Publications by authors named "Mahesh Prakash"

Wrist fractures and dislocations are frequently encountered in the emergency department and can cause significant long-term disability. Imaging plays a crucial role in the evaluation of wrist injuries, with conventional radiography being the first imaging investigation. Cross-sectional imaging is playing an increasingly important role in management of wrist injuries.

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This study investigates proteomic differences between knee osteoarthritis (OA) and rheumatoid arthritis (RA) to identify protein signatures with potential diagnostic and therapeutic relevance. Using SWATH mass spectrometry, synovial fluid proteome from OA patients across Kellgren-Lawrence OA grades 2, 3, and 4 was analyzed and compared with RA patients. Out of 333 quantified proteins, 45 were differentially expressed, including aggrecan, versican, and inflammation-related proteins (e.

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Objectives: To perform a Delphi-based consensus on published evidence on image-guided injections for facet joint pain (FJP) and provide clinical indications.

Methods: We report the results of an evidence-based Delphi consensus of 38 experts from the European Society of Musculoskeletal Radiology and the European Society of Neuroradiology, who reviewed the published literature for evidence on image-guided injections for FJP. Experts drafted a list of statements and graded them according to the Oxford Centre for evidence-based medicine levels of evidence.

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Diversity, equity, and inclusion (DEI) is important for delivering high-quality, culturally competent care and ensuring equal access to resources and opportunities in healthcare. However, the implementation of DEI has been met with unique challenges and successes across the globe. The International Skeletal Society (ISS), a multidisciplinary musculoskeletal society, made a conscious effort to promote DEI.

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Aim: Osteoarthritis (OA) is the eleventh most disabling condition, with radiographic classification based on the Kellgren-Lawrence (KL) grading system. Early detection is critical to implement interventions to slow disease progression and improve patient outcomes. Proteomics, as a powerful strategy, could contribute to a better understanding of the disease pathophysiology and its early detection.

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Background: Paediatric femoral fractures in children under 6 years are commonly managed with hip spica, considered the gold standard. While the remodeling potential for shortening and angular deformities is well established, the management of torsional alignment during spica application remains inadequately explored. This study proposes a novel technique to better address torsional alignment during the treatment of paediatric femoral fractures using hip spica.

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Tuberculous pyomyositis is an uncommon form of extrapulmonary tuberculosis (EPTB). We report a rare case of EPTB in a 34-year-old male post-renal transplant recipient. He presented with pain in the left hip region and fever 9 years after the renal transplantation.

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A wide variety of degenerative, inflammatory and infective arthropathies with overlapping clinical features can involve the knee joint. Due to its excellent soft tissue contrast resolution and multiplanar capability, magnetic resonance imaging (MRI) plays a significant role in early and accurate diagnosis of various arthropathies. In this article, we have provided a brief review of MRI features of various arthropathies involving the knee joint.

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Peripheral nerve imaging is a powerful tool in evaluating peripheral neuropathy. This review aims to provide an overview of the anatomy, clinical significance and pathologies of small peripheral nerves, typically less than 2 mm in diameter. High frequency ultrasound probes offer the best assessment of these nerves whilst permitting real-time clinical correlation, while the role of MRI is inherently limited by spatial resolution constraints and the lack of patient contact.

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Objective: To assess the reliability and reproducibility of AO/OTA, Frykman and Fernandez classification systems for distal radius fractures on CT.

Materials And Methods: Four radiologists, including one radiology resident, two musculoskeletal radiology fellows and one radiology consultant independently evaluated CT scans of 115 patients with distal radius fractures and classified the fractures according to AO/OTA, Frykman and Fernandez classification system. To assess reproducibility, a second set of reading was done by two observers after an interval of six weeks.

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Background: The straight and thin design of the CLS Spotorno stem makes it prone for coronal plane mal-alignment, with potential for cortical impingement; reactive osteogenesis and thigh pain have been documented in this situation with some stems. The literature is scarce about the effect of distal mal-alignment with this particular stem, and its relationship with thigh pain, functional outcomes and stem survival. We assessed functional outcomes with incidence of varus/valgus CLS stem alignment, and correlated stem subsidence of these thin stems with hip scores.

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Article Synopsis
  • * Out of 54 leprosy patients initially assessed, a significant portion showed symptoms like loss of sensation (68.5%) and paresthesia (37.0%), with notable improvements in nerve function observed, particularly in the ulnar and radial nerves after treatment (P < 0.05).
  • * The study found that some abnormal HRUS-CD results were linked to factors like more serious leprosy cases, age, and flare-ups of the disease, concluding that
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Understanding the three-dimensional anatomy of the talar neck is essential in assessing the accuracy of reduction in talar neck fractures as well as for planning surgical correction for talar malunions. However, the geometrical parameters that describe this anatomy are sparsely reported in the orthopedics literature. We aimed to identify from the existing literature, geometrical parameters that describe the anatomy of the talar neck, determine how these are measured, and their normative values.

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When a low-energy trauma induces an acute vertebral fracture (VF) with clinical symptoms, a definitive diagnosis of osteoporotic vertebral fracture (OVF) can be made. Beyond that, a "gold" radiographic standard to distinguish osteoporotic from non-osteoporotic VFs does not exist. Fracture-shaped vertebral deformity (FSVD) is defined as a deformity radiographically indistinguishable from vertebral fracture according to the best of the reading radiologist's knowledge.

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Arthropathies are a frequent cause of shoulder pain and comprise of a wide range of clinical entities that may pose a diagnostic challenge. Though history and clinical examination remain vital, imaging plays a pivotal role in accurate diagnosis. Magnetic resonance imaging (MRI) remains an invaluable tool for imaging evaluation of shoulder involvement by various arthropathies.

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Purpose: The choice of entry point, Greater trochanter (GT), or Piriformis entry (PE) for antegrade intramedullary nailing (IMN) of the femur is crucial. This study was performed to compare these two entry points in the patients with shaft of femur fractures regarding intra-operative parameters, radiological and functional outcomes.

Materials And Methods: Twenty-four patients underwent GT entry nailing, while 25 patients underwent PE nailing.

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 Osteoarthritis (OA) is the commonest form of arthritis with pain and disability as hallmark symptoms. Despite various nonpharmacologic, pharmacologic, and surgical approaches, pain control may be hard to achieve. Over the last few years, few studies have been conducted on managing knee OA using novel endovascular genicular artery embolization (GAE) with varied outcomes.

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Purpose: The purpose of this study was to evaluate the characteristics of distal radius fractures (DRFs) in patients undergoing multi-detector computed tomography (MDCT) and their association with carpal and distal ulnar fractures.

Methods: This retrospective study analyzed 120 patients, who underwent MDCT for evaluation of DRFs. Two radiologists independently evaluated the data for various fracture characteristics and for associated carpal and distal ulnar fractures.

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Objectives: Prevalence of synovitis, tenosynovitis, erosions, acro-osteolysis and bone marrow edema in systemic sclerosis is not extensively reported. We aimed to estimate the prevalence of changes in individual joints of hands in systemic sclerosis patients.

Method: A cross-sectional analytical study consisting of 34 adults (females,  = 32) with systemic sclerosis.

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Article Synopsis
  • Metabolic bone diseases, particularly osteoporosis, significantly affect health care systems and patient well-being, mainly through vertebral fractures (VFs).
  • This review highlights advanced imaging techniques for diagnosing and quantifying VFs, with a specific focus on different populations, including children.
  • It concludes by discussing the future of osteoporosis screening, emphasizing opportunistic diagnosis and the role of artificial intelligence in improving detection methods.
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Metabolic bone diseases comprise a wide spectrum. Of them, osteoporosis is the most frequent and the most commonly found in the spine, with a high impact on health care systems and on morbidity due to vertebral fractures (VFs).This article discusses state-of-the-art techniques on the imaging of metabolic bone diseases in the spine, from the well-established methods to the latest improvements, recent developments, and future perspectives.

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Article Synopsis
  • The study compares shear-wave elastography (SWE), gray scale (GS) ultrasound, and power Doppler (pD) for diagnosing Achilles tendinopathy in psoriatic patients, examining the correlation with achillodynia and disease severity using the psoriasis area and severity index (PASI).
  • In a sample of 100 Achilles tendons, SWE identified abnormal tendons in 71% of cases, while conventional methods only detected abnormalities in 23.21% of psoriatic arthritis cases and none in controls.
  • The research found significant negative correlations between SWE values and the duration of arthritis, as well as achillodynia and PASI scores, suggesting that SWE is a reliable, non
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