Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Maturation of auditory cortex neural encoding processes was assessed in children with typical development (TD) and autism. Children 6-9 years old were enrolled at Time 1 (T1), with follow-up data obtained ~ 18 months later at Time 2 (T2), and ~ 36 months later at Time 3 (T3). Findings suggested an initial period of rapid auditory cortex maturation in autism, earlier than TD (prior to and surrounding the T1 exam), followed by a period of faster maturation in TD than autism (T1-T3). As a result of group maturation differences, post-stimulus group differences were observed at T1 but not T3. In contrast, stronger pre-stimulus activity in autism than TD was found at all time points, indicating this brain measure is stable across time.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372967PMC
http://dx.doi.org/10.1007/s10803-022-05696-8DOI Listing

Publication Analysis

Top Keywords

auditory cortex
12
maturation auditory
8
typical development
8
maturation autism
8
autism
5
time
5
differential maturation
4
cortex activity
4
activity young
4
young children
4

Similar Publications

Alpha oscillations have been implicated in the maintenance of working memory representations. Notably, when memorised content is spatially lateralised, the power of posterior alpha activity exhibits corresponding lateralisation during the retention interval, consistent with the retinotopic organisation of the visual cortex. Beyond power, alpha frequency has also been linked to memory performan ce, with faster alpha rhythms associated with enhanced retention.

View Article and Find Full Text PDF

The human auditory system must distinguish relevant sounds from noise. Severe hearing loss can be treated with cochlear implants (CIs), but how the brain adapts to electrical hearing remains unclear. This study examined adaptation to unilateral CI use in the first and seventh months after CI activation using speech comprehension measures and electroencephalography recordings, both during passive listening and an active spatial listening task.

View Article and Find Full Text PDF

Objective: To investigate the characteristics of brain structures in patients with noise-induced hearing loss (NIHL) using source-based morphometry (SBM) and to evaluate the correlation between abnormal brain regions and clinical data.

Methods: High-resolution 3D T1 structural images were acquired from 81 patients with NIHL and 74 age- and education level-matched healthy controls (HCs). The clinical data of all subjects were collected, including noise exposure time, monaural hearing threshold weighted values (MTWVs), Mini-Mental State Examination (MMSE), and Hamilton Anxiety Scale (HAMA) scores.

View Article and Find Full Text PDF

Distinct Neural Mechanisms of Visual and Sound Adaptation in the Cat Visual Cortex.

Eur J Neurosci

September 2025

The Tampa Human Neurophysiology Lab, Department of Neurosurgery, Brain and Spine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.

Sensory areas exhibit modular selectivity to stimuli, but they can also respond to features outside of their basic modality. Several studies have shown cross-modal plastic modifications between visual and auditory cortices; however, the exact mechanisms of these modifications are yet not completely known. To this aim, we investigated the effect of 12 min of visual versus sound adaptation (referring to forceful application of an optimal/nonoptimal stimulus to a neuron[s] under observation) on the infragranular and supragranular primary visual neurons (V1) of the cat (Felis catus).

View Article and Find Full Text PDF

A clinical and genotype-phenotype analysis of MACF1 variants.

Am J Hum Genet

September 2025

Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, PO Box 2040, Rotterdam 3000 CA, the Netherlands.

Microtubule-actin cross-linking factor 1 (MACF1) is a large protein of the spectraplakin family, which is essential for brain development. MACF1 interacts with microtubules through the growth arrest-specific 2 (Gas2)-related (GAR) domain. Heterozygous MACF1 missense variants affecting the zinc-binding residues in this domain result in a distinctive cortical and brain stem malformation.

View Article and Find Full Text PDF