Publications by authors named "Marina Gabriela Birck"
Associations of TSH, free T3, free T4, and conversion ratio with incident hypertension: results from the prospective Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).
Arch Endocrinol Metab
May 2024
Objective: To evaluate the association of TSH, free T3 (FT3), free T4 (FT4), and conversion (FT3:FT4) ratio values with incident hypertension.
Materials And Methods: The study included data from participants of the ELSA-Brasil study without baseline hypertension. Serum TSH, FT4 and FT3 levels, and FT3:FT4 ratio values were assessed at baseline, and incident hypertension (defined by blood pressure levels ≥ 140/90 mmHg) was estimated over a median of 8.
Potential Determinants of Thyroid Peroxidase Antibodies and Mortality Risk: Results From the ELSA-Brasil Study.
J Clin Endocrinol Metab
January 2024
Article Synopsis
- The study explored the link between thyroid peroxidase antibodies (TPOAbs) and mortality, examining how sociodemographic and lifestyle factors influence TPOAb levels.
- Younger age, higher body mass index, female sex, and smoking habits were identified as key determinants of detectable and positive TPOAb levels among participants.
- Higher TPOAb levels were associated with increased cancer-related mortality risk in men and other causes of mortality in women, although the overall low mortality rate in the sample suggests a need for more research into the clinical significance of TPOAbs.
Maintained activity in ankylosing spondylitis patients treated with TNFi and/or NSAID for at least 12 weeks: a cross-sectional study in Brazil.
Adv Rheumatol
October 2022
Background: The aim of this study was to evaluate disease activity among patients with axial spondyloarthritis (AS) treated with tumor necrosis factor inhibitors (TNFi) and/or nonsteroidal anti-inflammatory drugs (NSAIDs) for at least 12 weeks in private outpatient settings in Brazil.
Methods: This was a cross-sectional, real-world study conducted in 17 Brazilian private health care institutes. Patients were selected if diagnosed with AS or axial radiographic spondyloarthritis (AxSpA) and treated with NSAIDs or TNFi for at least 12 weeks within the last 26 weeks prior to enrollment.
Objectives: To explore asthma control in patients undergoing pharmacotherapy on studies in the last 20 years in Brazil. Asthma is a chronic airway inflammation disease with a high prevalence worldwide. Even with a variety of drug treatment improvements, attaining asthma control is challenging, since it should have a personalized approach.
View Article and Find Full Text PDFThyroid-Stimulating Hormone and Thyroid Hormones and Incidence of Diabetes: Prospective Results of the Brazilian Longitudinal Study of Adult Health (ELSA-BRASIL).
Thyroid
June 2022
There are conflicting data regarding the association of thyroid function with incident diabetes. We prospectively investigated thyrotropin (TSH), free thyroxine (fT4), free triiodothyronine (fT3), and its conversion ratio (fT3:fT4) with the risk of developing diabetes in euthyroid subjects and those with subclinical thyroid dysfunction. Our hypothesis is that this relationship is a U-shaped curve since both subclinical thyroid diseases may be associated with diabetes.
View Article and Find Full Text PDFBackground: Age-related macular degeneration (AMD) is a disease that causes damage in the macular region of the retina, leading to irreversible blindness. This study aims to understand the profile and care of patients with AMD and its cost at the Brazilian public health system to identify AMD-care needs.
Methods: This is a retrospective observational study of AMD with real-world data from the Brazilian public healthcare system, using DATASUS claim databases.
Article Synopsis
- Coronary heart disease (CHD) is a leading cause of death globally, including Brazil, and standard medications can lower the risk of further events and mortality after an initial incident.
- * The study analyzed secondary prevention efforts for CHD in Brazil, focusing on how these efforts relate to various participant demographics in the ELSA-Brasil data.
- * Results showed that only about 35% of participants used recommended medications post-CHD, with lower usage rates in women and those from low-income backgrounds, despite similarities in use across different time periods since the heart event.*
Background: Secondary prevention of stroke is a very important goal for achieving continuous reduction in stroke mortality rates over the next decades.
Design And Setting: Cross-sectional analysis on the Brazilian Longitudinal Study of Adult Health -(ELSA-Brasil), with data from Salvador, Vitória, Belo Horizonte, Rio de Janeiro, São Paulo and Porto Alegre.
Methods: This descriptive analysis focused on secondary prevention of stroke among participants who self-reported a medical diagnosis of stroke at the baseline of ELSA-Brasil, and its association with sociodemographic characteristics.