Short-wave infrared (SWIR) polarization imaging using division-of-focal-plane imaging polarimeter.

This study investigates the polarization properties of materials in the short-wave infrared (SWIR) spectrum using a compact division-of-focal-plane imaging polarimeter. The polarimeter is constructed by packaging a micro-polarizer array on top of an InGaAs sensor. Experiments conducted in both indoor and outdoor environments revealed unique transparency, absorption, and polarization behaviors across various materials.

Corrigendum: Microfluidic-based human prostate-cancer-on-chip.

[This corrects the article DOI: 10.3389/fbioe.2024.

Carboxymethyl Chitosan as a Reversible Template of Calcium Phosphate for Multifunctional Conservation of Carbonate Stone.

The accelerated deterioration of carbonate stone artifacts under climate change has long been an urgent issue. Inspired by biomineralization, we developed carboxymethyl chitosan-diammonium hydrogen phosphate (CD) composite and investigated the conservation effectiveness of the CD composite compared to diammonium hydrogen phosphate (DAP) on limestone. The morphologies and microstructures were characterized using scanning electron microscopy (SEM), X-ray diffraction (XRD), and Fourier-transform infrared spectroscopy (FT-IR).

Microfluidic Applications in Prostate Cancer Research.

Prostate cancer is a disease in which cells in the prostate, a gland in the male reproductive system below the bladder, grow out of control and, among men, it is the second-most frequently diagnosed cancer (other than skin cancer). In recent years, prostate cancer death rate has stabilized and, currently, it is the second-most frequent cause of cancer death in men (after lung cancer). Most deaths occur due to metastasis, as cancer cells from the original tumor establish secondary tumors in distant organs.

Microfluidic-based human prostate-cancer-on-chip.

Lack of adequate models significantly hinders advances in prostate cancer treatment, where resistance to androgen-deprivation therapies and bone metastasis remain as major challenges. Current models fail to faithfully mimic the complex prostate physiology. animal models can shed light on the oncogenes involved in prostate cancer development and progression; however, the animal prostate gland is fundamentally different from that of human, and the underlying genetic mechanisms are different.

Polarization properties and Umov effect of human hair.

This study delves into the polarization properties of various hair colors using several techniques, including polarization ray tracing, full Stokes, and Mueller matrix imaging. Our analysis involved studying hair in both indoor and outdoor settings under varying lighting conditions. Our results demonstrate a strong correlation between hair color and the degree of linear polarization.

Drosophila CASK regulates brain size and neuronal morphogenesis, providing a genetic model of postnatal microcephaly suitable for drug discovery.

Background: CASK-related neurodevelopmental disorders are untreatable. Affected children show variable severity, with microcephaly, intellectual disability (ID), and short stature as common features. X-linked human CASK shows dosage sensitivity with haploinsufficiency in females.

Birefringent coating to remove polarization aberrations.

Polarization aberrations are found in most optical components due to a materials-differing response to s- and p-polarizations. This differing response can manifest either as diattenuation, retardance, or both. Correction of polarization aberrations, such as these, are critical in many applications such as interferometry, polarimetry, display, and high contrast imaging, including astronomy.

Generalized elliptical retarder design and construction using nematic and cholesteric phase liquid crystal polymers.

Elliptical retarders have important applications in interferometry and polarimetry, as well as imaging and display technologies. In this work, we discuss the traditional elliptical retarder decomposition using Pauli matrices as basis sets and then introduce a solution to the inverse problem: how an arbitrary elliptical retarder with desired eigenpolarizations and retardance can be constructed using a combination of linear and circular retarders. We present a simple design process, based on eigen-decomposition, with a solution determined by the intrinsic properties of each individual retarder layer.

Extracellular Fluid Flow Induces Shallow Quiescence Through Physical and Biochemical Cues.

The balance between cell quiescence and proliferation is fundamental to tissue physiology and homeostasis. Recent studies have shown that quiescence is not a passive and homogeneous state but actively maintained and heterogeneous. These cellular characteristics associated with quiescence were observed primarily in cultured cells under a static medium.

Patterned achromatic elliptical polarizer for short-wave infrared imaging polarimetry.

Short-wave infrared (SWIR) imaging polarimetry has widespread applications in telecommunication, medical imaging, surveillance, remote-sensing, and industrial metrology. In this work, we design, fabricate, and test an achromatic SWIR elliptical polarizer, which is a key component of SWIR imaging polarimetry. The elliptical polarizer is made of a patterned linear polarizer and a patterned optical elliptical retarder.

Application of Microfluidic Systems for Breast Cancer Research.

Cancer is a disease in which cells in the body grow out of control; breast cancer is the most common cancer in women in the United States. Due to early screening and advancements in therapeutic interventions, deaths from breast cancer have declined over time, although breast cancer remains the second leading cause of cancer death among women. Most deaths are due to metastasis, as cancer cells from the primary tumor in the breast form secondary tumors in remote sites in distant organs.

Patterned liquid crystal polymer C-plate retarder and color polarizer.

The patternability and guest-host interaction with dichroic dye and C-plate liquid crystal polymer (LCP) materials are investigated, and the optical properties of a thin film C-plate retarder and polarizer are studied and compared with theory. The C-plate retarder is a waveplate made of a uniaxial LCP where the optical axis of the LCP is parallel to the surface normal of the optic. No retardance is observed at a normal angle of incidence and retardance grows as the angle of incidence increases.

Microfabrication of a color filter array utilizing colored SU-8 photoresists.

Patterned color filter arrays are important components in digital cameras, camcorders, scanners, and multispectral detection and imaging instruments. In addition to the rapid and continuous progress to improve camera resolution and the efficiency of imaging sensors, research into the design of color filter arrays is important to extend the imaging capability beyond conventional applications. This paper reports the use of colored SU-8 photoresists as a material to fabricate color filter arrays.

Division of focal plane red-green-blue full-Stokes imaging polarimeter.

We calibrate and test a division-of-focal-plane red-green-blue (RGB) full-Stokes imaging polarimeter in a variety of indoor and outdoor environments. The polarimeter, acting as a polarization camera, utilizes a low dispersion microretarder array on top of a sensor with Bayer filters and wire-grid linear polarizers. We also present the design and fabrication of the microretarder array and the assembly of the camera and validate the performance of the camera by taking multiple RGB full-Stokes images and videos.

Pharmacokinetic Analysis of Epithelial/Endothelial Cell Barriers in Microfluidic Bilayer Devices with an Air-Liquid Interface.

As the range of applications of organs-on-chips is broadening, the evaluation of aerosol-based therapies using a lung-on-a-chip model has become an attractive approach. Inhalation therapies are not only minimally invasive but also provide optimal pharmacokinetic conditions for drug absorption. As drug development evolves, it is likely that better screening through use of organs-on-chips can significantly save time and cost.

Observation of elliptically polarized light from total internal reflection in bubbles.

Bubbles are ubiquitous in the natural environment, where different substances and phases of the same substance forms globules due to differences in pressure and surface tension. Total internal reflection occurs at the interface of a bubble, where light travels from the higher refractive index material outside a bubble to the lower index material inside a bubble at appropriate angles of incidence, which can lead to a phase shift in the reflected light. Linearly polarized skylight can be converted to elliptically polarized light with efficiency up to 53% by single scattering from the water-air interface.

Permeability of Epithelial/Endothelial Barriers in Transwells and Microfluidic Bilayer Devices.

Lung-on-a-chip (LoC) models hold the potential to rapidly change the landscape for pulmonary drug screening and therapy, giving patients more advanced and less invasive treatment options. Understanding the drug absorption in these microphysiological systems, modeling the lung-blood barrier is essential for increasing the role of the organ-on-a-chip technology in drug development. In this work, epithelial/endothelial barrier tissue interfaces were established in microfluidic bilayer devices and transwells, with porous membranes, for permeability characterization.

Polarizing beam splitter cube for circularly and elliptically polarized light.

A method of designing an arbitrary polarizing beam splitter (PBS) cube using multiple layers of thin-film liquid crystal polymer is demonstrated. This methodology utilizes cholesteric phase liquid crystal polymer (Ch-LCP) to transmit one handedness of elliptically polarized light and reflect the orthogonal state when unpolarized light is incident. Using additional nematic liquid crystal polymer layers, the polarization state for the transmitted and reflected light can be controlled and output to any two orthogonal states represented on the Poincaré sphere.

De novo transcriptome analysis and differentially expressed genes in the ovary and testis of the Japanese mantis shrimp Oratosquilla oratoria by RNA-Seq.

The mantis shrimp Oratosquilla oratoria is a widely distributed, commercially important crustacean species. Although its conservation and the development of successful artificial breeding technologies have recently received considerable attention, there are currently no available data regarding the molecular mechanisms in controlling reproduction. In this study, we performed transcriptome sequencing of the testis, ovary, female and male eyestalks and the androgenic gland of O.

Design, fabrication and testing of achromatic elliptical polarizer.

A method of designing achromatic elliptical polarizers using a combination of multiple birefringent waveplates is demonstrated. This approach has a simple geometric interpretation and simplifies the problem of designing an achromatic elliptical polarizer to find overlapping arcs on the Poincaré sphere. The technique is applied to the design of achromatic elliptical polarizers for a broadband division-of-focal-plane full-Stokes imaging polarimeter for visible wavelength band (λ = 450nm to 650nm).

Specific interactions between functionalised particles and circulating tumour cells.

Receptor-ligand binding has been one of the more popular approaches to specifically targeting tumour cells. In this work, targeting efficiency was quantitatively characterized using silica particles functionalized with EpCAM antibodies and EpCAM-expressing BT-20 breast cancer cells. The effects of incubation time and particle concentration on the number of functionalised particles bound to target cells were experimentally investigated.