Publications by authors named "Isabela Martins Bensenor"

The aim of this study was to describe dietary patterns using three diet quality indices and the associated factors among 15,081 participants from the baseline of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Dietary intake was assessed through a food frequency questionnaire. Three diet quality indices were applied: the Planetary Health Diet Index (PHDI), the Cardiovascular Health Diet Index (CHDI), and the Healthy Eating Index-2015 (HEI-2015).

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Background: Due to enhancements in health care, the number of individuals who survive an acute coronary syndrome (ACS) event is rising. In this population, the impact of physical activity on long-term survival is still a matter of debate. We aimed to analyze the association between the level of physical activity during the first 4 years of follow-up and survival.

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Background: While midlife obesity is linked to cognitive decline, this association is inconsistent in older adults, possibly due to the limitations of body mass index (BMI) in accurately assessing adiposity at older ages. Most studies focused on White or Asian populations, did not include other adiposity measures besides BMI, adjusted the analyses for mediators, and did not investigate potential subgroup-specific associations. We compared the associations of adiposity measured by anthropometrical and bioelectrical impedance analysis (BIA) with cognitive performance in a diverse population, examining modifications by age, sex, and race, and investigating the mediating effects of obesity-related comorbidities.

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Background And Aims: Elevated low-density lipoprotein-cholesterol (LDL-C) is a modifiable risk factor for dementia, but evidence on other lipids is inconsistent, particularly in studies from low and middle-income countries. This study aimed to assess the association between lipid levels and cognitive decline in the ELSA-Brasil cohort.

Methods: In this prospective study, baseline serum lipid profile [total cholesterol (TC), LDL-C, high-density lipoprotein-cholesterol (HDL-C), triglycerides, and non-high-density lipoprotein-cholesterol (Non-HDL-C)] was analyzed.

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The Cardiovascular Health Diet Index (CHDI) is a diet quality score based on the dietary guidelines of the American Heart Association for cardiovascular health but with some adaptations, such as red meat, dairy products, beans and ultra-processed foods in its components. The CHDI has shown good relative validity parameters; however, its association with health outcomes is still unclear. Thus, our aim was to investigate the association between the CHDI score with subclinical atherosclerosis.

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Article Synopsis
  • A group called the EAT-Lancet Commission created a healthy eating plan to help people and the planet, but it wasn't clear how it affects our thinking as we get older.
  • A study looked at over 11,700 people in Brazil and found that following this healthy eating plan helped slow down memory loss, especially for those with higher income.
  • Results showed that people with more money had a better chance of keeping their memory sharp, so it’s important to think about how income affects how well people can follow healthy diets.
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Objective: The aim of this study was to investigate whether sex, age, race, income, education, and marital status are associated with having a religion in a sample of Brazilian men and women.

Methods: Data were obtained from 15,098 participants of the Brazilian Longitudinal Study of Adult Health, a longitudinal study that ultimately aims to investigate long-term outcomes of chronic diseases. The sociodemographic characteristics and data on religion status were self-reported during interviews conducted by trained personnel.

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  • This study looked at how mental health issues relate to headaches like migraines and tension-type headaches in middle-aged adults in Brazil.
  • Most people in the study reported having headaches, with tension-type headaches being the most common.
  • It found that anxiety and other mental health symptoms were linked to migraines more than tension-type headaches, suggesting that feeling anxious can worsen headaches.
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Background/objectives: The association between dietary acid load (DAL) and chronic kidney disease (CKD) progression remains controversial. Also, there is a gap in the literature on the association between DAL and mortality. In this study, we evaluated the association between NEAP (net endogenous acid production) and PRAL (potential renal acid load) and the risk of events of all-cause mortality and kidney replacement therapy (KRT) in people with CKD.

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  • The study explored the link between thyroid peroxidase antibodies (TPOAbs) and mortality, examining how sociodemographic and lifestyle factors influence TPOAb levels.
  • Younger age, higher body mass index, female sex, and smoking habits were identified as key determinants of detectable and positive TPOAb levels among participants.
  • Higher TPOAb levels were associated with increased cancer-related mortality risk in men and other causes of mortality in women, although the overall low mortality rate in the sample suggests a need for more research into the clinical significance of TPOAbs.
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Objective: This study investigated the association of psoriasis with cardiovascular risk factors and psychological aspects among participants of the Brazilian Longitudinal Study of Adult Health.

Methods: This is a cross-sectional study from the baseline data of the Brazilian Longitudinal Study of Adult Health cohort, collected between 2008 and 2010 in six state capitals of Brazil (i.e.

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Purpose: We aimed to perform a cross-sectional evaluation of the association between dietary patterns and carotid intima-media thickness (cIMT), using baseline data from the Brazilian Longitudinal Study of Adult Health.

Methods: The participants with measurement of the cIMT were included (n = 9,624). cIMT was evaluated in a continuous way and categorized as < 75th and ≥ 75th and ≤ 0.

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Introduction: We aimed to investigate the association of frailty with persistent and incident common mental disorders (CMD) in older adults during the pandemic.

Methods: We included 706 older adults who participated in the onsite wave of the ELSA-Brasil study (2017-2019) and the online COVID-19 assessment (May-July 2020). CMD were assessed in both waves by the Clinical Interview Schedule-Revised.

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This study aimed to predict dietary recommendations and compare the performance of algorithms based on collaborative filtering for making predictions of personalized dietary recommendations. We analyzed the baseline cross-sectional data (2008-2010) of 12,667 participants of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). The participants were public employees of teaching and research institutions, aged 35-74 years, and 59% female.

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Purpose: The EAT-Lancet Commission released a reference sustainable diet to improve human health and respect the planetary boundaries. The Planetary Health Diet Index (PHDI) was developed with the purpose of evaluate the adherence to this reference diet. The aim of the present study was to evaluate the association between adherence to the EAT-Lancet diet with cardiometabolic risk profile.

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Background: Acute coronary syndrome (ACS) is one of the main manifestations of coronary artery disease, with a higher prevalence and worst prognosis. Oxidative stress is important in atherosclerosis and ACS, and paraoxonase 1 (PON1) is directly related to reducing the effects of oxidative stress on lipoproteins. The present study evaluated the prognostic value of PON1 activity in patients with non-ST-segment elevation ACS [non-ST-segment elevation myocardial infarction (NSTEMI) and unstable angina (UA)], included in the ERICO study.

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High salt intake has been linked to both obesity and high blood pressure (BP). Part of the variability of BP attributed to salt intake might be BMI-mediated. To investigate whether hypertension would be an effect modifier in the complex network including salt intake, obesity, and BP, we tested the hypothesis that salt intake has direct and BMI-mediated effects on systolic (SBP) and diastolic blood pressure (DBP).

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Background: Advances in technology have led to the identification of a greater number of metabolites related to diet. Although fruit intake biomarkers have been reported in some studies, these findings require further replication, considering the relevance of fruits for diet quality and health.

Objectives: The aim of this study was to explore the associations of a set of potential urinary biomarkers of diet, assessed using a targeted metabolomics approach, with self-reported fruit intake data in participants of a computer-assisted 24-h dietary recall (GloboDiet software) validation study.

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Article Synopsis
  • The American Heart Association (AHA) has introduced the "ideal cardiovascular health" (ICH) concept, which scores diet quality based on guidelines and the impact of ultra-processed foods on health.
  • Researchers proposed the Cardiovascular Health Diet Index (CHDI), based on a study of 14,779 participants in Brazil, which evaluates diet quality on a scale from 0 to 110 points.
  • The CHDI showed validity and reliability, revealing that smokers had significantly lower scores than non-smokers and was associated with higher overall dietary quality after adjusting for age and sex.
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  • - * The study explored how various data-driven methods can identify dietary patterns (DP) in the ELSA-Brasil population, focusing on the distinctions and similarities between these methods.
  • - * Three statistical techniques were utilized: factor analysis (FA), treelet transform (TT), and reduced rank regression (RRR), which all indicated certain common dietary patterns like the "convenience DP" and a "prudent DP".
  • - * Results showed a significant agreement between FA and TT for the prudent DP (75% agreement), while TT and RRR had lower agreement for the convenience DP (44.8%), emphasizing that each method has its unique strengths in capturing dietary complexity.
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Background: Machine learning investigates how computers can automatically learn. The present study aimed to predict dietary patterns and compare algorithm performance in making predictions of dietary patterns.

Methods: We analysed the data of public employees (n = 12,667) participating in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).

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Cohort studies have displayed mixed findings on changes in mental symptoms severity in 2020, when the COVID-19 pandemic outbreak started. Network approaches can provide additional insights by analyzing the connectivity of such symptoms. We assessed the network structure of mental symptoms in the Brazilian Longitudinal Study of Health (ELSA-Brasil) in 3 waves: 2008-2010, 2017-2019, and 2020, and hypothesized that the 2020 network would present connectivity changes.

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The EAT-Lancet Commission has proposed a model diet to improve the health of human beings and that of the planet. Recently, we proposed the Planetary Health Diet Index (PHDI) to assess adherence of the population to this model diet. In this study, we aimed to evaluate adherence to the PHDI and obesity outcomes using baseline data from 14,515 participants in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).

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The study aims to describe the consumption of alcoholic and non-alcoholic beverages according to sociodemographic, health and location variables. Cross-sectional study with ELSA-Brasil data (2008-2010). A questionnaire was used to collect sociodemographic, food, health data and anthropometry.

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The EAT-Lancet Commission has proposed a planetary health diet. We propose the development of the Planetary Health Diet Index (PHDI) based on this proposed reference diet. We used baseline dietary data obtained through a 114-item FFQ from 14,779 participants of the Longitudinal Study on Adult Health, a multicenter cohort study conducted in Brazil.

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