 children with ASD and 47 typically developing children.
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