Publications by authors named "Man She"
Relationship between dry eye and expressions of CXCR3 and CCR5 after ocular acid burn.
BMC Ophthalmol
December 2022
Objective: To investigate the manifestation of dry eye and its relationship with CXCR3 and CCR5 expression in patients with ocular acid burns.
Methods: This is a case-control study. A total of 27 eyes of 22 cases ocular with acid burns of I-V degrees from Jan.
Clinical Relevance: Orthokeratology (OK) lens is commonly used to control myopia progression of children. Understanding the relationship between relative peripheral refraction (RPR) and the growth rate of axial length (AL) may assist in explaining myopic progression.
Background: The aim of this work is to investigate the RPR in myopic children wearing OK lenses, and to evaluate its relationship with the growth rate of AL.
Previous studies have found that amphiregulin (AREG) may participate in eye elongation during the development of myopia, but the mechanism remains unclear. Here, we tested tear concentrations of AREG in adults and detected the role of AREG in scleral remodeling in form-deprivation myopia (FDM) in guinea pigs. We found the tear concentrations of AREG in myopes were significantly higher than those in emmetropes using enzyme-linked immunosorbent assay (ELISA).
View Article and Find Full Text PDFPurpose: To investigate amphiregulin (AREG) expression in the sclera during the development of form-deprivation myopia (FDM) and after the recovery of FDM in guinea pigs.
Methods: Sixty-four 2-week-old guinea pigs were randomly divided into the control and FDM groups. The right eyes of animals in FDM group were covered for 2 weeks (2 W) and 4 weeks (4 W), or were covered for 4 weeks and then uncovered for the subsequent 2 weeks (6 W).
Background: To investigate the relationships between motor fusion and sex, age and spherical equivalent (SE).
Methods: This observational study enrolled 243 healthy, nonstrabismic adults, including 94 men and 149 women aged 20 to 59 years. The subjects were divided into three groups according to SE: myopic, emmetropic and hyperopic groups.
It has been shown that flickering light can affect the development of eyeballs. However, the exact mechanism remains unclear. The ERK1/2-MMP-2 pathway is a classic pathway involved in the modulation of the extracellular matrix (ECM) in cancer tissues.
View Article and Find Full Text PDFArticle Synopsis
- - The study evaluated changes in axial length (AL) and related factors in 4- and 5-year-old children in Shanghai over a seven-year period, from 2013 to 2019, involving 2,044 participants.
- - It found no significant changes in AL for both age groups, but observed notable differences in spherical equivalent, corneal curvature, height, and weight, particularly influenced by outdoor time and being male.
- - The study concluded that while AL remained stable, further research is necessary to explore how environmental factors might impact AL growth over time.