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Background: Due to enhancements in health care, the number of individuals who survive an acute coronary syndrome (ACS) event is rising. In this population, the impact of physical activity on long-term survival is still a matter of debate. We aimed to analyze the association between the level of physical activity during the first 4 years of follow-up and survival.
Methods: We analyzed data from 692 patients admitted due to an ACS event in a community hospital in Brazil. Physical activity was assessed using the long version of the International Physical Activity Questionnaire at 30 days, 180 days, and yearly after the first event. Mortality data were obtained using phone contacts, medical records, and official death documents. We built time-dependent Cox proportional hazard models to analyze whether physical activity levels during follow-up were associated with survival.
Results: Our main sample had 280 (40.5%) women and a mean age of 62.6 (12.5) years. In all assessments, 50.8% to 74.9% of study participants had physical activity levels below recommendations for healthy individuals. Physical inactivity increased the risk of death (hazard ratio [HR], 1.82; 95% confidence interval, 1.13-2.92). There was no statistically significant survival difference between insufficiently active and active participants.
Conclusions: Many individuals who survive an ACS event have poor physical activity levels. Physical inactivity after an ACS event significantly increases the risk of death. Our findings provide additional support to reinforce, in clinical practice, the benefits of physical activity in individuals who survive an ACS event.
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http://dx.doi.org/10.1123/jpah.2024-0138 | DOI Listing |
Diabetes
September 2025
Institute for Physical Activity and Nutrition, Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Victoria, Australia.
Unlabelled: Despite stimulating glucagon secretion, the mechanisms by which protein ingestion lowers glucose excursions remain unclear. We investigated this using the triple stable isotope glucose tracer technique to measure postprandial glucose fluxes. Eleven healthy adults completed three trials, ingesting 25 g glucose (25G; 100 kcal), 50 g glucose (50G; 200 kcal), or 25 g glucose plus 25 g whey protein (25WG; 200 kcal).
View Article and Find Full Text PDFJAMA Psychiatry
September 2025
School of Psychological Sciences, Monash University, Melbourne, Victoria, Australia.
Importance: Cannabis is the most commonly used illicit drug, with 10% to 30% of regular users developing cannabis use disorder (CUD), a condition linked to altered hippocampal integrity. Evidence suggests high-intensity interval training (HIIT) enhances hippocampal structure and function, with this form of physical exercise potentially mitigating CUD-related cognitive and mental health impairments.
Objective: To determine the impact of a 12-week HIIT intervention on hippocampal integrity (ie, structure, connectivity, biochemistry) compared with 12 weeks of strength and resistance (SR) training in CUD.
Background: People with dementia who have a fall can experience both physical and psychological effects, often leading to diminished independence. Falls impose economic costs on the healthcare system. Despite elevated fall risks in dementia populations, evidence supporting effective home-based interventions remains limited.
View Article and Find Full Text PDFNeurochem Res
September 2025
Biology and Health Laboratory, Faculty of Sciences, Ibn Tofail University, Kenitra, Morocco.
Parkinson's disease (PD) is characterized by impairments in motor control following the degeneration of dopamine-producing neurons located in the substantia nigra pars compacta. Environmental pesticides such as Paraquat (PQ) and Maneb (MB) contribute to the onset of PD by inducing oxidative stress (OS). This study evaluated the therapeutic efficacy of moderate physical activity (PA) on both motor and non-motor symptoms in a Wistar rat model of Paraquat and Maneb (PQ/MB) induced PD.
View Article and Find Full Text PDFCommunity Ment Health J
September 2025
The University of Queensland, Herston, Australia.
Engaging residents with the support available at community-based residential mental health rehabilitation facilities is an ongoing challenge for health services. This study explored factors associated with residential rehabilitation engagement across Queensland, Australia through regression modelling of cross-sectional data from a statewide benchmarking activity completed in 2023 (n = 208). The Residential Rehabilitation Engagement Scale (RRES) assessed each resident's rehabilitation engagement.
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