Enhanced hyper tuning using bioinspired-based deep learning model for accurate lung cancer detection and classification.

Lung cancer (LC) is one of the leading causes of cancer related deaths worldwide and early recognition is critical for enhancing patient outcomes. However, existing LC detection techniques face challenges such as high computational demands, complex data integration, scalability limitations, and difficulties in achieving rigorous clinical validation. This research proposes an Enhanced Hyper Tuning Deep Learning (EHTDL) model utilizing bioinspired algorithms to overcome these limitations and improve accuracy and efficiency of LC detection and classification.

Recent potential application of metal organic framework as a sensor for the detection of dioxin and dioxin-like organic pollutants.

Most organic pollutants pose significant risks to public health and the environment. Of particular concern, toxic chemicals in the environment may lead to a variety of health disorders, including cancer and asthma. There are various classes of organic pollutants, including pesticides, dioxins, volatile organic compounds (VOCs), polychlorinated biphenyls, aromatic hydrocarbons, and polyaromatic hydrocarbons.

Tailored NADES solvents for the extraction optimization of benzylisoquinoline alkaloids from Thalictrum foliolosum DC.- A potential phyto-nutraceutical source.

From a perspective focused on phyto-nutraceuticals, alkaloids are considered to be the most significant metabolites, as they exhibit a broad range of pharmacological applications. Therefore, it is essential, to conduct a thorough investigation of the extraction techniques employed and to optimize the overall process. Considering this, we delved into tailor-made natural deep eutectic solvents coupled with ultrasonic-assisted extraction and macroporous resins aided recovery of therapeutics alkaloids from Thalictrum foliolosum DC.

NADES-based extraction optimization and enrichment of Cyanidin-3-O-galactoside from Rhododendron arboreum Sm.: Kinetics and thermodynamics insights.

Cyanidin-3-O-galactoside (Cy3-gal) is the most widespread anthocyanin that has been found to be applicable to nutraceutical and pharmaceutical ingredients. Nevertheless, the process of separation and purification, susceptibilities to heat, and pH inactivation present some limitations. In the present study, natural deep eutectic solvents (NADES) with an ultrasonic-assisted extraction method were briefly studied, and the recovery of Cy3-gal from Rhododendron arboreum was highlighted.

Longitudinal assessment of extreme climate events in Kinnaur district, Himachal Pradesh, north-western Himalaya, India.

It is vital to keep an eye on changes in climatic extremes because they set the stage for current and potential future climate, which usually have a reasonable adverse impact on ecosystems and society. The present study examines the variability and trends in precipitation and temperature across seasons in the Kinnaur district, offering valuable insights into the complex dynamics of the Himalayan climate. Using Climatic Research Unit gridded Time Series (CRU TS) datasets from 1951 to 2021, the study analyzes the data to produce 28 climate indices based on India Meteorological Department (IMD) convention indices and Expert Team on Climate Change Detection and Indices (ETCCDI).

Food and Antioxidant Supplements with Therapeutic Properties of Morchella esculenta (Ascomycetes): A Review.

Morchella esculenta, commonly known as yellow morels, is an edible and medicinal mushroom popular worldwide for its unique flavor and culinary purposes. The traditional medical system effectively uses morels against infertility, fatigue, cancer, muscular pain, cough, and cold. The M.

A Novel Rhodamine Probe Acting as Chemosensor for Selective Recognition of Cu and Hg Ions: An Experimental and First Principle Studies.

Copper and Mercury ions have vital role to play in biological world as their excess or deficiency can cause different type of diseases in human being as well as biological species including plants and animals. Therefore, their detection at trace level becomes very important in term of biological. The current studies embody the fabrication, structural characterization and recognition behavior of a novel rhodamine B hydrazone formed when hydrazide of rhodamine B was condensed with 5-Allyl-3-methoxy salicylaldehyde (RBMA).

A dual channel rhodamine appended smart probe for selective recognition of Cu and Hg via "turn on" optical readout.

A new rhodamine-6G hydrazone RHMA has been synthesized using rhodamine-6G hydrazide and 5-Allyl-3-methoxysalicylaldehyde. RHMA has been fully characterized with different spectroscopic methods and single crystal XRD. RHMA can selectively recognize Cu and Hg in aqueous media amongst other common competitive metal ions.

In vitro Propagation of Endemic Species Mahonia Jaunsarensis Ahrendt Through Callus Culture.

Mahonia jaunsarensis Ahrendt (Family Berberidaceae) an endemic species was successfully propagated in vitro. An efficient propagation protocol has been developed first time. The callus cultures were established from leaf explants on Murashige and Skoog (MS) medium supplemented with 2,4-Dichlorophenoxyacetic acid (2,4-D; 1 µM) and resulted 70% callus induction with green compact callus.

Predicting the potential distribution of Dactylorhiza hatagirea (D. Don) Soo-an important medicinal orchid in the West Himalaya, under multiple climate change scenarios.

Climate variability coupled with anthropogenic pressures is the most critical driver in the Himalayan region for forest ecosystem vulnerability. Dactylorhiza hatagirea (D.Don) Soo is an important yet highly threatened medicinal orchid from the Himalayan region.

Saturated and Polyunsaturated Fatty Acids Rich Populations of Prinsepia utilis Royle in Western Himalaya.

The study aims to identify the fatty acid composition in Prinsepia utilis seeds collected from diverse populations of Western Himalaya, India. The seeds contained higher saturated fatty acid (SFA-43.09%; Average of all populations) followed by polyunsaturated fatty acid (PUFA - 29.

The Pharmacological Activities of L.: A Review Based on the Mechanisms and Therapeutic Opportunities of its Phytoconstituents.

species are mainly distributed in North Africa, Southern and Central Europe, and Western Asia, used in gardens and parks as ornamental plants, while L. (saffron) is the only species that is cultivated for edible purpose. The use of saffron is very ancient; besides the use as a spice, saffron has long been known also for its medical and coloring qualities.

Curcumin as a Natural Remedy for Atherosclerosis: A Pharmacological Review.

Curcumin, a natural polyphenolic compound present in L. rhizomes, shows potent antioxidant, anti-inflammatory, anti-cancer, and anti-atherosclerotic properties. Atherosclerosis is a comprehensive term for a series of degenerative and hyperplasic lesions such as thickening or sclerosis in large- and medium-sized arteries, causing decreased vascular-wall elasticity and lumen diameter.

Phytotherapy and food applications from Brassica genus.

Plants of the genus Brassica occupy the top place among vegetables in the world. This genus, which contains a group of six related species of a global economic significance, three of which are diploid: Brassica nigra (L.) K.

Ethnopharmacological Applications Targeting Alcohol Abuse: Overview and Outlook.

Excessive alcohol consumption is the cause of several diseases and thus is of a major concern for society. Worldwide alcohol consumption has increased by many folds over the past decades. This urgently calls for intervention and relapse counteract measures.

Avocado-Soybean Unsaponifiables: A Panoply of Potentialities to Be Exploited.

Avocado and soybean unsaponifiables (ASU) constitute vegetable extracts made from fruits and seeds of avocado and soybean oil. Characterized by its potent anti-inflammatory effects, this ASU mixture is recommended to act as an adjuvant treatment for osteoarthritic pain and slow-acting symptomatic treatment of hip and knee osteoarthritis; autoimmune diseases; diffuse scleroderma and scleroderma-like states (e.g.

Early Neurodevelopmental Outcome of Very Low Birthweight Neonates with Culture-positive Blood Stream Infection: A Prospective Cohort Study.

Aim Our study aimed to evaluate the early neurodevelopmental outcomes of very low birthweight (VLBW) neonates with culture-proven sepsis compared with VLBW neonates without sepsis. Materials and methods Our study included 80 VLBW neonates with blood culture-proven sepsis and 80 VLBW neonates without sepsis. For each neonate with sepsis, a control neonate of matching gender and gestational age was selected.

Yttrium Copper Titanate as a Highly Efficient Electrocatalyst for Oxygen Reduction Reaction in Fuel Cells, Synthesized via Ultrafast Automatic Flame Technique.

Replacing platinum (Pt) metal-based electrocatalysts used in the oxygen reduction reaction (ORR) in fuel cells is an important research topic due to the high cost and scarcity of Pt, which have restricted the commercialization of these clean-energy technologies. The ABO-type perovskite family of an ACuTiO (A = Ca, Y, Bi, and La) polycrystalline material can serve as an alternative electrocatalyst for the ORR in terms of low-cost, activity, and stability. These perovskite materials may be considered the next generation electro-catalyst for the ORR because of their photocatalytic activity and physical and chemical properties capable of containing a wide range of A- and B-site metals.