The Role of Bystander Cardiopulmonary Resuscitation: A Meta-Analysis.

This meta-analysis systematically evaluated the impact of bystander cardiopulmonary resuscitation (BCPR) on the survival of patients with out-of-hospital cardiac arrest (OHCA) and related factors. A computerized search of China National Knowledge Infrastructure (CNKI), Wanfang Database, Chinese Biomedical Literature Database (CBM), PubMed, and Embase was conducted from the database's inception to May 1, 2023. The study included observational studies of patients who experienced OHCA and were successfully resuscitated using BCPR, following the predetermined criteria for inclusion and exclusion.

CircABCA1 promotes ccRCC by reprogramming cholesterol metabolism and facilitating M2 macrophage polarization through IGF2BP3-mediated stabilization of SCARB1 mRNA.

Background: The reliance of clear cell renal cell carcinoma (ccRCC) on exogenous cholesterol import implies a metabolic susceptibility. This susceptibility represents a potential avenue that can be exploited as a novel therapeutic approach for ccRCC. Circular RNAs (circRNAs) are emerging regulators in cancer, yet their roles in ccRCC lipid metabolism and tumor microenvironment remodeling remain unclear.

Surface Characterization of N-Heterocyclic Carbenes on Gold and Silver: Exploring Distinct Crystalline Facets.

Due to its exceptional chemical and functional versatility, N-heterocyclic carbene chemistry holds great promise in replacing thiol chemistry for applications in next-generation nanoelectronics. To manipulate their chemical properties and interfacial characteristics, a wide range of substrates needs to be employed for the formation of self-assemblies. Research has, however, predominantly focused on the Au(111) substrate.

Association of urine parabens with liver function in US adolescents based on NHANES 2007-2016.

Paraben esters are commonly used as preservatives in cosmetics, personal hygiene products, food and drugs. However, there is a lack of evidence regarding the impact of exposure to Paraben esters on adolescent liver function. We analyzed data from the 2007-2016 National Health and Nutrition Examination Survey (NHANES).

The Impact of Gamified Interventions on the Management of Chronic Obstructive Pulmonary Disease: Systematic Literature Review.

Background: Chronic obstructive pulmonary disease (COPD) requires consistent sustained management, including regular physical activity, pulmonary rehabilitation, and self-care adherence. Despite strong clinical guidelines, patient engagement remains a major challenge, leading to suboptimal disease control and increased health care use. Gamified interventions have emerged as potential tools to improve adherence, motivation, and outcomes in chronic disease management.

Development of Sustainable, Low-Shrinkage Concrete Through Optimized Aggregate Gradation, Cement Reduction, and Internal Curing.

The durability of concrete is compromised by early-age cracking, which provides a pathway for harmful ions and water to penetrate the material. Early-age cracking, however, is most commonly caused by concrete shrinkage. This study investigates strategies for minimizing the shrinkage of concrete by optimizing aggregate gradation via the Tarantula Curve, reducing cement content, and incorporating lightweight fine aggregates (LWFA) as internal curing agents.

[Analysis of clinical phenotype and gene variation of a child with neurodevelopmental disorder caused by homozygous variation of TRAPPC6B gene].

Objective: To explore the clinical phenotype and genetic characteristics of a child with neurodevelopmental disorder caused by homozygous frameshift variant of the TRAPPC6B gene, and to provide reference for the diagnosis of the disease.

Methods: A child with neurodevelopmental disorder caused by homozygous variant of TRAPPC6B gene who was admitted to the Children's Hospital Affiliated to Zhengzhou University in March 2023 due to "inability to stand and walk independently at 1 year and 3 months old" was selected as the study object. The clinical data were collected by retrospective analysis method.

Optical Spectroscopic Probing and Atomic Visualization of the Motion of N-Heterocyclic Carbenes on Ag(111).

The application of N-heterocyclic carbenes (NHCs) as versatile anchors for planar surface modifications has been well documented over the past decade. Despite its fundamental importance to the formation of self-assembled NHC monolayers on surfaces, the microscopic mechanism behind the mobility of NHCs has primarily been explored through theoretical studies; an atomic-level experimental understanding of NHC motion on surfaces remains elusive. Here, we combine tip-enhanced Raman spectroscopy (TERS) and scanning tunneling microscopy (STM) to investigate the mobility of a model NHC on Ag(111).

Efficacy of Group O Washed Red Blood Cell Transfusion on Vital Signs and Hematologic Stability in Trauma Patients With Different Blood Types.

Objective: To comprehensively assess the impact of emergency transfusion of group O washed red blood cells on the vital signs and hematological parameters of patients with severe trauma and to analyze the differential responses among different blood types, thereby providing valuable evidence for optimizing transfusion strategies.

Methods: A retrospective analysis was conducted on the clinical data of patients with severe trauma who underwent emergency transfusion in the hospital's emergency department from April 2023 to March 2024. Changes in blood biochemical indexes and vital signs before and after transfusion were compared, and adverse transfusion reactions were monitored.

Atomistic Insights into Elemental Two-Dimensional Materials and Their Heterostructures.

Inspired by the success of graphene, two-dimensional (2D) materials have been at the forefront of advanced (opto-)nanoelectronics and energy-related fields owing to their exotic properties like sizable bandgaps, Dirac fermions, quantum spin Hall states, topological edge states, and ballistic charge carrier transport, which hold promise for various electronic device applications. Emerging main group elemental 2D materials, beyond graphene, are of particular interest due to their unique structural characteristics, ease of synthetic exploration, and superior property tunability. In this review, we present recent advances in atomic-scale studies of elemental 2D materials with an emphasis on synthetic strategies and structural properties.

[Clinical and genetic analysis of a child with Lamb-Shaffer syndrome due to a de novo variant of SOX5 gene].

Objective: To explore the clinical features of a child with Lamb-Shaffer syndrome (LAMSHF) due to a variant of SOX5 gene.

Methods: A child who was admitted to Children's Hospital Affiliated to Zhengzhou University in July 2022 was selected as the study subject. Clinical data of the child was collected.

[Genetic analysis of a child with Dias-Logan syndrome due to variant of BCL11A gene].

Objective: To analyze the clinical and genetic characteristics of a child featuring Dias-Logan syndrome.

Methods: A child with speech disorders and delayed psychomotor development from childhood who was admitted to the Rehabilitation Medicine Department of Children's Hospital Affiliated to Zhengzhou University in July 2022 was selected as the research subject. Clinical data of the child was collected.

Borophene: Synthesis, Chemistry, and Electronic Properties.

As a neighbor of carbon in the periodic table, boron exhibits versatile structural and electronic configurations, with its allotropes predicted to possess intriguing structures and properties. Since the experimental realization of two-dimensional (2D) boron sheets (borophene) on Ag(111) substrates in 2015, the experimental study of the realization and characteristics of borophene has drawn increasing interest. In this review, we summarize the synthesis and properties of borophene, which are mainly based on experimental results.

Numerical study of Richtmyer-Meshkov instability in finite thickness fluid layers with reshock.

The evolution of a shock-induced fluid layer is numerically investigated in order to reveal the underlying mechanism of the Richtmyer-Meshkov instability under the effect of a reshock wave. Six different types of fluid layer are initially set up to study the effect of amplitude perturbation, fluid-layer thickness, and phase position on the reshocked fluid-layer evolution. Interface morphology results show that the interface-coupling effect gets strengthened when the fluid-layer thickness is small, which means the development of spikes and bubbles is inhibited to some extent compared to the case with large initial fluid-layer thickness.

Nanoscale Chemical Probing of Metal-Supported Ultrathin Ferrous Oxide via Tip-Enhanced Raman Spectroscopy and Scanning Tunneling Microscopy.

Metal-supported ultrathin ferrous oxide (FeO) has attracted immense interest in academia and industry due to its widespread applications in heterogeneous catalysis. However, chemical insight into the local structural characteristics of FeO, despite its critical importance in elucidating structure-property relationships, remains elusive. In this work, we report the nanoscale chemical probing of gold (Au)-supported ultrathin FeO via ultrahigh-vacuum tip-enhanced Raman spectroscopy (UHV-TERS) and scanning tunneling microscopy (STM).

[Factors Influencing Willingness of Farmers to Pay for Agricultural Non-point Source Pollution Control Based on Distributed Cognitive Theory].

The analysis of the willingness of individual farmers to cover costs is an important basis for measuring the economic value of agricultural non-point pollution management， and determining the ecological and economic value of rural surface pollution control is a necessary measure to internalize the externalities of agricultural production. Based on the analysis of the hierarchy of factors influencing the cognition of farmers， this study constructed a theoretical framework based on distributed cognition theory to analyze their willingness to pay for agricultural non-point source pollution control from the perspective of individual farmers. On the basis of this framework， we used the Double-Hurdle model to empirically test the overall process of farmers'willingness to pay and their willingness to pay the amount for agricultural non-point source pollution control by combining 531 microscopic research datapoints in Guanzhong， Shaanxi Province.

[Clinical characteristics and genetic analysis of two children with Tuberous sclerosis complex].

Objective: To explore the clinical characteristics and genetic variants in two children with Tuberous sclerosis complex (TSC).

Methods: Two children who had presented at the Children's Hospital Affiliated to Zhengzhou University respectively in June 2020 and July 2021 were selected as the study subjects. Clinical data of the children were collected, and potential pathogenic variants were screened by whole exome sequencing (WES).

Can low-carbon cities increase urban housing prices? Evidence from China's low-carbon city pilot.

The low-carbon transformation is a broad and profound systemic change that will inevitably impact many areas of the urban environment, economy, and social system. We evaluated the impact of China's ongoing "low-carbon pilot policy" on urban housing prices as a "quasi-natural experiment." Existing research findings and hedonic theory predictions suggest that the low-carbon city pilot (LCCP) policy is increasing urban housing prices through air quality improvements.

[Analysis of CLCN4 gene variant in a child with Raynaud-Claes syndrome].

Objective: To analyze the clinical phenotype and genetic variant in a child with Raynaud-Claes syndrome (RCS).

Methods: A child who was diagnosed with RCS at the Children's Hospital Affiliated to Zhengzhou University for delayed language and motor development in August 2022 was selected as the study subject. Clinical data of the child were collected, and potential genetic variant was detected by next-generation sequencing and Sanger sequencing.

[Application of fluorescence in situ hybridization combined with chromosomal karyotyping analysis in children with disorders of sex development due to sex chromosome abnormalities].

Objective: To retrospectively analyze sex chromosomal abnormalities and clinical manifestations of children with disorders of sex development (DSD).

Methods: A total of 14 857 children with clinical features of DSD including short stature, cryptorchidism, hypospadia, buried penis and developmental delay were recruited from Zhengzhou Children's Hospital from January 2013 to March 2022. Fluorescence in situ hybridization (FISH) and chromosomal karyotyping were carried out for such children.

Sodium butyrate reduces ammonia production in the cecum of laying hens by regulating ammonia-producing bacteria.

Sodium butyrate is a commonly used feed additive and can reduce ammonia (NH) emissions from laying hens, but the mechanism of this effect is unknown. In this study, the sodium butyrate and cecal content of Lohmann pink laying hens were measured, and in vitro fermentation experiments and NH-producing bacteria coculture experiments were carried out to explore the relationship between NH emissions and its associated microbiota metabolism. Sodium butyrate was found to significantly reduce NH emission from the cecal microbial fermentation of Lohmann pink laying hens (P < 0.

The fate of antibiotic resistance genes and their association with bacterial and archaeal communities during advanced treatment of pig farm wastewater.

Advanced wastewater treatment plants are widely used in most large-scale pig farms in southern China. However, the fate of antibiotic resistance genes (ARGs) and their association with bacterial and archaeal communities during advanced wastewater treatment remain unclear. In this study, the profiles of ARGs in typical advanced wastewater treatment plants were surveyed using metagenomic analysis.

Organic Fertilizer Application Mediates Tomato Defense Against pv. , Possibly by Reshaping the Soil Microbiome.

Bacterial speck caused by pv. is a serious foliar disease on tomato. However, it is still unknown how organic fertilizers application mediates plant defense against foliar pathogens by altering the composition of the soil microbial community.